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Researchers uncover insights into rare genetic disorders

Researchers studying rare genetic disorders have uncovered insights into those diseases in biological structures that regulate chromosomes when cells divide. Focusing on the cohesin complex, a group of proteins forming a bracelet that encircles chromosome pairs, scientists have discovered mutations that disrupt cohesin, causing a recently recognized class of diseases called cohesinopathies.

30 May 2012

Childhood obesity risk linked to delivery method

Delivery by cesarean section may double the risk for childhood obesity compared with vaginal delivery, show US study findings.

30 May 2012

FRAX tool ‘resistant’ to osteoporosis treatment effects

Osteoporosis therapy does not invalidate the use of the World Health Organization’s fracture risk assessment system for fracture prediction, study findings indicate.

30 May 2012

Doctors may predict girls at increased risk of eating disorders based on food choices

Doctors may be able to predict which girls are at risk of developing eating disorders based on the food choices they make when they are younger, according to a new study by Cincinnati Children's Hospital Medical Center.

30 May 2012

Hard work of GPs pays off: high levels of patient satisfaction reported

Commenting on the publication of the 'Patient Experience Survey of GP and Local NHS Services 2011/12' results, Dr Dean Marshall, Chair of BMA Scotland’s General Practice Committee said:

30 May 2012

Laboratory middleware solution to be exhibited by NoemaLife at this year’s AACC

NoemaLife, Europe’s leading provider of clinical and hospital software solutions, will exhibit the company’s HALIA middleware for clinical chemistry, microbiology and molecular biology labs at this year’s AACC (American Association of Clinical Chemists) Annual Meeting (15-19 July 2012, Los Angeles, CA).

30 May 2012

Death prediction for patients with pneumonia and raised glucose levels

Raised blood sugar (glucose) levels on admission to hospital can predict deaths in patients with community acquired pneumonia but without pre-existing diabetes, finds a study published on bmj.com today.

30 May 2012

Patients with history of skin infection more likely to develop surgical site infections

Johns Hopkins scientists have engineered cells that behave like AND and OR Boolean logic gates, producing an output based on one or more unique inputs. This feat, published in the May issue of Nature Chemical Biology, could eventually help researchers create computers that use cells as tiny circuits.

30 May 2012

New imaging device can better diagnose chronic ear infections

Doctors can now get a peek behind the eardrum to better diagnose and treat chronic ear infections, thanks to a new medical imaging device invented by University of Illinois researchers. The device could usher in a new suite of non-invasive, 3-D diagnostic imaging tools for primary-care physicians.

30 May 2012

Patients with mental health issues overwhelm ERs

Patients suffering from schizophrenia, psychotic tendencies and suicidal behaviors are burdening hospital ERs, reports Modern Healthcare.

30 May 2012

Mass. Eye and Ear Cataract Master bridges gap between wet lab training and patient surgery

Phacoemulsification cataract surgery is one of the most frequently performed eye surgeries in the United States, with 1.5 million procedures performed each year. It is also one of the most complex procedures to learn. A new, highly innovative, computer-based simulation tool, the Mass. Eye and Ear Cataract Master, bridges the learning gap that residents and ophthalmologists new to phaco must navigate prior to performing actual surgery.

30 May 2012

CHOC Children's research project receives $5.5M CIRM grant

A CHOC Children's research project, under the direction of Philip H. Schwartz, Ph.D., senior scientist at the CHOC Children's Research Institute and managing director of the facility's National Human Neural Stem Cell Resource, has been awarded a $5.5 million grant from the California Institute for Regenerative Medicine.

30 May 2012

Naphthalene exposure may increase risk of chromosomal aberrations in children

According to a new study, children exposed to high levels of the common air pollutant naphthalene are at increased risk for chromosomal aberrations (CAs), which have been previously associated with cancer. These include chromosomal translocations, a potentially more harmful and long-lasting subtype of CAs.

30 May 2012

Cabazitaxel offers added benefit for men with metastatic prostate cancer

Cabazitaxel has been approved since March 2011 in men with metastatic prostate cancer who no longer respond to conventional therapy with hormone blockers and have already been pre-treated with the cytostatic drug docetaxel.

30 May 2012

Scientists develop synthetic peptide that overcomes cancer cells’ survival defenses

Scientists at the Dana-Farber/Children's Hospital Cancer Center have developed an anti-cancer peptide that overcomes the stubborn resistance to chemotherapy and radiation often encountered in certain blood cancers when the disease recurs following initial treatment.

30 May 2012

NAC may be an effective therapy for some features of autism

A specific antioxidant supplement may be an effective therapy for some features of autism, according to a pilot trial from the Stanford University School of Medicine and Lucile Packard Children's Hospital that involved 31 children with the disorder.

30 May 2012

Secreted vesicles play role in spread of cancer

Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called "soil and seed" theory of 1889. New details that could help shed light on this hypothesis have been provided by a team of researchers from Weill Cornell Medical College, Memorial Sloan-Kettering Cancer Center, and their collaborators, proposing a new mechanism controlling cancer metastasis that offers fresh diagnostic and treatment potential.

29 May 2012

Neighborhood immunity has a role in determining risk of dengue infection

Researchers at the Johns Hopkins Bloomberg School of Public Health have found evidence of a role for neighborhood immunity in determining risk of dengue infection.

29 May 2012

Pre-exposure preventive treatment may be effective against suspected HIV

While immediate postexposure treatment for suspected HIV is critical, pre-exposure preventive treatment is a newer method that may be effective for people in high-risk groups, states a review of evidence published in CMAJ (Canadian Medical Association Journal).

29 May 2012

Oncos Therapeutics commences clinical study with oncolytic viruses

Oncos Therapeutics today announced the successful initiation of its Phase I clinical study of CGTG-102, an oncolytic adenovirus suggested as a potential new treatment for many types of solid tumors.

29 May 2012