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First ever analysis of genetic variation between different regions of same tumour

Taking a sample from just one part of a tumour may not give a full picture of its 'genetic landscape', according to a landmark study published in the New England Journal of Medicine.

8 Mar 2012

MRF clinical trial to examine antigen-specific MS therapy

The Myelin Repair Foundation (MRF) announced today that its research might soon lead into a clinical proof-of-concept trial at the Department of Neuroimmunology and Multiple Sclerosis Research (nims), University Hospital Zürich, Switzerland, and the Institute for Neuroimmunology and Clinical Multiple Sclerosis Research (inims) in Hamburg, Germany.

8 Mar 2012

Appendix cancer different from colon cancer

Researchers at Wake Forest Baptist Medical Center have demonstrated that cancer of the appendix is different than colon cancer, a distinction that could lead to more effective treatments for both diseases.

8 Mar 2012

Ten tips to reduce daily intake of sodium

For people who need to cut back on their daily intake of sodium to control blood pressure and lower the risk of stroke, the key may be in home cooking.

8 Mar 2012

Metformin drug appears to prevent growth of atherosclerosis in patients with HIV

Treatment with the common diabetes drug metformin appears to prevent progression of coronary atherosclerosis in patients infected with HIV.

8 Mar 2012

Doctors identify promising new treatment for hypophosphatasia

Doctors at Washington University School of Medicine in St. Louis, working with Shriners Hospital for Children and other institutions, have identified a promising new treatment for a rare and sometimes life-threatening bone disorder that can affect infants and young children.

8 Mar 2012

Women with chronic heart failure survive longer than their male counterparts

Women with chronic heart failure survive longer than their male counterparts, according to a large analysis of studies comprising data on more than 40,000 subjects. The analysis represents the largest assessment of gender and mortality risk in heart failure - and provides evidence which many randomised trials have failed to do because they have been dominated by male patients.

8 Mar 2012

New inexpensive medical sensor may simplify diagnosis of diseases

An inexpensive new medical sensor has the potential to simplify the diagnosis of diseases ranging from life-threatening immune deficiencies to the common cold, according to its inventors at the Stanford University School of Medicine.

8 Mar 2012

New minimally invasive procedure can treat resistant hypertension

A radically different approach to treating high blood pressure - using a minimally invasive procedure- is being evaluated as part of a Pivotal Phase III 90-site national trial that includes The Carl H. and Edyth Lindner Center for Research and Education at The Christ Hospital.

8 Mar 2012

Roundup: Calif. county mum on probe of Medicaid managed care firm; Suit alleges substandard care for Ariz. prisoners

A Ventura County commission is trying to keep secret the details of a state-ordered investigation into the management and claims procedures of a healthcare plan designed to serve the county's neediest residents. Complaints about alleged late payments and poor management prompted the Department of Health Care Services to request that auditors step in and examine the plan's financial condition and claims practices. Gold Coast Health Plan was launched last year to switch an estimated 110,000 Ventura County Medi-Cal beneficiaries into an HMO-style healthcare plan.

8 Mar 2012

Researchers identify key molecular player in mouse model of kidney disease

In findings that may lead to clinical trials of a promising new drug for kidney disease, researchers at Beth Israel Deaconess Medical Center (BIDMC) and their colleagues have identified a key molecular player and shown how a targeted experimental drug can reverse kidney damage in mouse models of diabetes, high blood pressure, genetic kidney disease, and other kidney injuries.

8 Mar 2012

Sosei initiates SO-1105 Phase I trial in oropharyngeal candidiasis

Sosei Group Corporation, the biopharmaceutical company, today announces that its wholly owned Japanese subsidiary, Sosei Co., Ltd., has initiated a Japanese Phase I trial for SO-1105 for the treatment of oropharyngeal candidiasis.

8 Mar 2012

Researchers make significant strides in the study of Intrahepatic Cholangiocarcinoma

Researchers at the University of Rochester Medical Center's James P. Wilmot Cancer Center have made significant strides in the study of a primary cancer of the liver- Intrahepatic Cholangiocarcinoma (IHCC), also called biliary tract cancer.

8 Mar 2012

Researchers validate CatB protease as target for Alzheimer's

Researchers at the University of California, San Diego, the Medical University of South Carolina, the University of Cincinnati, and American Life Science Pharmaceuticals of San Diego have validated the protease cathepsin B (CatB) as a target for improving memory deficits and reducing the pathology of Alzheimer's disease (AD) in an animal model representative of most AD patients.

8 Mar 2012

First Edition: March 7, 2012

Reporting for Kaiser Health News in collaboration with The Washington Post, Susan Jaffe writes: "In the latest effort to enlist seniors in the fight against Medicare fraud, federal officials have overhauled Medicare billing statements to make it easier to find bogus charges without a magnifying glass."

7 Mar 2012

Nuance enters definitive agreement to acquire Transcend

Nuance Communications, Inc. and Transcend Services, Inc. today announced a definitive agreement for Nuance to acquire Transcend, a leading provider of medical transcription and speech editing services, for approximately $300 million, net, in cash.

7 Mar 2012

Study: Patients need greater access to their electronic medical data

Health care organizations need to do more to help patients realize the full benefits of electronic data from emerging health information exchange systems, according to a new study commissioned by Consumers Union that appears in the March 2012 Health Affairs.

7 Mar 2012

ERH wins PRI's 2012 Best Practices in Risk Management and Patient Safety Award

Physicians' Reciprocal Insurers (PRI), the second largest medical malpractice insurer in New York state, today presented Ellenville Regional Hospital with its 2012 Best Practices in Risk Management and Patient Safety Award.

7 Mar 2012

Heroes of Military Medicine award recipients to be honored on May 2, 2012

The Center for Public-Private Partnerships at The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. is pleased to announce the recipients of the 2012 Heroes of Military Medicine awards.

7 Mar 2012

Study identifies mechanism that explains how cancer cells spread to the lymph nodes

Metastasis is responsible for 90% of deaths in patients with cancer. Understanding the mechanisms responsible for this process is one of the top goals of cancer research. The metastatic process involves a series of steps chained where the primary tumour invades surrounding tissues and ends spreading throughout the body. Ones of the first tissues undergoing metastasis are the lymph nodes surrounding the tumour.

7 Mar 2012