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CEL-SCI receives Polish government approval to commence Multikine Phase III clinical trial in head, neck cancer

CEL-SCI Corporation announced today that it has received approval to begin enrollment of patients in its Phase III clinical trial of Multikine® from the Polish Minister of Health. This approval marks a very important milestone, namely that all nine countries in the study have now given official government approval. Five of about 48 clinical centers for this global trial will be located in Poland.

5 May 2011

Researchers discover new mechanism by which BRCA1 gene mutations can induce breast cancer

Two researchers from the Centre for Genomic Regulation in Barcelona have discovered a new mechanism by which mutations in gene BRCA1 can induce breast cancer.

5 May 2011

Selexys begins patient enrollment in SelG1 Phase I study for sickle cell disease

Selexys Pharmaceuticals announced today that it has initiated enrollment in a Phase I clinical study of its lead compound, SelG1, a humanized anti-P-selectin antibody.

5 May 2011

Researchers identify regulatory protein that can inhibit cancer metastasis

A protein capable of halting the spread of breast cancer cells could lead to a therapy for preventing or limiting the spread of the disease.

5 May 2011

Top 10 gadget gifts for Mother's Day 2011

ElderGadget.com, the only website devoted to news, reviews, and information on the hottest consumer electronics with senior-friendly features, announces its top ten technology gifts for mom, sure to have a gadget she will find fun to own and easy to use.

From Garmin 4 May 2011

Breakthrough research offers hope for new obesity treatment

By knocking down the expression of a protein in rat brains known to stimulate eating, Johns Hopkins researchers say they not only reduced the animals' calorie intake and weight, but also transformed their fat into a type that burns off more energy. The finding could lead to better obesity treatments for humans, the scientists report.

4 May 2011

Scientists discover new mitochondria regulation mechanism

Scientists have discovered a new component of mitochondria that plays a key part in their function. The discovery, which is presented in the journal Cell Metabolism, is of potential significance to our understanding of both inherited and age-related diseases.

4 May 2011

Yale, Debiopharm partner to develop and commercialize Debio 1036 for inflammatory diseases

Debiopharm Group, a global biopharmaceutical development specialist that focuses on serious medical conditions and particularly oncology, and Yale University, a premier university with a long tradition of both basic and clinically directed biomedical research, announce an exclusive worldwide license agreement concerning the development and commercialization of Debio 1036, a first-in-class inhibitor for autoimmune and inflammatory diseases.

4 May 2011

Four medical centers enroll additional patients for NWBT's ongoing brain cancer trial

Northwest Biotherapeutics today announced that four medical centers across the country are actively recruiting and screening to enroll additional new patients in the Company's ongoing 240-patient randomized, double blind, placebo controlled clinical trial of DCVax immune therapy for Glioblastoma multiforme, the most lethal type of brain cancer.

4 May 2011

New book on the myth of junk DNA

Forty years ago scientists discovered that more than 95% of our DNA does not encode proteins. Since then the non-protein-coding portion was labeled "junk" and attributed to molecular accidents that have accumulated in the course of evolution.

4 May 2011

New nano-vault delivery system can fight cancer

UCLA scientists have discovered a way to wake up the immune system to fight cancer by delivering an immune system-stimulating protein in a nanoscale container called a vault directly into lung cancer tumors, harnessing the body's natural defenses to fight disease growth.

4 May 2011

New MIT drug-delivery nanoparticle could target any type of tumor

MIT chemical engineers have designed a new type of drug-delivery nanoparticle that exploits a trait shared by almost all tumors: They are more acidic than healthy tissues.

4 May 2011

Fat stem cells may help develop new regenerative therapies for cardiovascular disease

Stem cells extracted from body fat may pave the way for the development of new regenerative therapies including soft tissue reconstruction following tumor removal or breast mastectomy surgery, the development of tissue-engineered cartilage or bone, and the treatment of cardiovascular disease.

4 May 2011

FibroGen announces proof-of-principle for FG-4592 Phase 2 study in hemodialysis patients

FibroGen, Inc., today announced proof-of-principle for oral anemia therapy FG-4592, a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor, in end-stage renal disease patients receiving hemodialysis.

4 May 2011

Invention of optogenetics sheds light on how brain works

Commenting on Edward Boyden's article, Ben Barres, Head of the Neuronal & Glial Cell Biology Section of Faculty of 1000 and Professor at Stanford University School of Medicine said: "There will probably be a Nobel prize for optogenetics someday as it has revolutionized our attempts to understand how the brain works. This article provides a fascinating insight into the birth of optogenetics and the roles of the major players."

4 May 2011

Fat-loss leads to earlier death in mice

Since the 1930s scientists have proposed food restriction as a way to extend life in mice. Though feeding a reduced-calorie diet has indeed lengthened the life spans of mice, rats and many other species, new studies with dozens of different mouse strains indicate that food restriction does not work in all cases.

4 May 2011

SARcode reports encouraging data from SAR 1118 Phase 2 dry eye trial

SARcode Corporation presented data today for their lead investigational molecule, SAR 1118. In a Phase 2 dry eye trial, subjects receiving SAR 1118 demonstrated a reduction in corneal staining, increased tear production, and improved visual-related function as compared to placebo. These data were part of the scientific program of the Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting held in Fort Lauderdale, Florida.

4 May 2011

Top-line results from Lymphoseek NEO3-09 Phase 3 study in breast cancer, melanoma

Neoprobe Corporation, a diversified developer of innovative oncology diagnostic products, today announced top-line results from its Lymphoseek NEO3-09 study.

4 May 2011

Viewpoints: Dem representatives on health spending; Star Tribune praises IPAB; NY Times on stem cells

When the debate over the fiscal 2012 budget began, the country — or, more accurately, the media — was focused on Rep. Paul Ryan's proposal. Introduced on behalf of the Republican House majority, our colleague's plan puts the interests of wealthy corporations first by slashing Medicare and Medicaid and spending trillions on a new corporate tax cut. Indeed, cutting is all it seems to do. ... That's not a jobs plan — that's an economic death sentence.

4 May 2011

WWP2 protein appears to play a key role in tumor survival

A protein known as WWP2 appears to play a key role in tumor survival, a research team headed by a scientist at The University of Texas MD Anderson Cancer Center reports in an advance online publication of Nature Cell Biology.

4 May 2011

Cell News and Research

CEL-SCI receives Polish government approval to commence Multikine Phase III clinical trial in head, neck cancer

Researchers discover new mechanism by which BRCA1 gene mutations can induce breast cancer

Selexys begins patient enrollment in SelG1 Phase I study for sickle cell disease

Researchers identify regulatory protein that can inhibit cancer metastasis

Top 10 gadget gifts for Mother's Day 2011

Breakthrough research offers hope for new obesity treatment

Scientists discover new mitochondria regulation mechanism

Yale, Debiopharm partner to develop and commercialize Debio 1036 for inflammatory diseases

Four medical centers enroll additional patients for NWBT's ongoing brain cancer trial

New book on the myth of junk DNA

New nano-vault delivery system can fight cancer

New MIT drug-delivery nanoparticle could target any type of tumor

Fat stem cells may help develop new regenerative therapies for cardiovascular disease

FibroGen announces proof-of-principle for FG-4592 Phase 2 study in hemodialysis patients

Invention of optogenetics sheds light on how brain works

Fat-loss leads to earlier death in mice

SARcode reports encouraging data from SAR 1118 Phase 2 dry eye trial

Top-line results from Lymphoseek NEO3-09 Phase 3 study in breast cancer, melanoma

Viewpoints: Dem representatives on health spending; Star Tribune praises IPAB; NY Times on stem cells

WWP2 protein appears to play a key role in tumor survival

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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