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Liposuction to manage lymphedema? An interview with Professor John Boyages

Lymphedema is persistent swelling of the arm and/or hand following biopsy or treatment of the axillary lymph nodes for patients with breast cancer. It is due to excess accumulation of protein‐rich fluid in body tissues.

4 May 2016

Controlling cholesterol metabolism could help reduce pancreatic cancer spread

Researchers have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis, pointing to a potential new treatment using drugs previously developed for atherosclerosis.

4 May 2016

Combination of two diagnostic tests can decrease chance of missing tumors by sevenfold

Cytopathology researchers at Houston Methodist Hospital recently found that combining two diagnostic tests, Pap and high-risk human papillomavirus (hrHPV), dramatically decreased the chance of missing tumors and high-grade lesions by sevenfold.

4 May 2016

Researchers develop molecule that binds to GAA enzymes key to progress of Pompe disease

Researchers at Leiden University have made a breakthrough in the study of the hereditary Pompe disease. Together with colleagues in York, they have developed a molecule that binds to the enzyme that is key to the progress of the disease. The findings have been published in ACS Central Science.

4 May 2016

Riluzole drug can reverse key genetic changes linked to Alzheimer's disease

Aging takes its toll on the brain, and the cells of the hippocampus--a brain region with circuitry crucial to learning and memory--are particularly vulnerable to changes that can lead to Alzheimer's disease or cognitive decline. With the hope of counteracting the changes that can lead to these two conditions, researchers at Rockefeller University and their colleagues have begun examining the effects of a drug known to affect this circuitry.

4 May 2016

New HIV infections and transmission rate in the U.S. drop, but fall short of NHAS goals

The number of new HIV infections and the transmission rate in the United States dropped by 11 and 17 percent, respectively, between 2010 and 2015, but fell short of the goals put forth by President Obama's U.S. National HIV/AIDS Strategy (NHAS), researchers from the Perelman School of Medicine at the University of Pennsylvania and Johns Hopkins Bloomberg School of Public Health reported this week in the journal AIDS and Behavior.

4 May 2016

Biomedical researcher wins 2016 Gutenberg Research Award for work on programmed cell death

The Gutenberg Research College of Johannes Gutenberg University Mainz has chosen to give the 2016 Gutenberg Research Award to American biomedical researcher Dr. Vishva Dixit for his groundbreaking work in the field of programmed cell death.

4 May 2016

Important changes in social lives of older adults indicate cognitive decline

Small changes in the social lives of older people are early red flags showing that their thought processes and brain functioning could be on the decline. This is according to Ashwin Kotwal of Brigham and Women's Hospital in the US, who led a study¹ in the Journal of General Internal Medicine, published by Springer.

3 May 2016

Understanding effects of freeze-thawing, intravenous delivery on MSC function

Before the therapeutic potential of using human tissue-derived mesenchymal stromal cells (MSC) to treat immune and degenerative diseases can be fully determined, the effects of freeze-thawing and intravenous delivery on MSC function must be understood.

3 May 2016

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

In a step forward in the push for targeted treatments that can block the specific molecular malfunctions driving cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers have demonstrated how a genetic mutation can drive the most common type of lymphoma as well as melanoma, the deadliest form of skin cancer.

3 May 2016

Study reveals long-term health-related quality of life in bariatric surgery patients

Significant improvement in health-related quality of life was reported by patients 12-14 years after undergoing an uncommon form of bariatric surgery at one U.S. medical center. Follow-up of the 27 patients who underwent biliary pancreatic diversion surgery with duodenal switch (BPD-DS) by the same surgeon is described in an article in Bariatric Surgical Practice and Patient Care, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free for download until June 2, 2016.

3 May 2016

High-intensity exercise, group activity reduce depression among older dementia patients

Both a high-intensity functional exercise programme and a non-exercise group activity, conducted among older care facility residents with dementia, reduced high levels of depressive symptoms. However, exercise had no superior effect on depression, according to a dissertation from Umea University.

3 May 2016

Researchers discover new function of genes in Fanconi anemia pathway

Researchers from UT Southwestern Medical Center have identified an important new function of genes in the Fanconi anemia pathway - a finding that could have implications for development of new therapies to treat this disorder and some cancers.

3 May 2016

Flu vaccinations for pregnant women reduce newborn’s influenza risk during first six months of life

Babies whose moms get flu vaccinations while pregnant have a significantly reduced risk of acquiring influenza during their first six months of life, a new study shows, leading the authors to declare that the need for getting more pregnant women immunized is a public health priority.

3 May 2016

Increased fitness can normalize platelet function quickly

Women with poor physical fitness display significantly higher platelet activation than women with average to very good fitness. That is the major finding of a study of 62 young women, conducted by the research groups of Ivo Volf and Rochus Pokan and sponsored by the Austrian Heart Foundation. Platelet (thrombocyte) activation can lead to the formation of potentially life-threatening blood clots.

3 May 2016

Researchers examine critical role of hypoxia in induction, amplification of FOP lesions

The cellular response to the lack of oxygen fans the flames of flare-ups in a rare bone disorder. In fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, which limits motion, breathing, and swallowing, among a host of progressive symptoms.

3 May 2016

Study shows impact of increasing number of opioid-related hospitalizations on health care costs

Infection is a serious complication of intravenous drug abuse and a major cause of illness and death among intravenous drug users. As the national problem of opioid abuse, including of heroin, continues to grow, new research by clinicians at Beth Israel Deaconess Medical Center and the VA Boston Healthcare System, published today in the May issue of the journal Health Affairs, offers new insights into the significant impact of the trend on opioid-related hospitalizations, infectious complications and health care costs.

3 May 2016

New project explores role of mosquitoes in transmission of pathogens in Austria

In the wake of climate change and globalisation, non-indigenous mosquito species establish in Europe together with the pathogens they transmit. A project funded by the Austrian Science Fund FWF is currently investigating mosquito species found in Austria and their role in the transmission of pathogens.

3 May 2016

Olympus launches new CKX-CCSW cell confluency checker software

Accurate cell confluency measurements are now quick to perform on cell cultures with the Olympus CKX-CCSW confluency checker software. Without having to remove cells from the vessel, the software quantifies the exact growth density to quickly help scientists decide on the next step and optimise cultivation conditions.

From Evident Corporation - Life Sciences 3 May 2016

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia. The results of the multi-center, single arm, phase III study are published in Diabetes Care on Monday, April 18. The research was funded by National Institute of Health grants through the National Institute of Allergy and Infectious Diseases and the National Institute for Diabetes and Digestive and Kidney Disease.

3 May 2016

Medicine News and Research

Liposuction to manage lymphedema? An interview with Professor John Boyages

Controlling cholesterol metabolism could help reduce pancreatic cancer spread

Combination of two diagnostic tests can decrease chance of missing tumors by sevenfold

Researchers develop molecule that binds to GAA enzymes key to progress of Pompe disease

Riluzole drug can reverse key genetic changes linked to Alzheimer's disease

New HIV infections and transmission rate in the U.S. drop, but fall short of NHAS goals

Biomedical researcher wins 2016 Gutenberg Research Award for work on programmed cell death

Important changes in social lives of older adults indicate cognitive decline

Understanding effects of freeze-thawing, intravenous delivery on MSC function

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

Study reveals long-term health-related quality of life in bariatric surgery patients

High-intensity exercise, group activity reduce depression among older dementia patients

Researchers discover new function of genes in Fanconi anemia pathway

Flu vaccinations for pregnant women reduce newborn’s influenza risk during first six months of life

Increased fitness can normalize platelet function quickly

Researchers examine critical role of hypoxia in induction, amplification of FOP lesions

Study shows impact of increasing number of opioid-related hospitalizations on health care costs

New project explores role of mosquitoes in transmission of pathogens in Austria

Olympus launches new CKX-CCSW cell confluency checker software

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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