Embryonic Development News and Research

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Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.

Research shows key role of diffusion dynamics in stem cell differentiation and tissue development

Gradients of molecular signaling factors play an essential role in numerous events in embryonic development, from patterning limb and organ formation to the intricate shaping of the brain and neuroanatomical architecture.

27 Jul 2017

New report proposes strategy to evaluate low-dose toxicity of endocrine disruptors

A new report by the National Academies of Sciences, Engineering, and Medicine proposes a strategy that the U.S. Environmental Protection Agency should use to evaluate the evidence of adverse human health effects from low doses of exposure to chemicals that can disrupt the endocrine system.

18 Jul 2017

Mutations arising after conception may play vital role in autism

A study of nearly 6,000 families, combining three genetic sequencing technologies, finds that mutations that occur after conception play an important role in autism.

17 Jul 2017

Cellular antennae play key role in muscle-to-fat transformation

Like it or not, as we age, our muscle cells are slowly exchanged, one by one, for fat cells. This process quickens when we injure a muscle, and an extreme form of this process is also seen in muscle-wasting diseases such as Duchenne muscular dystrophy (DMD).

13 Jul 2017

New research offers crucial step towards understanding cause of myopathy

Pioneering research using the tropical zebrafish could provide new insights into the genetic basis of myopathy, a type of human muscle disease.

6 Jul 2017

Study uncovers mechanism underlying nerve cell organization in the spinal cord of developing embryo

Scientists have uncovered how nerve cells in the spinal cord are organized in precise patterns during embryo development - a finding that could give insight into regenerative medicine.

29 Jun 2017

Chicken models may shed light on how humans develop sensitive daytime vision

Humans belong to a select club of species that enjoy crisp color vision in daylight, thanks to a small spot in the center of the retina at the back of the eye.

23 Jun 2017

Human colon organoids fill gap in effectively modeling common GI diseases

Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell.

22 Jun 2017

Study finds link between common household chemicals and birth defects in mice

A new study at the Edward Via College of Osteopathic Medicine and the Virginia-Maryland College of Veterinary Medicine at Virginia Tech has found a connection between common household chemicals and birth defects.

16 Jun 2017

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes.

25 May 2017

KU Leuven researchers identify vital role of TET1 protein in earliest stages of embryonic development

In the earliest stages of embryonic development, a protein known as TET1 may be the factor that tips the balance toward health or disease.

18 May 2017

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet in Munich led by Professor Heiko Hermeking have now uncovered the molecular mechanism that links the two phenomena.

11 May 2017

Improper methylation of cilia protein linked to increased risk of neural tube defects

Research published online in The FASEB Journal shows that the improper methylation of a protein called "Septin2," which regulates the structure of cilia, was associated with an increased risk of having a neural tube defect (NTD) and confirms that cilia are important factors in determining susceptibility of NTDs.

11 May 2017

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Among scientists specializing in the area, the mechanisms behind the signaling function of the Hedgehog (Hh) receptor pathway remain a mystery. Xiaoyen Zheng, Ph.D., assistant professor of anatomy and regenerative biology at the George Washington University School of Medicine and Health Sciences, who recently received a $1.7 million grant from the National Institutes of Health and National Institute of General Medical Sciences, is determined to learn more about the Hh pathway.

4 May 2017

Phagocytosis educates the immune system

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation.

4 May 2017

EPFL researchers discover protein that kick-starts gene expression in nascent embryos

The formation of a human embryo starts with the fertilization of the oocyte by the sperm cell. This yields the zygote, the primordial cell that carries one copy each of the maternal and paternal genomes.

2 May 2017

Study describes new targets for precision treatment of meningiomas

Winner of the Integra Foundation Award, Mark W. Youngblood, presented his research, Clinical and Molecular Features of Genomic Subgroups in Meningioma, during the 2017 American Association of Neurological Surgeons Annual Scientific Meeting.

29 Apr 2017

Gene critical for tumor progression also encourages growth of intestinal stem cells, study shows

A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages the growth of cells that support them, according to results of a study led by Johns Hopkins researchers.

28 Apr 2017

Epigenetic changes detectable at birth linked to risk of obesity

These changes, known as epigenetic modifications, control the activity of our genes without changing the actual DNA sequence. One of the main epigenetic modifications is DNA methylation, which plays a key role in embryonic development and the formation of different cell types, regulating when and where genes are switched on.

26 Apr 2017

UCLA research overturns paradigm about how axons grow during embryonic development

New research by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA overturns a long-standing paradigm about how axons -- thread-like projections that connect cells in the nervous system -- grow during embryonic development.

21 Apr 2017

Embryonic Development News and Research

Further Reading

Research shows key role of diffusion dynamics in stem cell differentiation and tissue development

New report proposes strategy to evaluate low-dose toxicity of endocrine disruptors

Mutations arising after conception may play vital role in autism

Cellular antennae play key role in muscle-to-fat transformation

New research offers crucial step towards understanding cause of myopathy

Study uncovers mechanism underlying nerve cell organization in the spinal cord of developing embryo

Chicken models may shed light on how humans develop sensitive daytime vision

Human colon organoids fill gap in effectively modeling common GI diseases

Study finds link between common household chemicals and birth defects in mice

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

KU Leuven researchers identify vital role of TET1 protein in earliest stages of embryonic development

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

Improper methylation of cilia protein linked to increased risk of neural tube defects

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Phagocytosis educates the immune system

EPFL researchers discover protein that kick-starts gene expression in nascent embryos

Study describes new targets for precision treatment of meningiomas

Gene critical for tumor progression also encourages growth of intestinal stem cells, study shows

Epigenetic changes detectable at birth linked to risk of obesity

UCLA research overturns paradigm about how axons grow during embryonic development

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