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Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

microRNAs (miRs) are small endogenous noncoding RNA molecules (20–23 nucleotides) derived from imperfectly paired hairpin RNA structures naturally encoded in the genome that act specifically as triggering molecules to control translational repression or mRNA degradation.

11 Mar 2016

Effective ways to ensure a long, healthy life

More people may be living to 100 and beyond than ever before, but the real challenge is how to become one of them yourself, and how to care for an aging population.

11 Mar 2016

Salvage radical prostatectomy can improve outcomes in prostate cancer patients

Approximately 14 percent of men will be diagnosed with prostate cancer at some point in their lifetimes, according to the National Institutes of Health. Radiation therapy traditionally has been a primary treatment for the cancer, but one-fourth of men have a recurrence of prostate cancer within five years after the therapy.

11 Mar 2016

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

In a combination of both clinical studies of over 4,000 patients and animal model studies, Cleveland Clinic researchers have demonstrated -- for the first time -- that gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke.

11 Mar 2016

Family-based lifestyle counselling helps increase physical activity levels, improve diet quality in children

A recent Finnish study showed that individualised and family-based lifestyle counselling helps 6-8-year-old children increase their physical activity levels and improve their diet quality during a two-year follow-up. The results of the study conducted at the University of Eastern Finland were recently published in Preventive Medicine.

11 Mar 2016

New study shows that structural changes within the spine alter vibration response

Magnetic resonance image isn't everything. A new University of Alberta study shows that vibrating the spine may reveal more when it comes to treating back pain. Teaming with the University of South Denmark to study the lumbar spine of twins, Greg Kawchuk and his team demonstrate that structural changes within the spine alter its vibration response significantly.

11 Mar 2016

Low bone mass higher in HIV-infected males than in females

Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division of Infectious Diseases at Children's Hospital Los Angeles, studied 11 biomarkers associated with inflammation, bone loss and/or bone formation in about 450 individuals - assessed by sex and HIV status - to try to determine causes of this differential bone loss.

11 Mar 2016

Light therapy lessens depressive symptoms among cancer survivors

Light therapy decreased depressive symptoms and normalized circadian rhythms among cancer survivors, according to new research from the Icahn School of Medicine at Mount Sinai presented today at the American Psychosomatic Society in Denver, CO.

11 Mar 2016

Scientists map biological networks of genes to gain new insights on disease mechanisms

Innovative software tools allowed the scientists to construct accurate "maps" of gene networks for about 400 different human cell and tissue types, ranging from immune cells to brain tissues, whereas previous studies were limited to just one or few tissues.

11 Mar 2016

New RI-MUHC-led study may change the way we think about prescribing statins

Millions of people today take statins to help lower their cholesterol level. Currently statins are prescribed to patients based on their future risk of cardiovascular disease - mainly driven by age - which excludes many individuals who may benefit from them. A new study led by the Research Institute of the McGill University Health Centre in Montreal, with collaborators from the United-States, is changing the way we think about prescribing statins. The research team has developed a new approach to determine which individuals should receive these important medications.

11 Mar 2016

Lengthy periods of sedentary behaviour adversely affect health of bus drivers

Led by researchers at Loughborough University as part of the Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit, the pilot study into bus drivers' sedentary behaviour (prolonged sitting) during and outside working hours is the first of its kind to directly measure periods of inactivity in a sample of drivers using an activPAL3™ accelerometer.

11 Mar 2016

People who burn more calories have larger gray matter volume in key brain areas linked to memory, cognition

Whether they jog, swim, garden or dance, physically active older persons have larger gray matter volume in key brain areas responsible for memory and cognition, according to a new study by researchers at the University of Pittsburgh School of Medicine and UCLA.

11 Mar 2016

Southampton researchers explore ADAM33 gene's association with asthma, airway 'twitchiness'

Researchers at the University of Southampton are to study why some people are more likely to develop asthma.

11 Mar 2016

Mucus may hold key to better cancer treatment

What do cancer cells and a runny nose have in common? The answer is mucus; and researchers at the Stephenson Cancer Center at the University of Oklahoma have shown it may hold the key to making cancer treatment better.

11 Mar 2016

Scientists sort out mechanism of Alzheimer's disease development

A group of the Lomonosov Moscow State University scientists, together with their colleagues from the Institute of Molecular Biology, Russian Academy of Sciences and the King's College London, succeeded in sorting out the mechanism of Alzheimer's disease development and possibly distinguished its key trigger.

11 Mar 2016

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

UNC Lineberger Comprehensive Cancer Center researchers have discovered that a deficiency in a key protein that regulates immune system warning signals could be a new biomarker for colorectal cancer, the second largest cancer killer in the United States. They believe the marker could be used to gauge response to a potential new treatment for the disease.

11 Mar 2016

Single-step, rapid life-saving solution for pneumothorax treatment

Pneumothorax is a medical emergency: the collection of air in the pleural space separating the lung from the chest wall, causing it to collapse and resulting in suffocation. Pneumothorax is caused by chest trauma, and is believed to be responsible for over a third of preventable deaths on the battlefield and in terror attacks.

10 Mar 2016

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Some patients with breast cancer, lung cancer and leukaemia seem to fare poorly after treatment because of the effects of a particular gene, a new study finds.

10 Mar 2016

New procedure allows kidney transplants from incompatible donors

Researchers have found a way to stop patients rejecting kidneys that have come from incompatible donors, potentially slashing the waiting time for thousands of people in desperate need of the procedure.

10 Mar 2016

Popular kidney cancer drugs do not reduce incidence of recurrence

Two widely used targeted therapy drugs approved by the FDA for the treatment of metastatic kidney cancer—sorafenib and sunitinib—are no more effective than a placebo in preventing return of the disease to increase life spans of patients suffering from advanced kidney cancer after surgery, according to a new multi-institutional study in the Lancet led by a researcher at the Abramson Cancer Center (ACC) of the University of Pennsylvania.

10 Mar 2016

Medicine News and Research

Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

Effective ways to ensure a long, healthy life

Salvage radical prostatectomy can improve outcomes in prostate cancer patients

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

Family-based lifestyle counselling helps increase physical activity levels, improve diet quality in children

New study shows that structural changes within the spine alter vibration response

Low bone mass higher in HIV-infected males than in females

Light therapy lessens depressive symptoms among cancer survivors

Scientists map biological networks of genes to gain new insights on disease mechanisms

New RI-MUHC-led study may change the way we think about prescribing statins

Lengthy periods of sedentary behaviour adversely affect health of bus drivers

People who burn more calories have larger gray matter volume in key brain areas linked to memory, cognition

Southampton researchers explore ADAM33 gene's association with asthma, airway 'twitchiness'

Mucus may hold key to better cancer treatment

Scientists sort out mechanism of Alzheimer's disease development

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

Single-step, rapid life-saving solution for pneumothorax treatment

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

New procedure allows kidney transplants from incompatible donors

Popular kidney cancer drugs do not reduce incidence of recurrence

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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