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Study shows women may face decreased kidney damage from ischemia reperfusion injury

After a kidney transplant, women may experience decreased kidney damage from ischemia reperfusion injury compared to men due to the impact of gender-specific hormones, suggests a new preclinical study and an analysis of patient data published online in the Journal of Clinical Investigation from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Apr 2016

Penn researchers report results of CAR therapy trial in brain cancer patients

Immune cells engineered to seek out and attack a type of deadly brain cancer known as glioblastoma (GBM) were found to have an acceptable safety profile and successfully migrate to and infiltrate tumors, researchers from Penn Medicine and Harvard University reported at the AACR Annual Meeting 2016.

19 Apr 2016

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Cancer cells often devise ways to survive even in the presence of toxic chemotherapy. Now, a research team led by investigators at Beth Israel Deaconess Medical Center has found a way to attack a process that tumor cells use to escape the effects of standard cancer drugs. The discovery is published online today in the journal Nature Cell Biology.

19 Apr 2016

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia.

19 Apr 2016

New computer algorithm can better characterize functional context of genomic variations in cancer

Cancer is rarely the result of a single mutation in a single gene. Rather, tumors arise from the complex interplay between any number of mutually exclusive abnormal changes in the genome, the combinations of which can be unique to each individual patient.

19 Apr 2016

UNC scientists develop new optogenetic tool to study function of different proteins

Scientists at the University of North Carolina School of Medicine have developed a way to embed light-responsive switches into proteins so that researchers can use lasers to manipulate protein movement and activity within living cells and animals.

19 Apr 2016

Inhibiting adrenaline receptors reduces breast cancer brain metastases

While we look to invent new medicines to treat cancer, a parallel approach to repurpose existing medicines may be highly effective. Stress, mediated by adrenaline, has been suspected to promote cancer growth and this research study shows that by blocking adrenaline receptors in breast cancers, they are less successful in spreading to and growing in the brain.

19 Apr 2016

Researchers develop new method for identifying DNA mutations in single cancer cell

Researchers at The University of Texas MD Anderson Cancer Center have announced a new method for detecting DNA mutations in a single cancer cell versus current technology that analyzes millions of cells which they believe could have important applications for cancer diagnosis and treatment. The results are published in the April 18 online issue of Nature Methods.

19 Apr 2016

Oxidized mitochondrial nucleoids released from neutrophils may contribute to SLE pathogenesis

Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus (SLE) patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response.

19 Apr 2016

AAN’s updated guideline on botulinum toxin use covers four neurologic disorders

The American Academy of Neurology has updated its 2008 guidelines on the use of botulinum toxin for spasticity, cervical dystonia, blepharospasm and migraine headache, based on recent research.

19 Apr 2016

Griffith launches NNEDPro to help GPs provide effective nutrition advice to patients

With a recent report released from the World Health Organisation on the almost four-fold increase in diabetes, Griffith University is stepping in with the launch of a program to help GPs provide effective nutrition advice to their patients.

19 Apr 2016

Royal Society of Medicine, ITN Productions jointly launch new initiative ‘Doctors of the Future’

In a unique communications partnership, the Royal Society of Medicine and ITN Productions have launched a news and current affairs-style programme.

19 Apr 2016

Researchers successfully use stem cells to promote nerve fibre regeneration after spinal cord injuries

Researchers from Hokkaido University in Japan together with an international team of scientists implanted specialized embryonic stem cells into the severed spinal cords of rats.

19 Apr 2016

MR may detect earliest Alzheimer's brain changes

Levels of the brain metabolite and neuroinflammation marker myo-inositol are elevated in asymptomatic patients with abnormal Alzheimer's disease (AD) biomarkers, say researchers. As repo ...

18 Apr 2016

Small fibre neuropathy defies 'dying-back' nerve process

Neuronal degradation in patients with small fibre neuropathy is not dependent on nerve fibre length, study findings suggest.

18 Apr 2016

Women with epilepsy have likelihood of achieving successful pregnancy just as healthy peers

Women with epilepsy are just as likely to achieve a successful pregnancy as women without the neurological disorder, according to a new study led by research teams at multiple centers, including NYU Langone Medical Center.

18 Apr 2016

Cancer causing genetic condition risk in children lower than previously thought

The odds of children having a genetic condition which causes learning difficulties and tumours have been dramatically cut, thanks to genetic analysis led by The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust

18 Apr 2016

ZIKA virus can be transmitted sexually, confirms Inserm study

A study by researchers from Inserm, the Paris Public Hospitals (Bichat Hospital, AP-HP), Aix-Marseille University, and the National Reference Centre for Arboviruses confirms that the ZIKA virus can be transmitted sexually. Their analyses have shown 100% genetic correlation between the form of the virus present in a man who contracted the virus in Brazil and that of a woman who had never travelled in the epidemic area, but who had sexual relations with him. These results are published in The New England Journal of medicine.

18 Apr 2016

Study shows children with rare eye disease have greatest benefit from gene therapy

Scientists at Oregon Health & Science University's Casey Eye Institute and Baylor College of Medicine's Cullen Eye Institute published findings from a two-year Phase I clinical trial in the journal Ophthalmology, which showed that children had the greatest benefit from gene therapy for treatment of Leber congenital amaurosis (LCA) or severe early childhood onset retinal degeneration (SECORD).

18 Apr 2016

Studies confirm benefit of plasma genotyping to predict treatment outcomes for NSCLC patients

The benefit of plasma genotyping to predict treatment benefit in patients with non-small-cell lung cancer (NSCLC) is confirmed in three studies presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland. Researchers however warned that plasma tests are unlikely to fully replace tissue biopsies.

18 Apr 2016

Medicine News and Research

Study shows women may face decreased kidney damage from ischemia reperfusion injury

Penn researchers report results of CAR therapy trial in brain cancer patients

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

New computer algorithm can better characterize functional context of genomic variations in cancer

UNC scientists develop new optogenetic tool to study function of different proteins

Inhibiting adrenaline receptors reduces breast cancer brain metastases

Researchers develop new method for identifying DNA mutations in single cancer cell

Oxidized mitochondrial nucleoids released from neutrophils may contribute to SLE pathogenesis

AAN’s updated guideline on botulinum toxin use covers four neurologic disorders

Griffith launches NNEDPro to help GPs provide effective nutrition advice to patients

Royal Society of Medicine, ITN Productions jointly launch new initiative ‘Doctors of the Future’

Researchers successfully use stem cells to promote nerve fibre regeneration after spinal cord injuries

MR may detect earliest Alzheimer's brain changes

Small fibre neuropathy defies 'dying-back' nerve process

Women with epilepsy have likelihood of achieving successful pregnancy just as healthy peers

Cancer causing genetic condition risk in children lower than previously thought

ZIKA virus can be transmitted sexually, confirms Inserm study

Study shows children with rare eye disease have greatest benefit from gene therapy

Studies confirm benefit of plasma genotyping to predict treatment outcomes for NSCLC patients

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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