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Roche completes enrollment in Herceptin SC Phase 3 trial for HER2-positive breast cancer

Halozyme Therapeutics, Inc. today announced that Roche has completed patient enrollment for the pivotal Phase 3 study of Herceptin SC (trastuzumab subcutaneous), a subcutaneous formulation that uses Halozyme's Enhanze™ technology (rHuPH20, recombinant human hyaluronidase).

7 Dec 2010

First Edition: December 7, 2010

In today's headlines, Senate leaders appear to be nearing a one-year deal on Medicare's physician pay problem.

7 Dec 2010

Stereotaxis awarded VA Federal Supply Schedule Contract for Niobe Remote Magnetic Navigation System

Stereotaxis, Inc. announced that the United States Department of Veteran Affairs awarded Stereotaxis a Federal Supply Schedule Contract for its Niobe® Remote Magnetic Navigation System, related service agreement, and disposable products. This contract, effective December 15, 2010, is for five years, with a five year renewal option.

7 Dec 2010

Phase 1 study results of Aduro BioTech's CRS-207 presented at AACR Conference on Tumor Immunology

Aduro BioTech, a clinical-stage immunotherapy company, is pleased to announce the presentation of the CRS-207 Phase 1 study at the AACR Special Conference on Tumor Immunology in Miami, Florida by the Principal Investigator, Dr. Dung Le of the Johns Hopkins Kimmel Cancer Center. Dr. Le reported that CRS-207 intravenous administration was well tolerated in subjects with advanced, treatment-refractory cancers. Dr. Le also reported evidence of immune activation and that 6 out of 17 end-stage cancer patients lived 15 months or longer.

7 Dec 2010

Lytix Biopharma, KAEL-GemVax initiate treatment in LTX-315/GV1001 combination anti-cancer vaccine trial

The Norwegian biopharmaceutical company Lytix Biopharma and the Korean biotechnology company KAEL-GemVax announced today the successful first treatment in the study of a combination of LTX-315 and GV1001 as anti-cancer vaccine therapy.

7 Dec 2010

Knee replacement operations cause bacterial infection in the joint

Last year 12 700 knee replacement operations were carried out in Sweden. Most such operations go well, but some patients are affected by bacterial infection in the joint and have to be re-operated. This is a complicated procedure that does not always produce successful results, as shown in a thesis by Anna Stefánsdóttir from Lund University in Sweden.

7 Dec 2010

Adverse birth outcomes partially explain epilepsy mortality

A higher rate of mortality is known to be associated with epilepsy, but the precise contribution of the underlying health factors is unknown. The results from the study of a large cohort of people born in Denmark in 1977 through 2006 were reported today at the American Epilepsy Society meeting here.

7 Dec 2010

Smoking is common among young adults and children with diabetes, raises risk of heart disease

Cigarette smoking is widespread among children and young adults with diabetes yet few health care providers are counseling children and young adults with diabetes to not smoke or stop smoking, according to a new report from the SEARCH Study Group, published online in the Journal of Pediatrics.

7 Dec 2010

New ways to identify patients most likely to respond to cancer vaccine treatment

A personalized vaccine is a powerful therapy to prevent recurrence among certain follicular lymphoma patients, according to the latest results of ongoing research led by the University of Pennsylvania School of Medicine. The new findings show that when these patients - whose tumors are marked by a specific protein that may be present in up to half of people with this type of cancer -- receive a vaccine made from their own tumor cells, disease-free survival is improved by nearly two years, compared with patients who receive a placebo.

7 Dec 2010

Medication and blood transfusion reduce risk of recurrent strokes in young patients with sickle cell anemia

St. Jude Children's Research Hospital investigators discuss results of research into managing iron overload associated with stroke prevention in young sickle cell patients and the search for genetic predictors of stroke risk.

7 Dec 2010

Reason behind recurrence of CLL in lymph nodes and bone marrow after chemotherapy

In research to be presented at the American Society of Hematology (ASH) annual meeting, investigators at Dana-Farber Cancer Institute in Boston offer a new explanation of why chronic lymphocytic leukemia (CLL) tends to recur in the lymph nodes and bone marrow after being cleared from the bloodstream by chemotherapy. Their findings will be reported during in an oral session on Monday, Dec. 6, at 4:45 p.m. in room 315 of the Orange County Convention Center.

7 Dec 2010

Broselow Pediatric Emergency Tape now in electronic format

A well-known paper-based medical chart used by pediatric emergency personnel across America is undergoing a 21st century boost in an collaborative effort between Virginia Tech's College of Engineering, Roanoke-based Carilion Clinic Children's Hospital, and the physician who created the original method some 25 years ago.

7 Dec 2010

People suffering psychotic disorders 12 times more likely to commit suicide

People with psychotic disorders, such as schizophrenia or bipolar disorder, are 12 times more likely to commit suicide than average, according to research released today by King's Health Partners.

7 Dec 2010

Boston Scientific's Close the Gap campaign to raise awareness of heart disease risk factors

Boston Scientific today announced that its Close the Gap campaign is partnering with the Black Coaches and Administrators and college basketball's "The Showcase" to raise awareness of heart disease risk factors for women and minorities.

7 Dec 2010

Clinical trial results of ACY-1215 in multiple myeloma published in scientific journal of ASH

Acetylon Pharmaceuticals today announced the publication of favorable results of preclinical safety and efficacy testing of its oral selective HDAC6 inhibitor drug candidate, ACY-1215, in multiple myeloma.

7 Dec 2010

NanoString secures exclusive worldwide license to develop products for breast cancer intrinsic subtyping

NanoString Technologies, Inc., a privately held life sciences company marketing a complete solution for detecting and counting large sets of target molecules in biological samples, today announced it has secured an exclusive worldwide license from Bioclassifier, LLC to develop in vitro diagnostic and research products for breast cancer intrinsic subtyping.

From NanoString Technologies 7 Dec 2010

Research team creates digital version of Broselow tape for children

7 Dec 2010

Secondhand smoke in the home may cause ear infections in children: Study

Family members who smoke are more apt to feel it is OK to smoke indoors as their children get older. But in households with secondhand smoke, children between 12 and 17 are 1.67 times more prone to have recurrent ear infections compared to adolescents who live in a smoke-free environment, a large new study reveals.

7 Dec 2010

Quantros to demonstrate new patient safety improvement solutions at IHI National Forum

Quantros, a leading provider of clinically-focused data management and decision support solutions for the healthcare industry, will demonstrate several new patient safety improvement solutions at the 22nd Annual Institute for Healthcare Improvement National Forum on Quality Improvement in Health Care, Dec. 5 to 8 in Orlando, FL.

7 Dec 2010

Report: Baltimore cardiologist inserted 'medically unnecessary' stents

Abbott Laboratories, a $30 billion-a-year, Chicago-based pharmaceutical firm, ranked [Dr. Mark] Midei among its top-volume doctors in the Northeast and made plying him with research money and 'VIP trips' part of its business plan in late 2008 — about the time Midei's usage of Abbott-brand stents soared, the report said.

7 Dec 2010

Hospital News and Research

Roche completes enrollment in Herceptin SC Phase 3 trial for HER2-positive breast cancer

First Edition: December 7, 2010

Stereotaxis awarded VA Federal Supply Schedule Contract for Niobe Remote Magnetic Navigation System

Phase 1 study results of Aduro BioTech's CRS-207 presented at AACR Conference on Tumor Immunology

Lytix Biopharma, KAEL-GemVax initiate treatment in LTX-315/GV1001 combination anti-cancer vaccine trial

Knee replacement operations cause bacterial infection in the joint

Adverse birth outcomes partially explain epilepsy mortality

Smoking is common among young adults and children with diabetes, raises risk of heart disease

New ways to identify patients most likely to respond to cancer vaccine treatment

Medication and blood transfusion reduce risk of recurrent strokes in young patients with sickle cell anemia

Reason behind recurrence of CLL in lymph nodes and bone marrow after chemotherapy

Broselow Pediatric Emergency Tape now in electronic format

People suffering psychotic disorders 12 times more likely to commit suicide

Boston Scientific's Close the Gap campaign to raise awareness of heart disease risk factors

Clinical trial results of ACY-1215 in multiple myeloma published in scientific journal of ASH

NanoString secures exclusive worldwide license to develop products for breast cancer intrinsic subtyping

Research team creates digital version of Broselow tape for children

Secondhand smoke in the home may cause ear infections in children: Study

Quantros to demonstrate new patient safety improvement solutions at IHI National Forum

Report: Baltimore cardiologist inserted 'medically unnecessary' stents

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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