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Antidote-resistant overdose patients may have received synthetic opioid W-18, suspects anesthesiologist

Months ago, ASRA member and anesthesiologist Anita Gupta, MD, suspected overdose patients had received heroin spiked with a synthetic opioid additive because they were not responding to the antidote, naloxone, routinely used by emergency workers.

25 May 2016

Pilot program that includes video decision aids improves end-of-life care in Hawaii

A program encouraging physicians and other providers to discuss with patients their preferences regarding end-of-life care significantly increased the documented incidence of such conversations and the number of patients with late-stage disease who were discharged to hospice.

24 May 2016

Lancet study highlights long-term effect of 1999 nationwide strategy to reduce teenage pregnancy

Rates of teenage pregnancy in England have halved since the implementation of the Government's Teenage Pregnancy Strategy (TPS) in 1999, and the greatest effect is seen in areas of high deprivation and areas that received the most TPS funding, according to research published in The Lancet.

24 May 2016

ANK3 and other genes may play key role in affecting mood, stress and longevity

The visible impacts of depression and stress that can be seen in a person's face -- and contribute to shorter lives -- can also be found in alterations in genetic activity, according to newly published research.

24 May 2016

Existing MCI screening tools result in more than 7% false-negative error rate, study finds

Mild cognitive impairment (MCI) is a slight but noticeable and measurable decline in cognitive abilities, such as remembering names or a list of items. While changes may not be severe enough to disrupt daily life, a clinical diagnosis of MCI indicates an increased risk of eventually developing Alzheimer's disease or another type of dementia.

24 May 2016

Researchers discover new potential treatment target for liver cancer

Researchers at the University of Eastern Finland and Eberhard Karls Universität Tübingen have discovered a new molecular mechanism that can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer.

24 May 2016

Scientists study how viral evolution occurs

Viruses evolve quickly. A small tweak to the genetic makeup of a mostly mild strain of influenza can give rise to the next pandemic. An equally small change to the same strain in a different setting can fade it into obscurity.

24 May 2016

National Cancer Moonshot initiative needs to target proteins that drive cancer

The National Cancer Moonshot initiative needs to move beyond genomics to target the proteins that are driving cancer, according to an Inova Health System and George Mason University collaborative paper published Thursday in the American Association for Cancer Research.

24 May 2016

Chloride switch controls critical step in basement membrane formation

Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body.

24 May 2016

Telephone-based intervention helps reduce menopause-related insomnia, hot flashes

Chatting on the phone with a "sleep coach" and keeping a nightly sleep diary significantly improve sleep quality and reduce insomnia in women through all stages of menopause, according to a new study published today in JAMA Internal Medicine.

24 May 2016

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine revealed that triple-negative breast cancer (TNBC), which has generally been unresponsive to hormone receptor-targeted treatments, can indeed be treated using vitamin D and androgen receptor-targeted therapy.

24 May 2016

Miniature microscope helps neuroscientists identify how the brain links different memories over time

Using a miniature microscope that opens a window into the brain, UCLA neuroscientists have identified in mice how the brain links different memories over time. While aging weakens these connections, the team devised a way for the middle-aged brain to reconnect separate memories.

24 May 2016

Text messaging intervention may help smokers abstain from smoking relative to controls

A new study from The Miriam Hospital's Centers for Behavioral and Preventive Medicine found that smokers who received a text messaging intervention were more likely to abstain from smoking relative to controls. The paper is published in the Journal of Medical Internet Research mHealth and uHealth.

24 May 2016

Study highlights disparities in care for disadvantaged children with traumatic brain injuries

Children who suffer traumatic brain injuries can face a difficult road to recovery, requiring services such as physical therapy and mental health treatment for months or years to get their young lives back on track.

24 May 2016

BUSM researchers uncover genetic, epigenetic alteration overlaps in breast and ovarian cancer

While breast cancer is the most common cause of cancer death in women worldwide, ovarian cancer also is a significant source of mortality as the fifth leading cause of cancer death among women.

24 May 2016

Food-triggered atopic dermatitis in children may lead to life-threatening anaphylaxis risk

Elimination of the food that triggers atopic dermatitis, or eczema, is associated with increased risk of developing immediate reactions to that food, according to the results of a large-scale study recently published in the Journal of Allergy and Clinical Immunology.

24 May 2016

Novel strategy to predict antigenic evolution of circulating influenza viruses

During the 2014-15 flu season, the poor match between the virus used to make the world's vaccine stocks and the circulating seasonal virus yielded a vaccine that was less than 20 percent effective.

24 May 2016

Personalized DXM-loaded leukosomes may help treat inflammation

Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applications for treating diseases characterized by inflammation, such as cancer and cardiovascular diseases.

24 May 2016

Rare mutation may reduce risk of developing arteriosclerosis by 34%

According to new international research, just less than one per cent of the population is naturally protected against developing chronic coronary artery diseases.

24 May 2016

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

An endoscopist's knowledge of a positive Cologuard test improves colonoscopy performance, according to a poster presentation at last week's Digestive Disease Week conference.

24 May 2016

Medicine News and Research

Antidote-resistant overdose patients may have received synthetic opioid W-18, suspects anesthesiologist

Pilot program that includes video decision aids improves end-of-life care in Hawaii

Lancet study highlights long-term effect of 1999 nationwide strategy to reduce teenage pregnancy

ANK3 and other genes may play key role in affecting mood, stress and longevity

Existing MCI screening tools result in more than 7% false-negative error rate, study finds

Researchers discover new potential treatment target for liver cancer

Scientists study how viral evolution occurs

National Cancer Moonshot initiative needs to target proteins that drive cancer

Chloride switch controls critical step in basement membrane formation

Telephone-based intervention helps reduce menopause-related insomnia, hot flashes

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

Miniature microscope helps neuroscientists identify how the brain links different memories over time

Text messaging intervention may help smokers abstain from smoking relative to controls

Study highlights disparities in care for disadvantaged children with traumatic brain injuries

BUSM researchers uncover genetic, epigenetic alteration overlaps in breast and ovarian cancer

Food-triggered atopic dermatitis in children may lead to life-threatening anaphylaxis risk

Novel strategy to predict antigenic evolution of circulating influenza viruses

Personalized DXM-loaded leukosomes may help treat inflammation

Rare mutation may reduce risk of developing arteriosclerosis by 34%

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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