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New analysis highlights growing trends in combination cancer therapy clinical trials

The Cancer Research Institute, a nonprofit organization dedicated to the discovery and development of powerful immunotherapies for all types of cancer, announced today the publication of its newest analysis of the global landscape of clinical development of drugs that target the PD1/PDL1 immune checkpoint pathway.

10 Feb 2022

Study reveals a significant gap in disadvantaged children’s financial skills

The financial skills of 15-year-olds from socio-economically disadvantaged backgrounds are similar to 11-year-olds from the most advantaged backgrounds, shows a new report by UCL researchers.

10 Feb 2022

New rapid, cheaper test could help advance personalized cancer treatment

Using a routine blood sample, investigators have developed an extremely sensitive assay to detect and quantify DNA fragments containing rare genetic mutations in a patient's cancer cells.

10 Feb 2022

Nine new Discovery Grants awarded to fuel the development of ALS treatments

With promising new therapies for amyotrophic lateral sclerosis (ALS) on the horizon, now is the time for ongoing investment in research discovery that will continue to fuel the development of treatments.

10 Feb 2022

High levels of body fat in men linked to lower bone density and increased risk for osteoporosis

Men with high levels of body fat have lower bone density and may be more likely to break a bone than those with normal levels of body fat, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

10 Feb 2022

Survey shows increase in human exposure to potentially harmful pesticide

One out of three people in a large survey showed signs of exposure to a pesticide called 2,4-D, according to a study published today by researchers at the George Washington University.

10 Feb 2022

KHN’s ‘What the Health?’: FDA takes center stage

The FDA is still lacking a Senate-confirmed leader, but the agency is at the center of several major policy battles. Lawmakers this year must renew the bill that authorizes drug companies to pay "user fees," which enable the agency to hire additional reviewers to speed the approval of drugs.

10 Feb 2022

Study suggests SARS-CoV-2 Omicron showed increased household transmission and immune evasion in Norway

Researchers from Norway used contact tracing data to measure and compare the household secondary attack rate of the SARS-CoV-2 Omicron and Delta variants at a time of prominence of both variants in the country.

10 Feb 2022

Study reports accumulation of SARS-CoV-2 RNA in sewer biofilms

During the COVID-19 pandemic, monitoring the levels of SARS-CoV-2 RNA in wastewater entering treatment plants has been one way that researchers have gauged the disease's spread.

10 Feb 2022

Analysis reveals the prevalence of loneliness at a problematic level in 113 countries

Loneliness at a problematic level is widespread in many countries, finds an analysis of evidence from 113 countries and territories during 2000-19 published by The BMJ today.

10 Feb 2022

Excess COVID-19 mortality in Eastern Europe linked to lower vaccination rates and weak implementation of regulations

Researchers assessed the association between excess COVID-19 mortalities with vaccination rate, and regulation enforcement, in Eastern European countries that witnessed high COVID-19 mortalities throughout 2021.

10 Feb 2022

Study: Almost a third of older adults infected with covid-19 develop new conditions

Almost a third (32 of every 100) of older adults infected with covid-19 in 2020 developed at least one new condition that required medical attention in the months after initial infection, 11 more than those who did not have covid-19, finds a US study published by The BMJ today.

10 Feb 2022

Potential new diagnostic marker for ulcerative colitis discovered

An international research collaboration has discovered a potential new diagnostic marker for ulcerative colitis in a trans-ethnic analysis of Japanese and white patients.

10 Feb 2022

Development of QCC-targeting therapeutic agents may lead to new cancer treatments

Announcing a new review article publication for Acta Materia Medica journal. Quiescent cancer cells (QCCs) reversibly reside in G0 phase, thus allowing them to survive chemotherapy and radiotherapy, which generally target proliferating cells.

10 Feb 2022

New research confirms the safety of mRNA COVID-19 vaccines for people with cancer

New research in the February 2022 issue of JNCCN—Journal of the National Comprehensive Cancer Network confirms that mRNA vaccine for COVID-19 are just as safe for people with cancer as they are for cancer-free individuals.

10 Feb 2022

Study provides new understanding of caffeine's protective effects on the cardiovascular system

Scientists have a new understanding of the protective effects of caffeine on the cardiovascular system. While its stimulant effects have long been characterized, a team of Canadian researchers have discovered how caffeine interacts with key cellular factors to remove cholesterol from the bloodstream.

10 Feb 2022

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Researchers investigated the efficacy of two multi-kinase inhibitors, olverembatinib and ponatinib, in inhibiting SARS-CoV-2 omicron-mediated cytokine release in human peripheral blood mononuclear cells.

10 Feb 2022

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

In two recent studies, researchers at Washington University School of Medicine in St. Louis found evidence that the omicron variant of the virus that causes COVID-19 causes less severe disease than previous variants — at least in rodents — but that many antibody-based therapies may not be effective against it.

10 Feb 2022

Individuals with alcohol problems may have lower functional connectivity in brain regions that process emotions

People predisposed to heavy drinking and alcohol problems may have lower functional connectivity - the patterns of signaling between brain areas - in regions that process emotions and social situations.

10 Feb 2022

Measuring T cell responses to SARS-CoV-2 vaccination and infection in healthcare workers with two different assays

The purpose of this study was to compare the OI TSPOT with the in-house PITCH ELISpot for reporting T cell responses specific to SARS-CoV-2 spike and structural proteins.

10 Feb 2022

Research News and Research

New analysis highlights growing trends in combination cancer therapy clinical trials

Study reveals a significant gap in disadvantaged children’s financial skills

New rapid, cheaper test could help advance personalized cancer treatment

Nine new Discovery Grants awarded to fuel the development of ALS treatments

High levels of body fat in men linked to lower bone density and increased risk for osteoporosis

Survey shows increase in human exposure to potentially harmful pesticide

KHN’s ‘What the Health?’: FDA takes center stage

Study suggests SARS-CoV-2 Omicron showed increased household transmission and immune evasion in Norway

Study reports accumulation of SARS-CoV-2 RNA in sewer biofilms

Analysis reveals the prevalence of loneliness at a problematic level in 113 countries

Excess COVID-19 mortality in Eastern Europe linked to lower vaccination rates and weak implementation of regulations

Study: Almost a third of older adults infected with covid-19 develop new conditions

Potential new diagnostic marker for ulcerative colitis discovered

Development of QCC-targeting therapeutic agents may lead to new cancer treatments

New research confirms the safety of mRNA COVID-19 vaccines for people with cancer

Study provides new understanding of caffeine's protective effects on the cardiovascular system

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

Individuals with alcohol problems may have lower functional connectivity in brain regions that process emotions

Measuring T cell responses to SARS-CoV-2 vaccination and infection in healthcare workers with two different assays

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