Blood Vessels News and Research

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PDE4 enzyme regulates division of tumour cells and blood vessel growth in cancer tissue

Lung cancer is the leading cause of cancer death throughout the world. Standard treatment methods do not usually result in long-term recovery. In addition to the proliferation of the tumour cells, the growth of blood vessels controls tumors development. The blood vessel growth is controlled by several signalling molecules. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim and Justus Liebig University Giessen have discovered a molecule that plays a key role in this process. They succeeded in reducing tumour growth in their experiments by blocking the phosphodiesterase PDE4.

5 May 2012

LRI applauds ACR colleagues for new lupus nephritis guidelines

The Lupus Research Institute (LRI) applauds our colleagues at the American College of Rheumatology (ACR) for issuing new guidelines to help healthcare professionals screen, diagnose and treat lupus nephritis, a type of kidney disease associated with lupus. Available on the ACR website, the new guidelines are just published in the April 2012 issue of Arthritis Care & Research.

5 May 2012

Andrew Technologies launches HydraSolve Lipoplasty System at ASAPS meeting

Andrew Technologies, LLC launched the HydraSolve Lipoplasty System today at the American Society of Aesthetic Plastic Surgery (ASAPS) in Vancouver, BC.

5 May 2012

Hypoxia may be a primary cause of uncontrollable tumor growth in cancers

Low oxygen levels in cells may be a primary cause of uncontrollable tumor growth in some cancers, according to a new University of Georgia study. The authors' findings run counter to widely accepted beliefs that genetic mutations are responsible for cancer growth.

4 May 2012

Scientists identify first gene associated with congenital asplenia

Researchers at Weill Cornell Medical College and Rockefeller University have identified the first gene to be linked to a rare condition in which babies are born without a spleen, putting those children at risk of dying from infections they cannot defend themselves against. The gene, Nkx2.5, was shown to regulate genesis of the spleen during early development in mice.

4 May 2012

Large-scale, patient-specific simulations of blood function

Having a virtual copy of a patient's blood in a computer would be a boon to researchers and doctors. They could examine a simulated heart attack caused by blood clotting in a diseased coronary artery and see if a drug like aspirin would be effective in reducing the size of such a clot.

3 May 2012

Study investigates use of stem cells to treat lower-limb peripheral artery disease

Research led by vascular surgeons at Dartmouth-Hitchcock may offer new hope to sufferers of peripheral artery disease, the cause of nearly 60,000 lower-limb amputations annually, through the use of a patient's own stem cells.

3 May 2012

Study confirms that COX-2 inhibitors predispose people to cardiovascular disease

After nearly 13 years of study and intense debate, a pair of new papers from the Perelman School of Medicine, at the University of Pennsylvania have confirmed exactly how a once-popular class of anti-inflammatory drugs leads to cardiovascular risk for people taking it.

3 May 2012

Novel technique helps surgeons to remove 'inoperable' abdominal tumors

Abdominal tumors involving both roots of the celiac and superior mesenteric artery (SMA) are deemed unresectable by conventional surgical methods, as removal would cause necrosis of the organs that are supplied by those blood vessels.

2 May 2012

Cameron Health's subcutaneous ICD for sudden cardiac arrest receives FDA advisory panel approval

Cameron Health, Inc., a pioneer in the development, manufacture and distribution of next generation implantable cardioverter defibrillators (ICDs), announced today that the U.S. Food and Drug Administration (FDA) Circulatory System Devices Panel voted 7-1 that sufficient data exists demonstrating the efficacy and safety of the S-ICD System for the treatment of sudden cardiac arrest (SCA).

27 Apr 2012

GSK receives FDA approval for Votrient to treat advanced soft tissue sarcoma

The U.S. Food and Drug Administration today approved Votrient (pazopanib) to treat patients with advanced soft tissue sarcoma who have previously received chemotherapy. Soft tissue sarcoma is a cancer that begins in the muscle, fat, fibrous tissue, and other tissues.

27 Apr 2012

UMKC School of Medicine receives $400,000 gift to establish Pulmonary Fibrosis Research Program

The University of Missouri-Kansas City has received a $400,000 gift to establish a pulmonary fibrosis research program at the UMKC School of Medicine. The gift comes from the estate of the late Mary K. Geldmacher, a retired St. Louis school teacher who suffered from pulmonary fibrosis and passed away in 2009. Pulmonary fibrosis is the formation or development of excess fibrous connective tissue in the lungs, commonly described as “scarring of the lung.”

26 Apr 2012

Helpful roles of rank, toxic substances

Usually, we think of mold, feces, nitric oxide, hydrogen sulfide and rat poison as rank, toxic or both. But scientists funded by the National Institutes of Health are learning more about the helpful roles these substances can play.

26 Apr 2012

Active cognitive lifestyle lowers risk for dementia

The findings of a new study suggest that the protective effects of an active cognitive lifestyle arise through multiple biological pathways.

26 Apr 2012

Physical activity reduces oxidative stress in people with SCT

Sickle cell disease (SCD), an inherited condition that causes red blood cells to sometimes deform into a crescent shape, affects an estimated 100,000 Americans, typically those of African descent. However, far more have sickle cell trait (SCT), caused when individuals carry just a single copy of the disease-causing mutation in their genes.

26 Apr 2012

Kv7.4 channels may play a fundamental role in high blood pressure

Scientists have identified what could be a biological tipping point in the development of high blood pressure, in a discovery that could one day lead to new treatment.

26 Apr 2012

Study sheds light on how stress differently affects women’s hearts

Coronary artery disease continues to be a major cause of death in the U.S., killing hundreds of thousands of people per year. However, this disease burden isn't evenly divided between the sexes; significantly more men than women are diagnosed with coronary artery disease each year. The reasons behind this difference aren't well defined. Though some studies have shown that men's hearts become more constricted than women's during exercise, letting less blood flow through, women are more likely than men to have symptoms of heart trouble after emotional upsets.

25 Apr 2012

Nordion announces additional TheraSphere Phase III trial for HCC

Nordion Inc., a leading provider of products and services for the prevention, diagnosis and treatment of disease, today announced an additional randomized, multi-centre Phase III clinical trial for TheraSphere, Nordion's yttrium-90 (Y-90) glass microsphere treatment for liver cancer.

24 Apr 2012

New device can correct bone deformities in children

Another day, another four turns of the screw. That's just a part of life for people, primarily children, undergoing the long and difficult process of distraction osteogenesis, a method to correct bone deformities that leave one limb shorter than the other.

24 Apr 2012

‘Brain freeze’ provides clue to migraine cause and therapy

According to latest reports by researchers the headache that is caused by eating something cold like an ice cream, may be caused by a sudden change in brain blood flow. The U.S. team of researchers add that this study may show targets to treat other, more troubling forms of headache such as migraine.

23 Apr 2012