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International panel reclassifies a type of thyroid tumor to reduce cancer overdiagnosis

Led by researchers at the University of Pittsburgh School of Medicine, an international panel of pathologists and clinicians has reclassified a type of thyroid cancer to reflect that it is noninvasive and has a low risk of recurrence. The name change, described today in JAMA Oncology, is expected to reduce the psychological and medical consequences of a cancer diagnosis, potentially affecting thousands of people worldwide.

16 Apr 2016

Scientists identify human protein that weakens immune response to HIV, other viruses

Scientists at the University of North Carolina School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have identified a human (host) protein that weakens the immune response to HIV and other viruses. The findings, published today in Cell Host & Microbe, have important implications for improving HIV antiviral therapies, creating effective viral vaccines, and advance a new approach to treat cancer.

16 Apr 2016

New consensus statement guides student-athletes to respond to sudden cardiac arrest

The Journal of the American College of Cardiology today published a consensus statement that establishes guidance for conducting pre-participation screenings of college athletes and encourages emergency action plans for quickly responding to sudden cardiac arrest.

16 Apr 2016

New oral blood thinners can decrease stroke risk in atrial fibrillation patients without frequent monitoring

A new generation of blood thinners can reduce the risk of stroke in patients with atrial fibrillation, without requiring frequent monitoring and dietary restrictions.

16 Apr 2016

MicroRNAs circulating in blood could lead to first diagnostic test for asthma

People with asthma have telltale molecules circulating in their blood, say researchers at Penn State College of Medicine. The discovery could lead to the first diagnostic blood test for asthma, as well as more targeted treatments for the condition.

16 Apr 2016

Scientists discover underlying mechanisms of nerve damage

Recent research by Sandra Rieger, Ph.D., of the MDI Biological Laboratory identifying the underlying mechanisms of peripheral neuropathy, or nerve damage, has raised the prospect that drug therapies can be developed for the treatment of this condition, which causes pain, numbness and/or tingling in the hands and feet. The research was published March 28 in the Proceedings of the National Academy of Sciences.

16 Apr 2016

Radiation plus chemotherapy improves survival of low-grade brain cancer patients

New clinical-trial findings show that patients with a low-grade form of brain cancer who are treated with radiation plus a combination of chemotherapy drugs have better survival than patients treated with radiation alone.

16 Apr 2016

Mouse model offers insight into molecular, neurological basis of stuttering

Mice that vocalize in a repetitive, halting pattern similar to human stuttering may provide insight into a condition that has perplexed scientists for centuries, according to a new study by researchers at Washington University School of Medicine in St. Louis and the National Institutes of Health.

16 Apr 2016

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

The removal of the enzyme Dnmt1 during oligodendrocyte progenitor cell (OPC) differentiation in the central nervous system resulted in inefficient myelin formation and neurological deterioration, including loss of control of bodily movements, in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal Cell Reports. The results could lead to a new understanding of multiple sclerosis and other myelin disorders in humans.

16 Apr 2016

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

A nationwide study of 2.3 million Israeli adolescents, examined from 1967 through 2010, finds an association between elevated body-mass index in late adolescence, and subsequent cardiovascular mortality in midlife.

16 Apr 2016

Scientists identify key pathway that regulates 'switch' between wakefulness and sleep

Falling asleep and waking up are key transitions in everyone's day. Millions of people have trouble with these transitions - they find it hard to fall asleep or stay asleep at night, and hard to stay awake during the day. Despite decades of research, how these transitions work - the neurobiological mechanics of our circadian rhythm - has remained largely a mystery to brain scientists.

16 Apr 2016

New study links high-volume lung transplant centers with lower costs, readmissions

High-volume lung transplant centers have lower transplantation costs and their patients are less likely to be readmitted within 30 days of leaving the hospital following surgery, according to a new study of more than 3,000 Medicare patients who received lung transplants.

16 Apr 2016

Alzheimer's preclinical staging criteria supported

The Alzheimer's disease preclinical staging criteria proposed by the National Institute on Aging and the Alzheimer's Association appear to be valid over more than a decade of follow-up, say researchers.

15 Apr 2016

Study to test effectiveness of worksite exercise regimen to reduce low back injury risk in firefighters

The University of South Florida and Tampa Fire Rescue have launched a randomized controlled trial to assess the effectiveness of a worksite exercise regimen targeted to reduce the risk of low back injury and disability in firefighters -- a physically demanding occupation particularly prone to back problems that can lead to chronic pain and early retirement.

15 Apr 2016

New research suggests women need to wait until 30 to minimize career income losses

Working women who want to minimize career income losses related to motherhood should wait until they are about 30 years old to have their first children, suggests new research from Washington University in St. Louis.

15 Apr 2016

Johns Hopkins study suggests updated universal screening for hepatitis C virus

A review of blood samples for nearly 5,000 patients seen at The Johns Hopkins Hospital Emergency Department suggests that federal guidelines for hepatitis C virus (HCV) screening may be missing up to a quarter of all cases and argues for updated universal screening.

15 Apr 2016

Expanding insurance coverage for elective single-embryo transfer could result in ideal pregnancy outcomes

Expanding insurance coverage for a type of in vitro fertilization known as elective single-embryo transfer could lead to improved health outcomes and lower health care costs, according to a newly published study that included researchers from the University of Colorado School of Medicine.

15 Apr 2016

NeuroLife device helps paralyzed man to perform complex functional movements

Six years ago, he was paralyzed in a diving accident. Today, he participates in clinical sessions during which he can grasp and swipe a credit card or play a guitar video game with his own fingers and hand. These complex functional movements are driven by his own thoughts and a prototype medical system that are detailed in a study published online today in the journal Nature.

15 Apr 2016

Palovarotene drug may prevent multiple musculoskeletal problems linked with FOP

New research in laboratory animals suggests that the drug palovarotene may prevent multiple skeletal problems caused by a rare but extremely disabling genetic bone disease, and may even be a candidate for use in newborn babies with the condition.

15 Apr 2016

Study examines use of cryoablation to reduce phantom limb pain

J. David Prologo, MD, delivered new findings from an Emory Interventional Radiology and Image Guided Medicine study at the Society of Interventional Radiology's 2016 Annual Scientific Meeting. The study examines the use of cryoablation, or extreme cold, to reduce phantom limb pain (PLP) - a condition that causes individuals to perceive chronic pain in amputated limbs. Emory's study shows interventional radiologists who applied cold blasts to patients suffering from PLP significantly reduced their level of pain.

15 Apr 2016

Medicine News and Research

International panel reclassifies a type of thyroid tumor to reduce cancer overdiagnosis

Scientists identify human protein that weakens immune response to HIV, other viruses

New consensus statement guides student-athletes to respond to sudden cardiac arrest

New oral blood thinners can decrease stroke risk in atrial fibrillation patients without frequent monitoring

MicroRNAs circulating in blood could lead to first diagnostic test for asthma

Scientists discover underlying mechanisms of nerve damage

Radiation plus chemotherapy improves survival of low-grade brain cancer patients

Mouse model offers insight into molecular, neurological basis of stuttering

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

Scientists identify key pathway that regulates 'switch' between wakefulness and sleep

New study links high-volume lung transplant centers with lower costs, readmissions

Alzheimer's preclinical staging criteria supported

Study to test effectiveness of worksite exercise regimen to reduce low back injury risk in firefighters

New research suggests women need to wait until 30 to minimize career income losses

Johns Hopkins study suggests updated universal screening for hepatitis C virus

Expanding insurance coverage for elective single-embryo transfer could result in ideal pregnancy outcomes

NeuroLife device helps paralyzed man to perform complex functional movements

Palovarotene drug may prevent multiple musculoskeletal problems linked with FOP

Study examines use of cryoablation to reduce phantom limb pain

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