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Acute liver failure after massive hepatectomy improves with liver cell transplantation

Liver failure often occurs after an extensive hepatectomy, which is the surgical resection of the liver. While liver cell transplantation is a useful therapy for acute liver failure after massive hepatectomy, when cells are transplanted through liver portal veins raises the risk of embolization, such as the formation and movement of a blood clot, often with fatal consequences.

26 Apr 2016

Study reveals how visceral fat contributes to insulin resistance, inflammation

Researchers have long-known that visceral fat - the kind that wraps around the internal organs - is more dangerous than subcutaneous fat that lies just under the skin around the belly, thighs and rear. But how visceral fat contributes to insulin resistance and inflammation has remained unknown.

26 Apr 2016

Innovative strategy can reverse symptoms in neurodegenerative diseases

Alzheimer's and Parkinson's disease are the two most common neurodegenerative disorders worldwide and cause untold suffering to millions of patients and their families. Treatments for these diseases are limited, and no cures exist. Now, a new study describes an innovative strategy that reverses symptoms in these neurodegenerative diseases - at least in fruit flies which had been genetically altered to model the diseases.

26 Apr 2016

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

With a cure rate approaching 90 percent, acute lymphoblastic leukemia (ALL) - the most common type of childhood cancer - is often hailed as one of the "success stories" of modern cancer treatment. But up to 20 percent of patients with a high risk of relapse are not cured. That could change with the results from a clinical trial co-led by investigators from NYU Langone Medical Center, which shows giving high doses of a commonly-used chemotherapy drug increases the survival rate for these patients.

26 Apr 2016

Early maternal support boosts robust brain growth in kids

Children whose mothers were nurturing during the preschool years, as opposed to later in childhood, have more robust growth in brain structures associated with learning, memory and stress response than children with less supportive moms, according to research at Washington University School of Medicine in St. Louis.

26 Apr 2016

Derriford Appearance Scale 24 helps identify quality-of-life issues for breast cancer patients

A new study produced by an interdisciplinary team led by Prof. Antonio Giordano, director of the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University, tracks the development process and efficacy of the Italian translation of the Derriford Appearance Scale 24, an important clinical tool in identifying quality-of-life issues for breast cancer patients, especially concerns regarding body shame, depression, anxiety, overall appearance and appearance identity.

26 Apr 2016

New study explores factors that affect Medicare patient’s adherence to psoriasis biologic therapies

About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

26 Apr 2016

UK charity Action on Hearing Loss funds new project to develop medicines for hearing loss

Today, UK charity Action on Hearing Loss announces a major investment to fund a new project to develop medicines to treat age-related hearing loss and noise-induced hearing loss at BioTrinity 2016 – Europe’s Leading Investment and Biopartnering Conference.

26 Apr 2016

University of Leicester-led study finds way to reverse symptoms of Parkinson’s and Alzheimer’s

A five-year study by an international team led from the University of Leicester has found a way of ‘reversing’ symptoms of neurodegenerative diseases such as Parkinson’s and Alzheimer’s – using fruit flies as test subjects.

26 Apr 2016

New blood treatment technology could reduce malaria risk following blood transfusions

Patients, especially children, who undergo blood transfusions in sub-Saharan Africa are at high risk of transfusion-transmitted malaria. A new trial, published in The Lancet today, suggests that treating donated blood with a new technology that combines UV radiation and vitamin B is safe and could minimise the risk of malaria infection following blood transfusions.

26 Apr 2016

Single season of contact sports can cause measurable brain changes

Repeated impacts to the heads of high school football players cause measurable changes in their brains, even when no concussion occurs, according to research from UT Southwestern Medical Center's Peter O'Donnell Jr. Brain Institute and Wake Forest University School of Medicine.

26 Apr 2016

Same genetic changes responsible for gastrointestinal problems in children with autism

Researchers at Columbia University Medical Center have found evidence in mice that, for some types of autism, gastrointestinal difficulties may originate from the same genetic changes that lead to the behavioral and social characteristics of the condition. The study was published in the Journal of Clinical Investigation.

26 Apr 2016

Criminology theory to combat counterfeit, sub-standard medicines

Around the world, especially in developing nations, counterfeit medicines are a real problem. Until now, in many countries there hasn't been a standard protocol to conduct investigations and pursue prosecution.

26 Apr 2016

New study finds no increase in food-specific IgE levels linked to food allergies

A new study using 5,000 stored blood samples found no increase in the presence of food-specific immunoglobulin E (IgE) — a blood marker associated with food allergy — in children's blood between the 1980s and the 2000s.

26 Apr 2016

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen.

26 Apr 2016

Study shows canine AD shares significant features of human version

Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical estimates also show that approximately 10 percent of dogs have atopic dermatitis.

26 Apr 2016

Transforming MR images into body composition measurements: an interview with Olof Leinhard

Today's medical science utilizes relatively simple anthropometric measures that describe the body, such as body mass index (BMI) and waist circumference. All of these measures are approximations of the body with the intention to characterize what's inside reflecting underlying phenomena that underpin the risk for different diseases.

26 Apr 2016

Study sheds light on mechanism of empty memories in epileptic patients

Between seizures and continually, brain cells in epileptic patients send signals that make "empty memories," perhaps explaining the learning problems faced by up to 40 percent of patients. This is the finding of a study in rats and humans led by researchers at NYU Langone Medical Center and published April 25 in Nature Medicine.

26 Apr 2016

Meta-analysis supports combination therapy for PAH patients

A meta-analysis shows that clinical worsening is significantly less likely in patients with pulmonary arterial hypertension if they are given combination treatment, rather than monotherapy.

25 Apr 2016

New photo-switchable molecule for PDT could help treat rapidly growing tumors

Photoswitchable agents might reduce side effects of a chemotherapy. So far, photodynamic therapies have been dependent on oxygen in the tissue. But hardly any oxygen exists in malignant, rapidly growing tumors.

25 Apr 2016

Medicine News and Research

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Study reveals how visceral fat contributes to insulin resistance, inflammation

Innovative strategy can reverse symptoms in neurodegenerative diseases

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

Early maternal support boosts robust brain growth in kids

Derriford Appearance Scale 24 helps identify quality-of-life issues for breast cancer patients

New study explores factors that affect Medicare patient’s adherence to psoriasis biologic therapies

UK charity Action on Hearing Loss funds new project to develop medicines for hearing loss

University of Leicester-led study finds way to reverse symptoms of Parkinson’s and Alzheimer’s

New blood treatment technology could reduce malaria risk following blood transfusions

Single season of contact sports can cause measurable brain changes

Same genetic changes responsible for gastrointestinal problems in children with autism

Criminology theory to combat counterfeit, sub-standard medicines

New study finds no increase in food-specific IgE levels linked to food allergies

Hydrocortisone drug can also prevent lung damage in premature babies

Study shows canine AD shares significant features of human version

Transforming MR images into body composition measurements: an interview with Olof Leinhard

Study sheds light on mechanism of empty memories in epileptic patients

Meta-analysis supports combination therapy for PAH patients

New photo-switchable molecule for PDT could help treat rapidly growing tumors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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