Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Researchers find endothelial dysfunction can predict risk of coronary heart disease

A new study from the Libin Cardiovascular Institute at the University of Calgary's Faculty of Medicine is shedding light on an underlying cause of heart disease.

22 Feb 2011

New study: Rapamycin reverses cardiac muscle damage in LEOPARD syndrome mouse model

Congenital heart diseases affect approximately one in 100 patients, making them the most common type of birth defect and the number-one cause of pediatric deaths.

21 Feb 2011

Investigational heart valve implanted in patient through small puncture hole in leg

Physicians at the Methodist DeBakey Heart & Vascular Center in Houston implanted a new investigational heart valve in a patient through a small puncture hole in the leg.

21 Feb 2011

In the Gulf states rates of heart disease are rising with the economy

Rapid improvement in the socio-economic conditions of the Gulf states has been followed by lifestyle changes now contributing to high rates of cardiovascular disease. Professor Hani Najm, President of the Saudi Heart Association whose annual conference begins 21 February 2011, describes risk factor prevalence rates as "extremely high", particularly in the cities of Saudi Arabia.

20 Feb 2011

Research roundup: Racial disparities in hospital readmissions; evaluating home oxygen costs; Medicare funding hurdles

Thirty-Day Readmission Rates For Medicare Beneficiaries By Race And Site of Care - Using national Medicare data on 30-day readmissions after hospitalizations for heart attack, congestive heart failure and pneumonia, the authors report that "black patients had 13% higher odds of all-cause 30-day readmission than white patients.

19 Feb 2011

FDA grants miRagen's MGN-4893 orphan drug designation for treatment of polycythemia vera

miRagen Therapeutics, Inc., a privately-held biopharmaceutical company focused on improving patients' lives by developing innovative microRNA (miRNA)-based therapeutics for cardiovascular and muscle disease, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to the company's compound MGN-4893 for the treatment of polycythemia vera, a myeloproliferative disease characterized by an overabundance of blood cells and platelets in the body.

18 Feb 2011

Acorda reports fourth quarter net revenue of $133.1 million for full year ended December 31, 2010

Acorda Therapeutics, Inc. today announced its financial results for the fourth quarter and full year ended December 31, 2010.

17 Feb 2011

Mutations in gene linked to structure of the heart seen in Ebstein's anomaly patients

Ebstein's anomaly is a rare congenital valvular heart disease. Now, in patients with this disease, researchers of the Academic Medical Center Amsterdam in the Netherlands, the University of Newcastle, UK and the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have identified mutations in a gene which plays an important role in the structure of the heart.

16 Feb 2011

BG Medicine receives US patent for galectin-3 testing to detect heart failure

BG Medicine, a life sciences company focused on the discovery, development, and commercialization of novel diagnostics based on biomarkers, today announced the issuance of U.S. Patent No. 7,888,137, entitled "Method For Identifying a Subject at Risk of Developing Heart Failure by Determining the Level of Galectin-3 or Thrombospondin-2" to the University of Maastricht. BG Medicine has an exclusive license to this issued patent, which pertains to galectin-3 testing for individuals at risk for heart failure.

16 Feb 2011

New study finds racial disparities among elderly Americans in hospital readmissions

Elderly black patients were more likely to be readmitted to the hospital after a prior hospital stay for a heart attack, heart failure, or pneumonia, according to a new study from Harvard School of Public Health researchers.

16 Feb 2011

Racial disparities in readmissions related to both patient race and site of care

Elderly Medicare black patients have a higher 30-day hospital readmission rate for several conditions including congestive heart failure and pneumonia compared to white patients, that is related in part to higher readmission rates among hospitals that disproportionately care for black patients, according to a study in the February 16 issue of JAMA.

16 Feb 2011

Endologix announces initial PEVAR Trial presentation at 2011 iCON annual meeting

Endologix, developer of minimally invasive treatments for aortic disorders, announced today the presentation of the initial clinical results from the PEVAR Trial at the 2011 iCON annual meeting in Scottsdale, Arizona.

16 Feb 2011

ACC releases CardioSmart 'Survival Guides' for five common heart problems

In recognition of American Heart Month, the American College of Cardiology today released CardioSmart "Survival Guides" for five of the most common heart problems: coronary artery disease, heart failure, arrhythmia, hypertension and heart attack.

16 Feb 2011

Sanofi-Aventis, Boehringer, World Heart Federation collaborate to raise awareness about AF

The World Heart Federation, sanofi-aventis and Boehringer Ingelheim have announced their collaboration on the AF AWARE campaign today, to raise awareness of atrial fibrillation (AF) and its links to severe consequences including cardiovascular mortality, stroke and CV hospitalizations.

16 Feb 2011

New Rush clinic brings trained clinicians to care for patients with pulmonary hypertension

Cardiologists and pulmonologists at Rush University Medical Center have teamed up to provide a new and better approach to treating patients with pulmonary hypertension, a disease affecting the heart and lungs. The new Rush Pulmonary Hypertension Clinic brings together a multidisciplinary team of clinicians with specialized training to care for patients with this very complex disease.

16 Feb 2011

BCVI offers multidisciplinary approach to treat patients with atrial fibrillation

More than 2.6 million Americans suffer from atrial fibrillation —an erratic heartbeat. If left untreated, the condition can lead to stroke or heart failure. For three decades, 58 year old David Ryan was one of the millions of Americans suffering from the disease.

16 Feb 2011

Hospital for Special Care announces opening of comprehensive heart failure in-patient unit in Connecticut

Hospital for Special Care (HSC), one of the nation's largest long-term acute-care hospitals, announces the opening of the first comprehensive heart failure in-patient unit in Connecticut, under the direction of board-certified intensivists and cardiologists.

15 Feb 2011

Heavy alcohol intake can lead to increased risk of AF

Atrial Fibrillation is the most common cardiac arrhythmia. Its name comes from the fibrillating of the heart muscles of the atria, instead of a coordinated contraction. The result is an irregular heartbeat, which may occur in episodes lasting from minutes to weeks, or it could occur all the time for years. Atrial fibrillation alone is not in itself generally life-threatening, but it may result in palpitations, fainting, chest pain, or congestive heart failure.

14 Feb 2011

BioTime to merge Glycosan with OrthoCyte

BioTime, Inc., a biotechnology company that develops and markets products in the field of stem cells and regenerative medicine, today announced it has signed a definitive agreement to merge Utah-based Glycosan BioSystems, Inc. (Glycosan) with BioTime's wholly-owned subsidiary, OrthoCyte Corporation. The acquisition is expected to close by March 18, 2011.

14 Feb 2011

The Lancet publishes CHAMPION trial results against heart failure

The CHAMPION clinical trial was published online today in The Lancet. CHAMPION demonstrated a 30% reduction in the primary efficacy endpoint of heart failure hospitalization rates at 6 months, and a 39% reduction in heart failure hospitalization rates at 15 months for heart failure patients whose treatment was guided by pulmonary artery pressures obtained through a miniature, wireless sensor, compared to control patients receiving standard heart failure treatment.

14 Feb 2011

Heart Failure News and Research

Further Reading

Researchers find endothelial dysfunction can predict risk of coronary heart disease

New study: Rapamycin reverses cardiac muscle damage in LEOPARD syndrome mouse model

Investigational heart valve implanted in patient through small puncture hole in leg

In the Gulf states rates of heart disease are rising with the economy

Research roundup: Racial disparities in hospital readmissions; evaluating home oxygen costs; Medicare funding hurdles

FDA grants miRagen's MGN-4893 orphan drug designation for treatment of polycythemia vera

Acorda reports fourth quarter net revenue of $133.1 million for full year ended December 31, 2010

Mutations in gene linked to structure of the heart seen in Ebstein's anomaly patients

BG Medicine receives US patent for galectin-3 testing to detect heart failure

New study finds racial disparities among elderly Americans in hospital readmissions

Racial disparities in readmissions related to both patient race and site of care

Endologix announces initial PEVAR Trial presentation at 2011 iCON annual meeting

ACC releases CardioSmart 'Survival Guides' for five common heart problems

Sanofi-Aventis, Boehringer, World Heart Federation collaborate to raise awareness about AF

New Rush clinic brings trained clinicians to care for patients with pulmonary hypertension

BCVI offers multidisciplinary approach to treat patients with atrial fibrillation

Hospital for Special Care announces opening of comprehensive heart failure in-patient unit in Connecticut

Heavy alcohol intake can lead to increased risk of AF

BioTime to merge Glycosan with OrthoCyte

The Lancet publishes CHAMPION trial results against heart failure

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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