Research News and Research

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Omicron infection induces cross-reactive immune responses

New research revealed that vaccine-breakthrough infections might elicit cross-reactive bNAbs against all variants of concern.

31 Dec 2021

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

A new study used in silico approaches for designing a next-generation CD40-targeting vaccine, CD40.

31 Dec 2021

New technique combines bioprinting with cryopreservation to construct frozen structures

A new technique takes bioprinting - in which an ink of cells is printed, layer by layer, to form a structure - to a whole new, and icy level. Investigators from the Zhang lab at Brigham and Women's Hospital have developed a technology that they term "cryobioprinting," a method that uses a bioink embedded with cells to print frozen, complex structures that can be easily stored for later use.

31 Dec 2021

Microgravity likely to contribute to life-saving stem cell advances on Earth

The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells.

30 Dec 2021

Researchers warn about the dangers of vitamin B12 deficiency in people following plant-based diets

In the run up to Veganuary leading researchers are warning of the dangers of a quiet epidemic of vitamin B12deficiencyin people who follow increasingly popular plant-based diets.

30 Dec 2021

A reliable assessment of COVID-19 vaccine protection duration

Researchers from the University of North Carolina, University of Washington, and the US Food and Drug Administration propose fitting a Cox model with two time indexes, the event times measured from the start of the study in calendar time and the log hazard for the vaccine effect.

30 Dec 2021

How much do mutations reduce vaccine effectiveness in the Omicron variant?

In new research, scientists from Adaptive Biotechnologies have been investigating the impact of spike protein mutations on vaccine efficiency for the Omicron variant. The study is currently available on the medRxiv* preprint server while awaiting peer review.

30 Dec 2021

Loss of smell is the best predictor of COVID-19

A large international team of researchers has conducted a crowdsourced cross-sectional study, in which they have investigated the reliability of the olfactory loss (or loss of smell, or anosmia) as a predictor of coronavirus disease 19 (COVID-19).

30 Dec 2021

SARS-CoV-2 infection and immunity in pregnancy and fetal development

A review conducted by a team of researchers from the Icahn School of Medicine at Mount Sinai, the University of Colorado, and Active Motif, Incorporated compiles information on SARS-CoV-2 virology, in utero transmission from infected pregnant mothers to fetuses, new findings on possible methods of SARS-CoV-2 cellular trafficking through exosomes, and the transcriptomic effects of SARS-CoV-2 infection, in order to inform future studies aimed at a better understanding of COVID-19 and the development of therapeutic solutions against SARS-CoV-2.

30 Dec 2021

The use of monoclonal antibodies against infectious pathogens

Joshua Tan of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health wrote a review article in the journal DNA and Cell Biology about the role of monoclonal antibodies and briefly described a study on bispecific antibodies that neutralize SARS-CoV-2.

30 Dec 2021

Factors associated with SARS-CoV-2 breakthrough infection in fully vaccinated individuals

New study findings showed that the SARS-CoV-2 breakthrough infections are rare and show mild or asymptomatic profiles generally. The breakthrough infection occurs early after vaccination in almost 50% of the cases within 70 to 80 days post full vaccination.

30 Dec 2021

Reviewing myocarditis and pericarditis in immunosuppressed individuals following COVID-19 mRNA vaccination

A new study did not conclusively correlate the incidence of myocarditis or pericarditis with mRNA vaccination against SARS-CoV-2.

30 Dec 2021

Study explores relative reproduction of the SARS-CoV-2 omicron variant in South Africa

A new study, focused on the SARS-CoV-2 Omicron variant, presented a modeling result from an analysis of genome surveillance data in Gauteng province, South Africa, using an existing estimation technique.

30 Dec 2021

SUSU researchers identify biological indicators of long-lasting PTSD

War veterans have helped scientists of South Ural State University identify biological indicators which signal whether people have a post-traumatic stress disorder or a susceptibility to it.

30 Dec 2021

SARS-CoV-2 infection can produce self-attacking autoantibodies

Infection with the virus that causes COVID-19 can trigger an immune response that lasts well beyond the initial infection and recovery - even among people who had mild symptoms or no symptoms at all, according to Cedars-Sinai investigators.

30 Dec 2021

UK emergency aid to help vulnerable countries tackle the Omicron variant

Foreign Secretary Liz Truss has pledged up to £105 million of UK emergency aid to help vulnerable countries tackle the Omicron Covid-19 variant, with a particular focus on Africa.

30 Dec 2021

New test-to-stay approach enables kids and staffs to stay in school after COVID exposures

Children and staff who repeatedly test negative for COVID-19 after contact with someone who has the illness can safely remain in school if universal masking programs are in place, according to a new "test-to-stay" study report from the ABC Science Collaborative.

30 Dec 2021

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Drug-induced liver injury (DILI) is an adverse reaction to ingesting a drug, which can appear both in developmental stages, in their clinical use and even after being approved as a drug.

30 Dec 2021

Orphanhood decreases with the availability of antiretroviral therapy and male circumcision

Researchers at Columbia University Mailman School of Public Health found marked decreases in orphanhood particularly double orphanhood, among adolescents in Rakai, Uganda, corresponding with the availability of antiretroviral therapy (ART) beginning in 2004 and of male medical circumcision in 2007.

30 Dec 2021

Once-a-day antiretroviral medicine for children proven to be more effective at suppressing HIV

A once-a-day antiretroviral medicine that is low-cost and easy for children to take is also more effective at suppressing HIV than standard treatments, according to a global trial led by researchers at UCL.

30 Dec 2021

Research News and Research

Omicron infection induces cross-reactive immune responses

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

New technique combines bioprinting with cryopreservation to construct frozen structures

Microgravity likely to contribute to life-saving stem cell advances on Earth

Researchers warn about the dangers of vitamin B12 deficiency in people following plant-based diets

A reliable assessment of COVID-19 vaccine protection duration

How much do mutations reduce vaccine effectiveness in the Omicron variant?

Loss of smell is the best predictor of COVID-19

SARS-CoV-2 infection and immunity in pregnancy and fetal development

The use of monoclonal antibodies against infectious pathogens

Factors associated with SARS-CoV-2 breakthrough infection in fully vaccinated individuals

Reviewing myocarditis and pericarditis in immunosuppressed individuals following COVID-19 mRNA vaccination

Study explores relative reproduction of the SARS-CoV-2 omicron variant in South Africa

SUSU researchers identify biological indicators of long-lasting PTSD

SARS-CoV-2 infection can produce self-attacking autoantibodies

UK emergency aid to help vulnerable countries tackle the Omicron variant

New test-to-stay approach enables kids and staffs to stay in school after COVID exposures

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Orphanhood decreases with the availability of antiretroviral therapy and male circumcision

Once-a-day antiretroviral medicine for children proven to be more effective at suppressing HIV

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