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Combining sonoporation with chemotherapy drug may help improve pancreatic cancer treatment

Researchers at Haukeland University Hospital in Bergen, Norway have combined a laboratory ultrasound technique called "sonoporation" with the commercially-available chemotherapy compound Gemcitabine to increase the porosity of pancreatic cells with microbubbles and to help get the drug into cancer cells where it is needed.

26 May 2016

First large-scale proteogenomic study helps pinpoint genes that drive breast cancer

Building on data from The Cancer Genome Atlas project, a multi-institutional team of scientists has completed the first large-scale "proteogenomic" study of breast cancer, linking DNA mutations to protein signaling and helping pinpoint the genes that drive cancer.

26 May 2016

Bone marrow transplantation dose may have lasting effects on HSC behavior

Unlike aspirin, bone marrow doesn't come with a neatly printed label with dosage instructions. However, a new study published in Cell Reports provides clues about how the dose of transplanted bone marrow might affect patients undergoing this risky procedure, frequently used to treat cancer and blood diseases.

26 May 2016

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

A new study from örebro University, published in Science Signaling today, shows that heart medication reduces the build-up of plaque in the brain's blood vessels in mice. The question is if this is true also in humans? If the answer is yes, it might bring scientists a step closer to developing a medicine against Alzheimer's disease.

25 May 2016

Zika virus infection may cause ocular problems in Brazilian infants with microcephaly

Researchers studying babies with a Zika virus-related birth defect say they have found previously unreported eye problems possibly linked to the virus that could result in severe visual impairment.

25 May 2016

Early diagnosis of lung cancer can increase survival rate by 73%

The UK Lung cancer screening trial (UKLS) has been successfully completed and demonstrated that patients with a high risk of developing lung cancer can be identified with early stage disease and have up to a 73% chance of surviving for five years or more. The UKLS trial was conducted by experts in the University of Liverpool.

25 May 2016

Researchers discover how specific gene inhibits bacterial invasion of colonic epithelia

A group of researchers at Osaka University elucidated how a gene named Ly6/Plaur domain containing 8 (Lypd8) inhibits bacterial invasion of colonic epithelia, regulating intestinal inflammation. This achievement may lead to the development of drugs for ulcerative colitis.

25 May 2016

Nutrition, safety tips for grilling season

Cooking meat, including beef, pork, fish, or poultry, with high-temperature methods such as pan frying or grilling directly over an open flame can increase exposure to chemicals that can cause changes in DNA that may increase the risk of cancer, according to the National Cancer Institute.

25 May 2016

WPI receives patent for novel method of reprogramming human skin cells

Cell therapies for a range of serious conditions, including heart attacks, diabetes, and traumatic injuries, will be accelerated by research at Worcester Polytechnic Institute that yielded a newly patented method of converting human skin cells into engines of wound healing and tissue regeneration.

25 May 2016

Combining vitamin A with chemotherapy may offer promise for pancreatic cancer treatment

Around 8,800 people in the UK are diagnosed with pancreatic cancer each year. It is known as the UK's deadliest cancer, with a survival rate of just 3 per cent. Chemotherapy and radiotherapy alone are relatively unsuccessful in treating the disease, and while surgery to remove the tumour offers the best chance of survival, most patients are diagnosed when the cancer has already spread to other organs.

25 May 2016

PET imaging with PiB may help in early diagnosis of Alzheimer's disease

The effort to find ways to detect and diagnose preclinical Alzheimer's disease (AD) has taken a big step forward with the use of positron emission tomography (PET), a "nuclear medicine" for imaging processes in the body, when PET is used with a special 'tracer' that binds to the amyloid plaques in the brain that are a characteristic cause of AD.

25 May 2016

Sylvester researchers test new KTE-C19 therapy for patients with aggressive non-Hodgkin's lymphoma

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are testing a novel cellular immunotherapy approach to treating patients with diffuse large B-cell lymphoma who have failed standard therapy.

25 May 2016

New technique to grow blood vessels could accelerate growth of regenerative medicine

In addition the technique to grow the blood vessels in a 3D scaffold cuts down on the risk of transplant rejection because it uses cells from the patient. It was developed by researchers from the University of Bath's Department of Pharmacy and Pharmacology, working with colleagues at Bristol Heart Institute.

25 May 2016

First clinical trial to study use of Chinese Herbal Medicines in treating RUTIs

Researchers at the University of Southampton are to study the use of Chinese Herbal Medicines in treating recurrent urinary tract infections (RUTIs), in the first clinical trial of its kind in the UK.

25 May 2016

Clinical trials of anti-cancer agent PAC-1 continue to progress with anonymous funding

Clinical trials of the anti-cancer agent PAC-1 are continuing to expand, thanks to a $7 million angel investment from an anonymous contributor who originally invested $4 million to help get the compound this far in the drug-approval pipeline.

25 May 2016

Study finds link between sodium intake and clinical CVD events in CKD patients

In a study appearing in the May 24/31 issue of JAMA, Jiang He, M.D., Ph.D., of the Tulane University School of Public Health and Tropical Medicine, New Orleans, and colleagues evaluated more than 3,500 participants with chronic kidney disease (CKD), examining the association between urinary sodium excretion and clinical cardiovascular disease (CVD) events.

25 May 2016

Discrimination linked to lower vaccination rates among racial/ethnic minorities

Yearly flu shots are strongly recommended for adults with certain chronic illnesses, but patients of racial/ethnic minority groups are less likely to receive them.

25 May 2016

Depressive symptoms may affect fertility of women

Women with severe depressive symptoms have a decreased chance of becoming pregnant, while the use of psychotropic medications does not appear to harm fertility, a study by researchers from the Boston University Schools of Public Health and Medicine shows.

25 May 2016

Diet-based therapy may improve quality of life in IBS patients

A change in diet can improve the lives of those diagnosed with a common, but hard-to-treat gut disorder.

25 May 2016

Marijuana use among teens declines despite widespread legalization

A survey of more than 216,000 adolescents from all 50 states indicates the number of teens with marijuana-related problems is declining. Similarly, the rates of marijuana use by young people are falling despite the fact more U.S. states are legalizing or decriminalizing marijuana use and the number of adults using the drug has increased.

25 May 2016

Medicine News and Research

Combining sonoporation with chemotherapy drug may help improve pancreatic cancer treatment

First large-scale proteogenomic study helps pinpoint genes that drive breast cancer

Bone marrow transplantation dose may have lasting effects on HSC behavior

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

Zika virus infection may cause ocular problems in Brazilian infants with microcephaly

Early diagnosis of lung cancer can increase survival rate by 73%

Researchers discover how specific gene inhibits bacterial invasion of colonic epithelia

Nutrition, safety tips for grilling season

WPI receives patent for novel method of reprogramming human skin cells

Combining vitamin A with chemotherapy may offer promise for pancreatic cancer treatment

PET imaging with PiB may help in early diagnosis of Alzheimer's disease

Sylvester researchers test new KTE-C19 therapy for patients with aggressive non-Hodgkin's lymphoma

New technique to grow blood vessels could accelerate growth of regenerative medicine

First clinical trial to study use of Chinese Herbal Medicines in treating RUTIs

Clinical trials of anti-cancer agent PAC-1 continue to progress with anonymous funding

Study finds link between sodium intake and clinical CVD events in CKD patients

Discrimination linked to lower vaccination rates among racial/ethnic minorities

Depressive symptoms may affect fertility of women

Diet-based therapy may improve quality of life in IBS patients

Marijuana use among teens declines despite widespread legalization

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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