Vascular News and Research

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No overall survival benefit for bevacizumab in ovarian cancer

Addition of bevacizumab to first-line platinum-based chemotherapy does not improve overall survival in women with ovarian cancer, according to the mature data of the ICON7 trial.

26 Jun 2015

Study: Cellular respiration separates effects of bactericidal and bacteriostatic antibiotics

Antibiotics are the mainstay in the treatment of bacterial infections, and together with vaccines, have enabled the near eradication of infectious diseases like tuberculosis, at least in developed countries.

25 Jun 2015

Researchers advance stem cell therapy to block vision loss caused by diabetic retinopathy

University of Virginia School of Medicine researchers have taken a significant step forward in their efforts to use stem cells to block vision loss caused by diabetic retinopathy, a condition that affects millions of people with diabetes.

25 Jun 2015

ACT intervention may be effective in reducing risk for cardiovascular disease

A controlled study published in the current issue of Psychotherapy and Psychosomatic indicates the usefulness of a brief behavioral intervention targeting psychological risk factors for vascular disease.

24 Jun 2015

NIH awards $1.8 million grant for brain imaging technique

A researcher at the Cockrell School of Engineering at The University of Texas at Austin has received a four-year, $1.8 million grant from the National Institutes of Health (NIH) to develop a new technique for imaging blood flow across the surface of the brain that could help patients undergoing neurosurgery.

24 Jun 2015

Johns Hopkins scientists use experimental therapy to reverse progression of atherosclerosis in rodents

In what may be a major leap forward in the quest for new treatments of the most common form of cardiovascular disease, scientists at Johns Hopkins report they have found a way to halt and reverse the progression of atherosclerosis in rodents by loading microscopic nanoparticles with a chemical that restores the animals’ ability to properly handle cholesterol.

24 Jun 2015

Study reveals benefit of early screening for vascular disorder patent ductus arteriosus among preterm infants

Among extremely preterm infants, early screening for the vascular disorder patent ductus arteriosus before day 3 of life was associated with a lower risk of in-hospital death and pulmonary hemorrhage, but not with differences in other severe complications, according to a study in the June 23/30 issue of JAMA.

24 Jun 2015

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

A promising biomarker for the severity of age-related white matter changes (ARWMCs) and endothelial function was evaluated at Hiroshima University, Japan. The relationship between this biomarker, the telomeric 3'-overhang (G-tail) length, and cardiovascular risk in humans is unclear so far.

23 Jun 2015

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

Israeli researchers have successfully established a new approach for pacing the heart and synchronizing its mechanical activity without the use of a conventional electrical pacemaker. This novel biologic strategy employs light-sensitive genes that can be injected into the heart and then activated by flashes of blue light.

23 Jun 2015

Study: High-normal BP in young adults spells heart failure risk in later life

Mild elevations in blood pressure considered to be in the upper range of normal during young adulthood can lead to subclinical heart damage by middle age -- a condition that sets the stage for full-blown heart failure, according to findings of a federally funded study led by scientists at Johns Hopkins.

23 Jun 2015

Scientists explore diabetes-cognitive decline link across cultures

Diabetes is a known risk factor for cognitive decline and dementia, age-related conditions that affect memory and thinking skills. However, little is known about how the diabetes-cognitive decline link compares across cultures.

23 Jun 2015

Edwards Lifesciences announces FDA approval of SAPIEN 3 transcatheter aortic heart valve

Edwards Lifesciences Corporation, the global leader in the science of heart valves and hemodynamic monitoring, today announced U.S. Food and Drug Administration approval of its most advanced transcatheter aortic heart valve – the Edwards SAPIEN 3 valve with the Commander Delivery System – for the treatment of high-risk patients suffering from severe, symptomatic aortic stenosis.

18 Jun 2015

New study reports more practical approach to heal the heart after a heart attack

Stem cell have been the main focus of healing therapy research because they can morph into new cells, and using a patient's own stem cells will not induce an autoimmune response. For healing after a heart attack, the ideal time to administer these therapies is when reopening the clogged blood vessel because the heart is easily accessible. While stem cells show promise for heart attack treatment, the process of harvesting and reintroducing the cells—which can take days or weeks—is too slow for this window.

17 Jun 2015

New DARPA grant supports Wyss Institute project that aims to fight gastrointestinal illness

For decades, American travelers to international destinations have been plagued by acute gastrointestinal illnesses that can arise from travel to other countries. The Center for Disease Control warns that depending on the destination, between 30 to 70 percent of travelers can expect to experience gastrointestinal distress from ingesting foreign or pathogenic bacteria that can be present in poorly sanitized water or food.

17 Jun 2015

FDA grants Fast Track designation to Juventas' JVS-100 drug candidate and allows Phase 2b clinical trial

Juventas Therapeutics, Inc., a clinical-stage biotechnology company developing novel non-viral gene therapies that activate natural processes to repair the body, today announced that its product candidate, JVS-100, received Fast Track designation from the U.S. Food and Drug Administration for the treatment of advanced ischemic chronic heart failure.

16 Jun 2015

Study explores role of ALK1 protein in breast cancer metastasis

Pietras said that although prognosis for breast cancer is relatively good when detected in its early stages, metastatic disease is the cause of 90 percent of all cancer-related deaths. Therefore, learning more about the metastatic process and finding new cures to inhibit disease spread is at the center of clinical attention.

15 Jun 2015

Brain changes reflect higher risk of cerebrovascular disease in women who experience more hot flashes

Women who experience more hot flashes, particularly while sleeping, during the menopause transition are more likely to have brain changes reflecting a higher risk for cerebrovascular disease, such as stroke and other brain blood flow problems, according to a pilot study led by researchers at the University of Pittsburgh School of Medicine published online today in Menopause and funded by the National Institutes of Health.

11 Jun 2015

Star-shaped brain cells control cerebral blood flow and blood pressure

A star-shaped brain cell called an astrocyte appears to help keep blood pressure and blood flow inside the brain on a healthy, even keel, scientists report.

10 Jun 2015

Dietary data used by U.S. Government's 2015 DGAC is scientifically flawed, claim health researchers

U.S. government-issued dietary recommendations continue to evolve over time. In a special article published in Mayo Clinic Proceedings, an obesity theorist and cardiovascular health researchers claim that the main source of dietary information used by the U.S. Government's 2015 Dietary Guidelines Advisory Committee (DGAC) is scientifically flawed because the underlying data are primarily informed by memory-based dietary assessment methods (M-BMs) (eg, interviews and surveys).

10 Jun 2015

Stemedica receives FDA's IND approval for itMSC Phase IIa clinical trial to treat Alzheimer's disease

Stemedica Cell Technologies, Inc. received the FDA's investigational new drug (IND) approval for a United States-based, Phase IIa clinical study using its allogeneic stem-cell therapy to treat subjects with mild to moderate dementia due to Alzheimer's disease (AD), the sixth leading cause of death in the United States.

9 Jun 2015

Vascular News and Research

No overall survival benefit for bevacizumab in ovarian cancer

Study: Cellular respiration separates effects of bactericidal and bacteriostatic antibiotics

Researchers advance stem cell therapy to block vision loss caused by diabetic retinopathy

ACT intervention may be effective in reducing risk for cardiovascular disease

NIH awards $1.8 million grant for brain imaging technique

Johns Hopkins scientists use experimental therapy to reverse progression of atherosclerosis in rodents

Study reveals benefit of early screening for vascular disorder patent ductus arteriosus among preterm infants

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

Study: High-normal BP in young adults spells heart failure risk in later life

Scientists explore diabetes-cognitive decline link across cultures

Edwards Lifesciences announces FDA approval of SAPIEN 3 transcatheter aortic heart valve

New study reports more practical approach to heal the heart after a heart attack

New DARPA grant supports Wyss Institute project that aims to fight gastrointestinal illness

FDA grants Fast Track designation to Juventas' JVS-100 drug candidate and allows Phase 2b clinical trial

Study explores role of ALK1 protein in breast cancer metastasis

Brain changes reflect higher risk of cerebrovascular disease in women who experience more hot flashes

Star-shaped brain cells control cerebral blood flow and blood pressure

Dietary data used by U.S. Government's 2015 DGAC is scientifically flawed, claim health researchers

Stemedica receives FDA's IND approval for itMSC Phase IIa clinical trial to treat Alzheimer's disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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