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In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

A novel immunotherapy strategy using in vivo generation of transient engineered chimeric antigen receptor (CAR) T cells, through the delivery of modified mRNA, can reduce fibrosis and restore cardiac function in a mouse model of heart failure, researchers report.

6 Jan 2022

Researchers explore consequences of eroding norms over release of self-spreading viruses

Decades of research by generations of virologists have generally established that the use laboratory-modified self-spreading viruses is too unpredictable to be applied safely outside of contained facilities.

6 Jan 2022

Ocean living microbes make oxygen in the dark

There is more going on in the deep, dark ocean waters than you may think: Uncountable numbers of invisible microorganisms go about their daily lives in the water columns, and now researchers have discovered that some of them produce oxygen in an unexpected way.

6 Jan 2022

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

An experimental immunotherapy can temporarily reprogram patients' immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2022

Researchers study immune cell invasion process in living fruit fly embryos

To fight infections and heal injuries, immune cells need to enter tissue. They also need to invade tumors to fight them from within.

6 Jan 2022

More trusting societies achieve a faster decline in coronavirus infections and deaths

Countries where people have more trust in each other have been more successful in bringing down waves of coronavirus cases and deaths, a new study shows.

6 Jan 2022

Study estimates the global prevalence of dementia in 2050

The number of adults (aged 40 years and older) living with dementia worldwide is expected to nearly triple, from an estimated 57 million in 2019 to 153 million in 2050, due primarily to population growth and population aging.

6 Jan 2022

World renowned medical oncologist joins Henry Ford Cancer Institute

Internationally renowned medical oncologist Philip A. Philip, M.D., Ph.D., has joined Henry Ford Cancer Institute as director of Gastrointestinal Oncology and Neuroendocrine Oncology, medical director of Research and Clinical Care Integration, and co-leader of the Henry Ford Pancreatic Cancer Center.

6 Jan 2022

Maternal thyroid hormone levels during pregnancy may predict children's behavioral problems

Thyroid hormone levels during pregnancy may predict preschool boys' emotional and behavioral problems, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

6 Jan 2022

Study reinforces the link between microglia and some cases of brain disease

Certain subtle differences in DNA sequences are known to raise the chances a person may develop Alzheimer's or Parkinson's disease.

6 Jan 2022

Model of neuromuscular junction could accelerate new treatments for neuromuscular diseases

The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement.

6 Jan 2022

Some heart surgery patients may be able to control postoperative pain without opioids

Many patients who undergo heart surgery may be able to safely and effectively control postoperative pain without opioids after hospital discharge, according to research published online today in The Annals of Thoracic Surgery.

6 Jan 2022

Study finds a small, temporary menstrual change in women associated with COVID-19 vaccination

Women receiving one dose of a COVID-19 vaccine during a single menstrual cycle had an increase in cycle length of nearly one day, compared to unvaccinated women, according to a study funded by the National Institutes of Health.

6 Jan 2022

New study links anxiety and PTSD to increased myelin in brain's gray matter

A recent study links anxiety behavior in rats, as well as post traumatic stress disorder (PTSD) in military veterans, to increased myelin - a substance that expedites communication between neurons - in areas of the brain associated with emotions and memory.

6 Jan 2022

Researchers identify how a critical schistosomiasis drug works on the molecular level

Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.

6 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

Research may pave the way for designing new therapies to combat schistosomiasis

Neglected tropical diseases (NTDs) represent a group of about 20 conditions that affect more than a billion people worldwide.

6 Jan 2022

PLOS and CSHL expand partnership to offer new options for sharing preprints in medicine

The Public Library of Science (PLOS) and Cold Spring Harbor Laboratory (CSHL) today announced an expansion of their longstanding partnership to offer authors more options for rapidly and easily sharing their research before publication in a journal.

6 Jan 2022

Switching to smokeless tobacco associated with lower cardiovascular disease risk in smokers

Regular smokers are at heightened risk of developing cardiovascular disease, but crushing the butts in favor of a "smokeless" alternative like chewing tobacco, snuff or tobacco lozenges may go a long way toward bringing the danger down to a more normal level, a new UCLA-led study shows.

6 Jan 2022

WVU receives funding from National Eye Institute for retinal degeneration research

Inherited retinal degeneration can make even the most mundane tasks - like cooking, driving and walking down the sidewalk - difficult or impossible, and it can't be cured.

6 Jan 2022

Research News and Research

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

Researchers explore consequences of eroding norms over release of self-spreading viruses

Ocean living microbes make oxygen in the dark

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

Researchers study immune cell invasion process in living fruit fly embryos

More trusting societies achieve a faster decline in coronavirus infections and deaths

Study estimates the global prevalence of dementia in 2050

World renowned medical oncologist joins Henry Ford Cancer Institute

Maternal thyroid hormone levels during pregnancy may predict children's behavioral problems

Study reinforces the link between microglia and some cases of brain disease

Model of neuromuscular junction could accelerate new treatments for neuromuscular diseases

Some heart surgery patients may be able to control postoperative pain without opioids

Study finds a small, temporary menstrual change in women associated with COVID-19 vaccination

New study links anxiety and PTSD to increased myelin in brain's gray matter

Researchers identify how a critical schistosomiasis drug works on the molecular level

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Research may pave the way for designing new therapies to combat schistosomiasis

PLOS and CSHL expand partnership to offer new options for sharing preprints in medicine

Switching to smokeless tobacco associated with lower cardiovascular disease risk in smokers

WVU receives funding from National Eye Institute for retinal degeneration research

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