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Researchers study zebrafish embryo skin to find link between low calcium and colon cancer

A tiny, transparent fish embryo and a string of surprises led scientists to a deeper understanding of the perplexing link between low calcium and colon cancer.

14 Dec 2013

Penn researchers identify protein that could clear Alzheimer's plaques

The body is structured to ensure that any invading organisms have a tough time reaching the brain, an organ obviously critical to survival. Known as the blood-brain barrier, cells that line the brain and spinal cord are tightly packed, making it difficult for anything besides very small molecules to cross from the bloodstream into the central nervous system. While beneficial, this blockade also stands in the way of delivering drugs intended to treat neurological disorders, such as Alzheimer's.

9 Dec 2013

New genetics promises to change faulty genes of future generations by using "designer sperm”

Bethesda, MD-Get ready: The "new genetics" promises to change faulty genes of future generations by introducing new, functioning genes using "designer sperm." A new research report appearing online in The FASEB Journal, shows that introducing new genetic material via a viral vector into the sperm of mice leads to the presence and activity of those genes in the resulting embryos.

3 Dec 2013

Researchers identify critical mechanism to improve survival and behavior of new brain cells

A specialized type of brain cell that tamps down stem cell activity ironically, perhaps, encourages the survival of the stem cells' progeny, Johns Hopkins researchers report.

11 Nov 2013

Linkam Scientific Instruments report the use of CMS196 for the imaging of mammalian cells at the London Research Institute, Cancer Research UK

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their innovative CMS196 cryo stage for the study of mammalian cells at the London Research Institute, Cancer Research UK.

From Linkam Scientific Instruments 5 Nov 2013

Researchers explore the origin of sweat gland stem cells

Without sweat, we would overheat and die. In a recent paper in the journal PLOS ONE, USC faculty member Krzysztof Kobielak and a team of researchers explored the ultimate origin of this sticky, stinky but vital substance - sweat gland stem cells.

24 Oct 2013

Whitehead Institute scientists discover insidious nature of influenza virus

Revealing influenza's truly insidious nature, Whitehead Institute scientists have discovered that the virus is able to infect its host by first killing off the cells of the immune system that are actually best equipped to neutralize the virus.

21 Oct 2013

Newly discovered compound could be developed as antifungal drug to treat fungal infections

On a molecular level, you have more in common with shower curtain mold or the mushrooms on your pizza than you might think. Humans and fungi share similar proteins, a biological bond that makes curing fungal infections difficult and expensive.

7 Oct 2013

Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

Overexpression of cytoglobin gene inhibits hypoxic injury to neuroblastoma cells

Cytoglobin is a temporary oxygen reservoir, which might provide a minimal, but continuous supply of intracellular oxygen during ischemic and anoxic conditions.

17 Sep 2013

Researchers develop new imaging technique to study function of entire nervous systems

A major aim of today's neuroscience is to understand how an organism's nervous system processes sensory input and generates behavior. To achieve this goal, scientists must obtain detailed maps of how the nerve cells are wired up in the brain, as well as information on how these networks interact in real time.

10 Sep 2013

UCSF scientists identify new way to manipulate immune system from autoimmune diseases

Scientists from UC San Francisco have identified a new way to manipulate the immune system that may keep it from attacking the body-s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.

10 Sep 2013

Research findings raise hope for new heart therapies

Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center recently found hope in an unlikely source - stem cells in cortical, or compact, bone.

5 Sep 2013

Researchers make significant step in understanding and imaging protein synthesis

Researchers at Columbia University, in collaboration with biologists in Baylor College of Medicine, have made a significant step in understanding and imaging protein synthesis, pinpointing exactly where and when cells produce new proteins.

26 Aug 2013

LMU immunologists develop new technique to fight against tumors, autoimmune diseases

Immunologists at Ludwig-Maximilians-Universitaet (LMU) in Munich have come up with a new technique that can be used both to fight tumors and to treat autoimmune diseases. A new grant from the Federal Ministry for Education and Research will enable the method to be developed further.

14 Aug 2013

High-tech laser technique offers control of gene therapy and genetic engineering method

The applications of gene therapy and genetic engineering are broad: everything from pet fish that glow red to increased crop yields worldwide to cures for many of the diseases that plague humankind.

8 Aug 2013

Researchers create calcium-sensitive proteins that respond quickly to changes in neuron activity

Princeton University researchers have created "souped up" versions of the calcium-sensitive proteins that for the past decade or so have given scientists an unparalleled view and understanding of brain-cell communication.

26 Jul 2013

Cochlear implants restore usable hearing to deaf patients

Cochlear implants, electrical prosthetic devices that stimulate inner ear neurons of individuals who have lost their cochlear sensory cells, restore usable hearing to deaf patients. Cochlear implant electrodes are placed in the fluid-filled scala tympani of the cochlea, at a significant distance from the spiral ganglion and even from the spiral ganglion dendrites.

22 Jul 2013

Researchers monitor dynamic cellular events that take place during cardiac regeneration in zebrafish

In a study published in the June 19 online edition of the journal Nature, a scientific team led by researchers from the University of California, San Diego School of Medicine visually monitored the dynamic cellular events that take place when cardiac regeneration occurs in zebrafish after cardiac ventricular injury. Their findings provide evidence that various cell lines in the heart are more plastic, or capable of transformation into new cell types, than previously thought.

20 Jun 2013

Scientists create way to see structures that store memories in living brain

Oscar Wilde called memory "the diary that we all carry about with us." Now a team of scientists has developed a way to see where and how that diary is written.