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Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Antibiotic resistance is one of the most challenging problems in modern medicine. A new study by Erida Gjini and Patricia H. Brito from the Instituto Gulbenkian de Ciência, provides a new mathematical model to evaluate the best treatment protocol to clear an infection, by taking into account the role of the host immune system.

20 Apr 2016

New clinical study to evaluate inexpensive drug to prevent type 1 diabetes

A clinical study evaluating a new hypothesis that an inexpensive drug with a simple treatment regimen can prevent type 1 diabetes will be launched in Dundee tomorrow.

20 Apr 2016

Study shows beneficial effect of hNSC transplantation for TBI

Traumatic brain injury (TBI) is a major cause of mortality and morbidity, often causing lifelong disability for those who survive. Treatment is limited to supportive care, but stem cell therapy has received recent attention as a way to promote recovery for injuries to the central nervous system (CNS). In this study, researchers transplanted human neural stem cells (hNSCs) into the brains of mice modeled with TBI to investigate whether the hosts' immune systems and the stem cells acting in concert would enhance repair.

20 Apr 2016

Immunotherapy drug pembrolizumab shrinks tumors in patients with Merkel cell carcinoma

In a clinical trial of the immunotherapy drug pembrolizumab, half of 25 patients with a rare type of virus-linked skin cancer called Merkel cell carcinoma experienced substantial tumor shrinkage lasting nearly three times as long, on average, than with conventional chemotherapy.

20 Apr 2016

Artificial intelligence in healthcare: an interview with Dr Ehud Reiter

Artificial Intelligence has made huge advances in recent years in many areas, including language processing, vision, and machine learning; we are also seeing the emergence of platforms that integrate different kinds of AI, such as IBM Watson (Arria is a Watson ecosystem partner).

20 Apr 2016

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.

20 Apr 2016

Novel strategy for obesity prevention in young children

A novel approach to preventing overweight/obesity in young children by replacing traditional, individual well-child care with a series of group visits that emphasize nutrition-focused interventions during the first 18 months of life was associated with a significantly reduced obesity rate at 2 years of age.

20 Apr 2016

Family interventions may help reduce children's genetic risks for obesity

Children's genetic risks for obesity may be reduced by interventions that strengthen family communication and help children manage their emotions and feelings of satiety, according to a new review of research on the problem.

20 Apr 2016

Small piece of detoxified E. coli wall makes mice lose natural sweet tooth, study finds

Putting just a tiny piece of the wall of detoxified E. coli into their gut make mice lose their natural sweet tooth, researchers report.

20 Apr 2016

Drexel study provides new insight into future treatment of breathing disorders

Bringing a steady supply of fresh air to the lungs can seem like a simple task, but breathing is a careful orchestration of brain and body.

20 Apr 2016

NObreath®: the essential tool for World Asthma Day

Asthma UK found 120,000 asthma sufferers at risk from wrongly prescribed medication, while NICE found 30% of people with asthma suspected to be misdiagnosed.

From Bedfont® Scientific Ltd 20 Apr 2016

Experts discuss recent controversies related to breast cancer screening recommendations

In 2015, American Cancer Society caused a stir in the oncology community—and among women in general—with the updated recommendation that women of average risk for breast cancer should commence annual mammography at age 45.

19 Apr 2016

New drug combination before surgery may improve outcomes in breast cancer patients

Results from the I-SPY 2 trial show that giving patients with HER2-positive invasive breast cancer a combination of the drugs trastuzumab emtansine (T-DM1) and pertuzumab before surgery was more beneficial than the combination of paclitaxel plus trastuzumab.

19 Apr 2016

Removing immunomodulatory protein improves symptoms of muscular dystrophy in mice

Removing an immunomodulatory protein called osteopontin improves the symptoms of mice with muscular dystrophy by changing the type of macrophages acting on damaged muscle tissue, according to a paper published in The Journal of Cell Biology.

19 Apr 2016

New study links specific psychological, social work factors with sleep problems

A new study found that specific psychological and social work factors were associated with sleep problems both concurrently and two years after exposure, indicating prolonged consequences.

19 Apr 2016

Cyclodextrin offers potential new therapy for cardiovascular disease

An American mother's hunch might result in new treatments for patients who can't tolerate conventional cholesterol-lowering drugs.

19 Apr 2016

Delay in radiation therapy increases chances of DCIS recurrence in women

Delaying radiation therapy too long after surgery significantly increases the risk of recurrent tumors in women treated for very early, or what is referred to as "stage 0," breast cancer, according to new research at Washington University School of Medicine in St. Louis.

19 Apr 2016

New therapy strategy for liver disease shows initial measureable success with norUrso

The new therapy strategy for primary sclerosing cholangitis, a liver disease that at present still cannot be cured with medication, shows initial measureable success with the nor-ursodeoxycholic acid (norUrso).

19 Apr 2016

Newly discovered player in epigenetic regulation closely linked to known cancer promoters

If genes form the body's blueprint, then the layer of epigenetics decides which parts of the plan get built. Unfortunately, many cancers hijack epigenetics to modulate the expression of genes, thus promoting cancer growth and survival.

19 Apr 2016

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Asthma is an enormous public health problem that continues to grow larger, in part because scientists don't fully understand how it is caused. Existing therapies don't cure the disease and often don't even significantly alleviate the symptoms. Now, scientists from the Perelman School of Medicine at the University of Pennsylvania and Rutgers University have identified a biological pathway that potentially explains why current asthma therapies don't work well in many cases—and might be targeted to help those patients.

19 Apr 2016

Medicine News and Research

Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

New clinical study to evaluate inexpensive drug to prevent type 1 diabetes

Study shows beneficial effect of hNSC transplantation for TBI

Immunotherapy drug pembrolizumab shrinks tumors in patients with Merkel cell carcinoma

Artificial intelligence in healthcare: an interview with Dr Ehud Reiter

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

Novel strategy for obesity prevention in young children

Family interventions may help reduce children's genetic risks for obesity

Small piece of detoxified E. coli wall makes mice lose natural sweet tooth, study finds

Drexel study provides new insight into future treatment of breathing disorders

NObreath®: the essential tool for World Asthma Day

Experts discuss recent controversies related to breast cancer screening recommendations

New drug combination before surgery may improve outcomes in breast cancer patients

Removing immunomodulatory protein improves symptoms of muscular dystrophy in mice

New study links specific psychological, social work factors with sleep problems

Cyclodextrin offers potential new therapy for cardiovascular disease

Delay in radiation therapy increases chances of DCIS recurrence in women

New therapy strategy for liver disease shows initial measureable success with norUrso

Newly discovered player in epigenetic regulation closely linked to known cancer promoters

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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