Biochemistry News and Research

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UH launches careers of 5 NSF Graduate Research Fellows for 2011

The University of Houston (UH) launched the graduate careers of five National Science Foundation (NSF) Graduate Research Fellows for 2011. Recognizing outstanding students pursuing research-based master's and doctoral degrees in NSF-supported science, technology, engineering and mathematics disciplines, the three-year fellowships cover tuition and include a $30,000 annual stipend.

21 May 2011

DFG to fund 60 million euros for 18 new Research Training Groups

With the aim of further strengthening early-career research in Germany, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish 18 new Research Training Groups.

21 May 2011

Antibodies produced in space less effective than those produced on terra firma

The trip to Mars just got a little more difficult now that French researchers have discovered that antibodies used to fight off disease might become seriously compromised during long-term space flight. In a new report published online in the FASEB Journal, the scientists show that antibodies produced in space are less effective than those produced on terra firma.

21 May 2011

Researchers uncover new details of unusual biological mechanism in brains of diverse species

Researchers at the University of California, San Diego School of Medicine have uncovered new details of an unusual biological mechanism in the brains of diverse species that not only helps regulate how their brains develop, but also how they function later in life. The discovery could lead to new biomarkers for specific neurological diseases in humans and, possibly, the development of drugs to cure them.

21 May 2011

Berkeley Lab scientists reveal how protein-making machine bends without breaking

It sounds like hype from a late-night infomercial: It can twist and bend without breaking! And wait, there's more: It could someday help you fend off disease!

20 May 2011

GIS discovery could help generate stem cells more efficiently for biomedical applications

A team of scientists from Genome Institute of Singapore (GIS) of the Agency for Science, Technology and Research (A*STAR) have shown how proteins involved in controlling genes work together to carry out their functions in stem cells and demonstrated for the very first time, how they can change interaction partners to make other types of cells.

20 May 2011

Sensitive troponin assays improve clinical outcome and cardiac patient management

Research presented this week at the International Federation of Clinical Chemistry Congress and Laboratory Medicine showed that using a lower diagnostic threshold for troponin improves clinical outcomes and patient survival in patients with suspected acute coronary syndromes.

19 May 2011

Scientists identify key protein behind drug-resistant leukemia

Acute lymphoblastic leukemia, or ALL, is the most common form of childhood cancer. While most children treated for this disease survive, in a subgroup of patients the disease does not respond to treatment.

19 May 2011

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Mosquitoes are becoming more resistant to current pesticides. That's troubling to Kansas State University biologist Kristin Michel, as it means malaria and other mosquito-borne diseases will continue spreading. A recent grant from the National Institutes of Health may change all that.

18 May 2011

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Researchers at the University of Texas Medical Branch at Galveston and the University of California-San Diego School of Medicine have published a study that offers a new understanding of a protein critical to physiological processes involved in major diseases such as diabetes and cancer. This work could help scientists design drugs to battle these disorders.

18 May 2011

Over-activation of single gene promotes leukemia, but its loss causes liver cancer

An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in the development of leukemia also acts to prevent cancer of the liver.

17 May 2011

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Mount Sinai School of Medicine and Pacific Biosciences of California, Inc. announced a bi-coastal collaboration to advance clinical research through the Mount Sinai Institute for Genomics and Multiscale Biology to be led by Eric E. Schadt, Ph.D.

16 May 2011

Computationally designed antiviral proteins may fight against influenza

A research article May 12 in Science demonstrates the use of computational methods to design new antiviral proteins not found in nature, but capable of targeting specific surfaces of flu virus molecules.

16 May 2011

McGill research team finds distinct disease-causing mutations and saves baby girl

About two years ago, Dr. Philippe Gros, a McGill University professor in the Department of Biochemistry and a Principal Investigator in thd McGill Life Sciences Complex, described a mouse mutant that was immunodeficient and hypersensitive to the Bacille Calmette-Gu-rin (BCG) vaccine and to tuberculosis (TB).

12 May 2011

Researchers help explain why smart drugs are not effective in some cancer patients

Some of the most effective and expensive cancer drugs, dubbed "smart drugs" for their ability to stop tumors by targeting key drivers of cancer cell growth, are not effective in some patients. In two related studies, Yale School of Medicine researchers examined one such driver, the EGF receptor, and found that a decoy receptor might be limiting the amount of drug that gets to the intended target.

12 May 2011

Novel two-drug combination cures young patient with extensively drug-resistant tuberculosis

Belgian physicians report they have cured a young patient with extensively drug-resistant tuberculosis (XDR-TB) using a novel two-drug combination developed by researchers at Albert Einstein College of Medicine of Yeshiva University. The report, published in the Pediatric Infectious Disease Journal, marks the first known clinical use of this treatment for XDR-TB, the most deadly form of the disease.

11 May 2011

Long non-coding RNA promotes melanoma cell survival and invasion

Traditionally, RNA was mostly known as the messenger molecule that carries protein-making instructions from a cell's nucleus to the cytoplasm. But scientists now estimate that approximately 97 percent of human RNA doesn't actually code for proteins at all. A flurry of research in the past decade has revealed that some types of non-coding RNAs switch genes on and off and influence protein function.

11 May 2011

UH chemist receives prestigious Sloan award for next-generation computer memory

Investigating the building blocks for next-generation computer memory has earned a University of Houston chemist his third Tier One research award.

10 May 2011

Scientists decipher genome of tropical marine organism

An international team of researchers led by scientists at Scripps Institution of Oceanography at UC San Diego has deciphered the genome of a tropical marine organism known to produce substances potentially useful against human diseases.

10 May 2011

UCSF scientists receive CIRM grants to advance degenerative muscle disease research

Three UCSF scientists have received grants from the California Institute for Regenerative Medicine to advance their investigations of treatment strategies for degenerative muscle diseases, such as muscular dystrophy, and heart disease, and to determine why human embryonic stem cells are susceptible to forming tumors.

10 May 2011

Biochemistry News and Research

UH launches careers of 5 NSF Graduate Research Fellows for 2011

DFG to fund 60 million euros for 18 new Research Training Groups

Antibodies produced in space less effective than those produced on terra firma

Researchers uncover new details of unusual biological mechanism in brains of diverse species

Berkeley Lab scientists reveal how protein-making machine bends without breaking

GIS discovery could help generate stem cells more efficiently for biomedical applications

Sensitive troponin assays improve clinical outcome and cardiac patient management

Scientists identify key protein behind drug-resistant leukemia

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Over-activation of single gene promotes leukemia, but its loss causes liver cancer

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Computationally designed antiviral proteins may fight against influenza

McGill research team finds distinct disease-causing mutations and saves baby girl

Researchers help explain why smart drugs are not effective in some cancer patients

Novel two-drug combination cures young patient with extensively drug-resistant tuberculosis

Long non-coding RNA promotes melanoma cell survival and invasion

UH chemist receives prestigious Sloan award for next-generation computer memory

Scientists decipher genome of tropical marine organism

UCSF scientists receive CIRM grants to advance degenerative muscle disease research

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