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Pharmacological suppression of nonsense mutations effective in treating genetic defects

Genetic mutation can disrupt the way human cells make proteins, which in turn leads to inherited disease. David Bedwell, a professor in the University of Alabama at Birmingham (UAB) Department of Microbiology, says scientists are closer than ever to producing drugs that fix this disrupted-protein pathway and drastically improving treatment of genetic disease.

27 Apr 2010

Scientists now closer to produce drugs to fix disease-causing mutations, spare healthy genes

Inherited diseases such as cystic fibrosis can be caused by genetic "nonsense mutations" that disrupt the way human cells make proteins. David Bedwell, Ph.D., a professor in the University of Alabama at Birmingham Department of Microbiology, says scientists are now closer to producing drugs that will fix this disruption and drastically improve treatment of genetic disease.

27 Apr 2010

Melanin-covered nanoparticles may protect bone marrow from harmful radiation therapy effects: Research

Tiny, melanin-covered nanoparticles may protect bone marrow from the harmful effects of radiation therapy, according to scientists at Albert Einstein College of Medicine of Yeshiva University who successfully tested the strategy in mouse models.

27 Apr 2010

AES CHEMUNEX to distribute SDIX's RapidChek food pathogen detection systems in Europe

Strategic Diagnostics Inc., now doing business as SDIX, a leading provider of biotechnology-based products and services for a broad range of life science, biotechnology, diagnostic, and food safety applications, today announced it has signed a distribution agreement with AES CHEMUNEX.

27 Apr 2010

International Day for Fighting Infection focuses on hospital infection control

Hospital acquired infections are the focus for the 3rd International Day for Fighting Infection, being marked on St. George’s Day, as experts meet to look at the evolution of infection control in hospitals.

22 Apr 2010

Bacterial infections often missed in febrile children in the ER

In a new study researchers reveal that up to one third of children with fever due to bacterial infections do not receive antibiotics in the emergency department and 20% of kids receive antibiotics unnecessarily.

22 Apr 2010

ABRAXANE-bevacizumab combination therapy may exhibit potential in treatment of triple-negative breast cancers

Abraxis BioScience, Inc., a fully integrated biotechnology company, announced study results today that demonstrate a regimen of ABRAXANE® (paclitaxel protein-bound particles for injectable suspension) (albumin-bound) given in combination with bevacizumab (Avastin®) may have potential in the treatment of triple-negative breast cancers.

21 Apr 2010

Kenta Biotech presents positive Phase IIa results of panobacumab

Kenta Biotech has presented positive Phase IIa results of its lead drug candidate, panobacumab (KBPA101), with all patients completing the treatment for hospital-acquired pneumonia and ventilator-acquired pneumonia caused by P. aeruginosa achieving an effective clearance of pneumonia as well as a 100% survival rate.

15 Apr 2010

New findings may aid in developing medications for atherosclerosis and insulin resistance

Scientists from Eastern Virginia Medical School (EVMS) recently presented preliminary research findings that identify a specific gene as a potential new target for treating obesity-related diseases.

15 Apr 2010

NIH awards Corgenix Medical $600,000 grant to develop diagnostic tests for Ebola and Marburg virus

Corgenix Medical Corporation, a worldwide developer and marketer of diagnostic test kits, including innovative products for emerging pathogens and lethal viruses, today announced a major extension of the collaborative effort to combat important viral diseases.

15 Apr 2010

Antibiotic-resistant pneumococci increase rate of bacterial infections in children

In the decade since the introduction of pneumococcal vaccination, significant shifts have occurred in the bacterial strains causing serious pneumococcal infections in children, according to a pair of studies in the April issue of The Pediatric Infectious Disease Journal (www.PIDJ.com). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, and pharmacy.

13 Apr 2010

Rib-X Pharmaceuticals to present delafloxacin Phase 2 study data at 20th ECCMID

Rib-X Pharmaceuticals, Inc., a development-stage antibiotics company with a broad product pipeline based on its innovative discovery platform, today announced that an oral presentation of data for delafloxacin, its lead antibiotic candidate, will be given at the 20th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10-14, in Vienna, Austria by Paul G. Ambrose, Pharm.D, FIDSA, Director, Institute for Clinical Pharmacodynamics, Ordway Research Institute.

12 Apr 2010

Optimer Pharmaceuticals announces results from second Phase 3 clinical study of fidaxomicin

Optimer Pharmaceuticals, Inc. announced that the top-line results from its second fidaxomicin Phase 3 clinical study in patients with Clostridium difficile infection were presented today at the 20th Annual European Congress of Clinical Microbiology and Infectious Diseases in Vienna, Austria.

12 Apr 2010

Researchers investigate effects of nanoparticles on yeast

Nanoparticles are already widely used in everyday products such as cosmetics, textiles, dyes, and paints. It is quite possible that these minute fragments of matter may in future not only come to play a crucial role in medicine and pharmacology, but also in the food and biotechnology industries. The latest research currently being conducted in India has shown that nanoparticles can promote the growth of fungi and even assist plant growth.

12 Apr 2010

Cempra to make poster presentations on CEM-101 and CEM-102 at ECCMID 2010

Cempra Pharmaceuticals today announced poster presentations on its novel antibiotic CEM-101, a next-generation macrolide, and CEM-102, the company's proprietary front-loading oral dosing regimen of sodium fusidate, at the 20th European Congress of Clinical Microbiology and Infectious Disease, April 10 to 13, 2010, in Vienna Austria.

12 Apr 2010

Cempra Pharmaceuticals announces schedule of poster presentations at ECCMID 2010

Cempra Pharmaceuticals today announced its schedule of poster presentations at the 20th European Congress of Clinical Microbiology and Infectious Disease (ECCMID) in Vienna, Austria, on April 10-13, 2010.

8 Apr 2010

Cepheid to launch GeneXpert Infinity-48 in Europe at 20th ECCMID

Cepheid will initiate European launch of its newest addition to the GeneXpert® family of molecular diagnostic testing systems, the GeneXpert Infinity-48, at the 20th annual European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Vienna, Austria. The GeneXpert Infinity-48 System is the world's first and only fully-automated, random-access system designed for management of the entire molecular testing workflow — from sample data, cartridge loading and unloading, to final reporting of test results and disposal of cartridges.

7 Apr 2010

Optimer Pharmaceuticals to present data from fidaxomicin Phase 3 studies at 20th ECCMID

Optimer Pharmaceuticals, Inc. announced that data from the fidaxomicin Phase 3 clinical studies will be presented at the 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) in Vienna, Austria.

7 Apr 2010

BD Diagnostics adds Innova Preanalytical Automated Microbiology Specimen Processor to product portfolio

BD Diagnostics, a segment of BD (Becton, Dickinson and Company), announced today the expansion of its product portfolio with the addition of the BD Innova™ Preanalytical Automated Microbiology Specimen Processor, which is designed to help increase laboratory efficiency and automate the modern microbiology laboratory.

From BD (Becton, Dickinson and Company) 7 Apr 2010

Findings may help devise new strategies for Cryptococcus infections

Highly dangerous Cryptococcus fungi love sugar and will consume it anywhere because it helps them reproduce. In particular, they thrive on a sugar called inositol which is abundant in the human brain and spinal cord.

6 Apr 2010

Microbiology News and Research

Pharmacological suppression of nonsense mutations effective in treating genetic defects

Scientists now closer to produce drugs to fix disease-causing mutations, spare healthy genes

Melanin-covered nanoparticles may protect bone marrow from harmful radiation therapy effects: Research

AES CHEMUNEX to distribute SDIX's RapidChek food pathogen detection systems in Europe

International Day for Fighting Infection focuses on hospital infection control

Bacterial infections often missed in febrile children in the ER

ABRAXANE-bevacizumab combination therapy may exhibit potential in treatment of triple-negative breast cancers

Kenta Biotech presents positive Phase IIa results of panobacumab

New findings may aid in developing medications for atherosclerosis and insulin resistance

NIH awards Corgenix Medical $600,000 grant to develop diagnostic tests for Ebola and Marburg virus

Antibiotic-resistant pneumococci increase rate of bacterial infections in children

Rib-X Pharmaceuticals to present delafloxacin Phase 2 study data at 20th ECCMID

Optimer Pharmaceuticals announces results from second Phase 3 clinical study of fidaxomicin

Researchers investigate effects of nanoparticles on yeast

Cempra to make poster presentations on CEM-101 and CEM-102 at ECCMID 2010

Cempra Pharmaceuticals announces schedule of poster presentations at ECCMID 2010

Cepheid to launch GeneXpert Infinity-48 in Europe at 20th ECCMID

Optimer Pharmaceuticals to present data from fidaxomicin Phase 3 studies at 20th ECCMID

BD Diagnostics adds Innova Preanalytical Automated Microbiology Specimen Processor to product portfolio

Findings may help devise new strategies for Cryptococcus infections

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