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Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Cancer patients who are ineligible for clinical trials receive immune checkpoint inhibitors (ICI) at greater rates than patients who are trial eligible despite no survival benefit, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

9 Nov 2021

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Leonard Imbula of the Healthy Mind Lab at Washington University School of Medicine in St. Louis holds a bottle of fluvoxamine, a psychiatric drug that has been shown, in a pair of studies conducted on two continents, to be an effective treatment for people sick with COVID-19.

9 Nov 2021

Targeting Shp2 in oncological treatments appears to worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

9 Nov 2021

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.

9 Nov 2021

Scientists discover gene responsible for doubling the risk of respiratory failure from COVID-19

Scientists at Oxford University have identified the gene responsible for doubling the risk of respiratory failure from COVID-19.

9 Nov 2021

Multiplex network offers a systematic approach to study rare, uncharacterized diseases

Rare diseases are usually caused by a single genetic defect. Nevertheless, the search for the cause and the assessment of the effects is highly complex and difficult.

9 Nov 2021

Clinic-based review board helps reduce opioid prescribing

An internal medicine clinic at Oregon Health & Science University has sharply reduced the amount of opioids prescribed though innovative use of a review board comprising a team of health care professionals from various disciplines to ensure patients' needs are being met.

9 Nov 2021

Exercise can alleviate symptoms of anxiety, study shows

Both moderate and strenuous exercise alleviate symptoms of anxiety, even when the disorder is chronic, a study led by researchers at the University of Gothenburg shows.

9 Nov 2021

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

The current analysis indicates that cTfh cells react to the spike antigen following vaccination are associated with anti-S protein neutralizing antibodies.

9 Nov 2021

Binghamton professor receives grant to develop a faster, less painful way to diagnose lung nodules

A biomedical engineering professor at Binghamton University, State University of New York has received a $2.4 million grant to develop a faster, less painful way to diagnose malignant solitary pulmonary nodules (SPNs).

9 Nov 2021

Intersection of multiple social identities may increase suicide risk for lesbian, gay, and bisexual adults

Suicide risk among lesbian, gay, and bisexual adults varies considerably depending on the intersection between sexual identity and other aspects of identity, such as gender, age, and race/ethnicity, according to a study led by researchers at the National Institute of Mental Health (NIMH), part of the National Institutes of Health.

9 Nov 2021

Study reveals the negative perceptions and emotional impact of pregnancy stretch marks

While stretch marks are commonly associated with pregnancy, the permanency of the skin lesions causes pregnant women and pregnant individuals substantial embarrassment that can negatively impact pregnancy and their quality of life, according to a new study.

9 Nov 2021

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

The current study looked at the impact of the virus on the CNS in the Syrian golden hamster, a useful animal model for COVID-19.

9 Nov 2021

COVID-19 drug candidate with wide-ranging antiviral activity

A new study investigated the antiviral activity and mechanism of action of Brilacidin against multiple human coronaviruses.

9 Nov 2021

Invalidation of potential SARS-CoV-2 protease inhibitors

Researchers identified several structurally disparate compounds that can inhibit the viral protease PLpro and determined whether the identified PLpro inhibitors are truly effective and should be further investigated.

9 Nov 2021

Medicare enrollment blitz doesn’t include options to move into Medigap

Medicare's annual open-enrollment season is here and millions of beneficiaries — prompted by a massive advertising campaign and aided by a detailed federal website — will choose a private Medicare Advantage plan.

9 Nov 2021

As overdose deaths soar, DEA-wary pharmacies shy from dispensing addiction medication

When Martin Njoku saw opioid addiction devastate his West Virginia community, he felt compelled to help. This was the place he'd called home for three decades, where he'd raised his two girls and turned his dream of owning a pharmacy into reality.

9 Nov 2021

A Judge takes his mental health struggles public

In 1972, just 18 days after he was selected to run for vice president with Democratic Sen. George McGovern, Thomas Eagleton was forced off the ticket.

9 Nov 2021

CN Bio and iiCON announce COVID-19 research collaboration

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools.

From CN Bio 9 Nov 2021

Research News and Research

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Targeting Shp2 in oncological treatments appears to worsen the disease

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Scientists discover gene responsible for doubling the risk of respiratory failure from COVID-19

Multiplex network offers a systematic approach to study rare, uncharacterized diseases

Clinic-based review board helps reduce opioid prescribing

Exercise can alleviate symptoms of anxiety, study shows

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Binghamton professor receives grant to develop a faster, less painful way to diagnose lung nodules

Intersection of multiple social identities may increase suicide risk for lesbian, gay, and bisexual adults

Study reveals the negative perceptions and emotional impact of pregnancy stretch marks

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

COVID-19 drug candidate with wide-ranging antiviral activity

Invalidation of potential SARS-CoV-2 protease inhibitors

Medicare enrollment blitz doesn’t include options to move into Medigap

As overdose deaths soar, DEA-wary pharmacies shy from dispensing addiction medication

A Judge takes his mental health struggles public

CN Bio and iiCON announce COVID-19 research collaboration

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