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Researchers uncover how dysfunction of brain circuit may contribute to memory loss

Two interconnected brain areas - the hippocampus and the entorhinal cortex - help us to know where we are and to remember it later.

30 Jun 2016

New study may help develop effective medication for severe pain

The nerve cells that transmit pain signals in the body are called nociceptors. When activated they release pro-inflammatory neuropeptides. In order to recognise harmful external influences, nociceptors are equipped with a wide range of receptors.

30 Jun 2016

Study finds better way to evaluate operating skills of orthopaedic residents

In a small study to determine the best way to assess the operating skills of would-be orthopaedic surgeons, Johns Hopkins researchers found that tracking the trainees’ performance on cadavers using step-by-step checklists and measures of general surgical skills works well but should be coupled with an equally rigorous system for tracking errors.

30 Jun 2016

Researchers develop in vitro model system for investigating etiology of NAFLD

Researchers from the Institute for Stem Cell Research and Regenerative Medicine at the University Clinic of Düsseldorf have established an in vitro model system for investigating nonalcoholic fatty liver disease (NAFLD).

30 Jun 2016

Breakthrough research could lead to new drugs to improve heart attack outcomes

A research advance from the Sanford Burnham Prebys Medical Discovery Institute and Stanford University could lead to new drugs that minimize the damage caused by heart attacks.

30 Jun 2016

Fertility awareness apps not smart enough in helping women plan for pregnancy

You might not want to depend on your smartphone app alone to help you avoid or achieve pregnancy, say the authors of a new study. A review of nearly 100 fertility awareness apps finds that most don't employ evidence-based methodology.

30 Jun 2016

Researchers examine effect of GluD2 receptor on parallel fibre regeneration

Nerves in the central nervous system of adult mammals do not usually regenerate when injured. The granule cell, a nerve cell located in the cerebellum, is different.

30 Jun 2016

Researchers develop 2D culture system that mimics development of the whole eye

Research groups led by Professor Kohji Nishida of the Department of Ophthalmology and Endowed Associate Professor Ryuhei Hayashi of the Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, developed a 2D culture system which mimics the development of the whole eye by promoting cell-autonomous differentiation of human iPS cells.

30 Jun 2016

Study highlights continuing problem of MSI in Gulf War veterans

Veterans of the Gulf War are more than twice as likely to have medically unexplained symptoms known as "multisymptom illness" (MSI), compared to Iraq/Afghanistan War veterans, according to an updated research review in the July Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine.

30 Jun 2016

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors.

30 Jun 2016

Scientists develop new nonradioactive method to determine telomere length

UT Southwestern Medical Center cell biologists have identified a new method for determining the length of telomeres, the endcaps of chromosomes, which can influence cancer progression and aging.

30 Jun 2016

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

The Perelman School of Medicine at the University of Pennsylvania has launched a new program, called AAV 3.0, to create new viral vectors to find quicker and better treatments for an array of diseases. James M. Wilson, MD, PhD, a professor of Medicine and director of the Orphan Disease Center, will lead an interdisciplinary team of over 30 scientists to create this new technology platform with support provided by the University of Pennsylvania Health System.

30 Jun 2016

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Viruses must avoid a host's immune system to establish successful infections—and scientists have discovered another tool that viruses use to frustrate host defenses.

30 Jun 2016

Experts compile model list of essential diagnostic tests aiming to improve global health

In a western doctor's office or hospital, patients don't think twice about giving a blood or urine sample that can tell if they have a disease or infection, or show if their medicines are working. The samples get rushed to a testing lab with modern equipment that's held to high quality standards.

30 Jun 2016

New IDSA guidelines focus on diagnosis, treatment of deadly aspergillosis

New therapies are improving care, but early diagnosis remains critical in the effective treatment of invasive, a potentially deadly fungal infection, according to new guidelines released by the Infectious Diseases Society of America and published in the journal Clinical Infectious Diseases.

30 Jun 2016

Acupuncture improves headache-related QoL in TBI patients

A study comparing the effectiveness of usual care alone to usual care plus either auricular or traditional Chinese acupuncture in treating patients with headaches due to a previous traumatic brain injury (TBI) showed a significant improvement in headache-related quality of life (QoL) with the addition of acupuncture.

30 Jun 2016