Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Common diabetes treatment may cause bladder cancer

A commonly used diabetes treatment may increase patients’ risk for bladder cancer, show US study findings.

22 Aug 2012

CIRT to determine whether methotrexate can reduce heart attacks, strokes and CVD deaths

An international multi-site trial has launched to determine whether a common anti-inflammatory drug can reduce heart attacks, strokes, and deaths due to cardiovascular disease in people at high risk for them. This study is being supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health.

22 Aug 2012

PhaseBio commences Glymera Phase 2b study in type 2 diabetes

PhaseBio Pharmaceuticals, Inc., a privately held, clinical-stage biotechnology company developing drugs to treat diabetes, metabolic disease and cardiovascular disease, announced today that it has initiated dosing in a multicenter (USA), randomized, placebo and active comparator controlled Phase 2b study that will enroll approximately 600 patients with type 2 diabetes (hemoglobin A1c 7% - 11%) inadequately controlled with diet and exercise, metformin, a sulfonylurea or a combination of metformin/sulfonylurea.

22 Aug 2012

Gene therapy applied to peripheral arterial disease

Hepatocyte growth factor gene therapy could be used to treat patients with severe peripheral arterial disease, suggest results of a phase I clinical trial.

21 Aug 2012

Study finds decline in incidence of heart failure cases in Ontario

The number of new cases of heart failure in Ontario decreased 33% over a decade, suggesting preventive efforts may be working. However, mortality rates remain high for people with the disease, states a study published in CMAJ (Canadian Medical Association Journal).

21 Aug 2012

Hemodialysis foot ulcer risk not confined to diabetes

Hemodialysis patients with and without diabetes are at risk for foot ulceration, say UK researchers who believe preventive resources must be directed towards both patient groups.

20 Aug 2012

Juventas commences treatment in JVS-100 Phase II STOP-HF trial for late stage heart failure

Juventas Therapeutics, a privately-held clinical-stage company developing novel regenerative therapies for treatment of cardiovascular disease, reports treating the first patient in its STOP-HF trial.

20 Aug 2012

Mylan Pharmaceuticals receives FDA approval for pioglitazone tablets to treat type 2 diabetes

The U.S. Food and Drug Administration today approved the first generic version of Actos (pioglitazone hydrochloride) tablets. Along with diet and exercise, pioglitazone is used to improve blood glucose control in adults with type 2 diabetes.

18 Aug 2012

Biopsy required for accurate renal diagnosis in diabetes

People with diabetes and symptoms of nephropathy should undergo renal biopsy before a diagnosis of diabetic nephropathy is assumed, report researchers.

17 Aug 2012

Affordable Care Act: an interview with Val J. Halamandaris, President of the National Association for Home Care & Hospice (NAHC)

The intent of the Affordable Care Act (ACA) is to provide all Americans with medical insurance. Thirty-five million additional people will be covered, in part by government premiums and in part by making it easier for them to buy their own insurance.

17 Aug 2012

Third universal definition of myocardial infarction to be presented at ESC Congress 2012

A new definition of heart attack will be presented at the ESC Congress 2012. The third universal definition of myocardial infarction (MI) clarifies the controversial area of procedural related MI and will be the gold standard for diagnosis and clinical trial endpoints.

17 Aug 2012

UCLA performs first transcatheter aortic valve replacement using new device

UCLA has performed its first transcatheter aortic valve replacement (TAVR), using a new device approved by the U.S. Food and Drug Administration to replace an aortic valve in a patient who was not a candidate for open-heart surgery. The procedure took place August 9th.

16 Aug 2012

Low HDL cholesterol ADVANCEs nephropathy risk in diabetes

People with diabetes are at a greater risk for the development or progression of diabetic nephropathy if they have low levels of high-density lipoprotein cholesterol, report researchers.

15 Aug 2012

Excessive cleanliness may be bad for your health

Research suggests that the antibacterial chemical triclosan, commonly used in personal-care products and antibacterial soaps, may impair the function of cardiac and skeletal muscle.

15 Aug 2012

Roundup: Abortion-rights groups mostly silent on fetal pain laws; Conn. advocates worry over Medicaid cuts; Examining readmission penalties

When new limits on abortions are proposed, abortion-rights groups usually go all out to stop them. So why haven't they gone all out against state fetal-pain laws, enacted in nine states since early 2010? These laws ban abortion after 20 weeks, based on the controversial assertion that the fetus can then experience pain. They're handing victories to anti-abortion groups, and so far there's only one major challenge from an abortion-rights group: in Arizona, where the 9th Circuit Court early this month temporarily blocked the state law.

15 Aug 2012