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Regeneron announces EU approval of EYLEA (aflibercept) Injection for retinal vascular disease treatment

Regeneron Pharmaceuticals, Inc. today announced that EYLEA (aflibercept) Injection has been approved by the European Commission for the treatment of visual impairment due to Macular Edema secondary to Retinal Vein Occlusion (RVO).

26 Feb 2015

Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Digital ulcers (DUs) are a frequent, painful, and quality of life altering complication for patients with systemic sclerosis (SSc), a connective tissue disease causing a progressive loss of small blood vessels and resulting changes in organs and tissues. DUs on the fingertips of SSc patients are slow to heal, if they heal at all, as many are unresponsive to any therapies.

26 Feb 2015

Novel technology could improve diagnosis of peripheral arterial disease

Approximately 8 to 12 million people in the United States alone are suffering from peripheral arterial disease (PAD), a common vascular problem that is caused by narrowing of the arteries as a result of plaque buildup. The plaque accumulation leads to an insufficient blood flow to the body's extremities and increases a person's risk for heart attack and stroke by up to six times. PAD is also one of the most serious complications of diabetes.

26 Feb 2015

Researchers find key protein critical to the success of common anti-platelet drug Plavix

Researchers at the UNC School of Medicine have found that the blood platelet protein Rasa3 is critical to the success of the common anti-platelet drug Plavix, which breaks up blood clots during heart attacks and other arterial diseases.

24 Feb 2015

Study results report no benefit from use of sunitinib, sorafenib among patients with kidney cancer

Research results highlighted today at the press conference of a major medical meeting report no benefit from the use of either Sutent (sunitinib) or Nexavar (sorafenib) among patients with locally advanced renal cell carcinoma at high risk of recurrence, the ECOG-ACRIN Cancer Research Group announced.

24 Feb 2015

Johns Hopkins researcher helps discover effectiveness of three drugs for treating patients with DME

A researcher from Johns Hopkins Medicine helped lead colleagues from across the country in a government-sponsored study by the Diabetic Retinopathy Clinical Research Network to discover that three drugs -- Eylea, Avastin and Lucentis -- used to treat diabetic macular edema are all effective. They also discovered that Eylea outperformed the other two drugs when vision loss was moderate to severe.

23 Feb 2015

Researchers reveal new understanding of pathobiology behind vestibular schwannoma

Researchers from the Eaton-Peabody Laboratories of Massachusetts Eye and Ear and the Harvard Medical School/ Massachusetts Institute of Technology Program in Speech and Hearing Bioscience and Technology have revealed new understanding of the pathobiology behind a head and neck tumor that may someday lead to new methods of targeted drug therapy.

21 Feb 2015

New study finds that statins may not reduce risk for Parkinson's disease

The use of statins may not be associated with lowering risk for Parkinson's disease, according to a new study led by researchers at Penn State College of Medicine and National Institute of Environmental Health Sciences. The findings cast doubts on reports suggesting that the cholesterol-lowering medications may protect against this neurodegenerative brain disorder.

20 Feb 2015

Penn State researchers explore hydrogen sulfide's probable role in regulating blood pressure

Widely considered simply a malodorous toxic gas, hydrogen sulfide is now being studied for its probable role in regulating blood pressure, according to researchers.

20 Feb 2015

Clinical study comparing effectiveness of three standard treatments for DME published in NEJM

Regeneron Pharmaceuticals, Inc. today announced that results from the National Institutes of Health-sponsored, Diabetic Retinopathy Clinical Research Network comparative effectiveness study in patients with Diabetic Macular Edema (Protocol T) were published in the New England Journal of Medicine and a corresponding slide set was posted online at DRCR.net.

20 Feb 2015

Targeting pericytes and ANG2 signaling may help treat certain breast cancers

Tumors require blood to emerge and spread. That is why scientists at The University of Texas MD Anderson Cancer Center believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach when combined with vascular growth factors responsible for cell death.

19 Feb 2015

NYU Langone, Technion collaborate to advance cancer research

In a groundbreaking step forward to advance global collaboration in the fight against cancer, two of the world's preeminent academic and research institutions -- NYU Langone Medical Center and the Technion-Israel Institute of Technology -- formally announced a $9 million gift from philanthropists Laura and Isaac Perlmutter that will fund two major, joint research endeavors with potentially far-reaching impact in advancing cancer research.

19 Feb 2015

CryoLife's revenues increase 5% to $37.2M in fourth quarter 2014

CryoLife, Inc., a leading medical device and tissue processing company focused on cardiac and vascular surgery, announced today its results for the fourth quarter and full year of 2014.

17 Feb 2015

Eight clinical researchers selected as finalists for Outstanding Investigator Award at Cardiology 2015

Pediatric cardiology researchers and clinicians from numerous centers from around the world are gathering at the Cardiology 2015: the 18th Annual Update on Pediatric and Congenital Cardiovascular Disease conference, sponsored by The Children's Hospital of Philadelphia and Phoenix Children's Hospital on Feb. 11 to Feb. 15 in Scottsdale, Ariz.

16 Feb 2015

Henry Ford physicians suction cancerous tumor from vein in metastatic kidney cancer patient

Physicians at Henry Ford Hospital successfully suctioned a cancerous tumor from a major vein in a patient with metastatic kidney cancer, clearing the way for him to undergo a minimally-invasive kidney removal. This allowed him to participate in a clinical trial using genetic material from his tumor to produce a vaccine to help fight his metastatic disease.

16 Feb 2015

Vascular News and Research

Regeneron announces EU approval of EYLEA (aflibercept) Injection for retinal vascular disease treatment

Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Novel technology could improve diagnosis of peripheral arterial disease

Researchers find key protein critical to the success of common anti-platelet drug Plavix

Study results report no benefit from use of sunitinib, sorafenib among patients with kidney cancer

Johns Hopkins researcher helps discover effectiveness of three drugs for treating patients with DME

Researchers reveal new understanding of pathobiology behind vestibular schwannoma

New study finds that statins may not reduce risk for Parkinson's disease

Penn State researchers explore hydrogen sulfide's probable role in regulating blood pressure

Clinical study comparing effectiveness of three standard treatments for DME published in NEJM

Targeting pericytes and ANG2 signaling may help treat certain breast cancers

NYU Langone, Technion collaborate to advance cancer research

CryoLife's revenues increase 5% to $37.2M in fourth quarter 2014

Eight clinical researchers selected as finalists for Outstanding Investigator Award at Cardiology 2015

Henry Ford physicians suction cancerous tumor from vein in metastatic kidney cancer patient

Research finding could lead to new therapeutic target for treating hypertension in males

PAH survival unaffected by rheumatoid arthritis origin

Mechanistic subtypes of IPAH revealed

Omega-3 could supplement anti-VEGF treatment in AMD

Choroidal thickness reduced in diabetic macular oedema patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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