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No evidence of toxicity in hemophilia B patients enrolled in gene therapy trial

Investigators report no evidence of toxicity in the four hemophilia B patients enrolled to date in a gene therapy trial using a vector under development at St. Jude Children's Research Hospital and UCL (University College London) to correct the inherited bleeding disorder.

7 Dec 2010

Screening for CCDC40 gene mutations may help determine risk for congenital heart defects

A gene that can cause congenital heart defects has been identified by a team of scientists, including a group from Princeton University. The discovery could lead to new treatments for those affected by the conditions brought on by the birth defect.

7 Dec 2010

Today's Op-Eds: ObamaCare and FEHBP; California prisons; and workhorse Medicaid

Even Washington's stupidest scandals can be revealing, and so it is with the liberal cri de snore that Republicans ought to renounce health insurance. Democrats have inadvertently drawn up another indictment of ObamaCare (12/4).

6 Dec 2010

NovaBay Pharmaceuticals, Galderma expand their multi-year collaboration agreement

NovaBay Pharmaceuticals, Inc., a clinical stage biotechnology company developing first-in-class, anti-infective compounds for the treatment and prevention of antibiotic-resistant infections, and Galderma, a global leading pharmaceutical company dedicated exclusively to the field of dermatology, announce the expansion of their multi-year collaboration agreement. Based on positive data assessing the activity of NovaBay's Aganocide compounds against impetigo, Galderma has agreed to exercise its option for this indication.

6 Dec 2010

ConvaTec Healthcare offers $1,870,000,000 in Senior Secured Notes, Senior Notes

ConvaTec Healthcare, a world-leading developer, manufacturer and marketer of innovative medical technologies for community and hospital care, today announced that in connection with a refinancing of its debt under its existing senior secured and mezzanine facilities and in combination with new senior secured credit facilities, it is offering $1,870,000,000 (equivalent) in Senior Secured Notes and Senior Notes.

6 Dec 2010

Elsevier announces title change for Cancer Genetics and Cytogenetics journal

Elsevier, the world's leading publisher of scientific, technical and medical information, announced today that its highly respected Cancer Genetics and Cytogenetics journal is changing its title to Cancer Genetics and has named Dr. Jaclyn A. Biegel as editor-in-chief.

6 Dec 2010

MBH receives prestigious 2010 Healthcare IT Summit Innovation Award

Autonomy Corporation plc, a global leader in infrastructure software for the enterprise, today announced that Autonomy Meaning Based Healthcare received the prestigious 2010 Healthcare IT Summit Innovation Award for "Solution With Greatest Market Potential." Autonomy was selected for this award by attendees at the 2010 Healthcare IT Summit, including leading healthcare delivery organizations and insurance providers such as Massachusetts General Hospital, University of Pennsylvania Health System, Johns Hopkins Healthcare, UnitedHealth Group, and CIGNA.

6 Dec 2010

Genentech announces Phase II study results of RG1678 for treatment of schizophrenia

Genentech, Inc., a member of the Roche Group, today announced eight-week results from a Phase II study of RG1678, its investigational first-in-class glycine reuptake inhibitor for the treatment of schizophrenia.

6 Dec 2010

New research focusing on VTE presented at ASH Annual Meeting

The latest advances in the treatment of bleeding and clotting disorders will be presented today at the 52nd Annual Meeting of the American Society of Hematology, focusing on venous thrombeombolism, a potentially life-threatening disorder in which abnormal blood clots form in the veins and restrict the flow of blood. New studies examine risk-prediction models and cutting-edge treatment options for patients with VTE.

6 Dec 2010

Preclinical study results for Syk, JAK inhibitor program presented at ASH 2010

Portola Pharmaceuticals, Inc. today announced the presentation of preclinical study results for its novel Syk and JAK inhibitor program at the American Society of Hematology's 52nd Annual Meeting and Exposition. Portola's novel Syk and JAK inhibitors are in development to treat chronic inflammatory diseases, including rheumatoid arthritis, and certain cancers, including non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

6 Dec 2010

Incidence of EPTS in children with TBI more than twice the rate in adults: Study

In the first study to utilize continuous EEG monitoring to define the incidence of early post traumatic seizures in children compared to published rates in adults, investigators at the University of Colorado followed pediatric patients with moderate to severe traumatic brain injury admitted to Denver Children's Hospital over a nine month period.

6 Dec 2010

Amgen announces final study results of Nplate in adults with chronic ITP

Amgen Inc. today announced the final results from a 5-year open-label extension study investigating the long-term efficacy and safety of Nplate (romiplostim) in adult chronic immune (idiopathic) thrombocytopenic purpura. Chronic ITP is a serious autoimmune disorder characterized by low platelet counts in the blood (thrombocytopenia), which can lead to serious bleeding events.

6 Dec 2010

Research highlighting treatment for pediatric SCD, malaria presented at ASH 2010

Red blood cells have the very important role of carrying oxygen from the lungs to the rest of the body; therefore, disorders that affect RBCs can have a significant impact on quality of life. Sickle cell disease and malaria are two common RBC diseases that affect a significant portion of the U.S. and global populations. Sickle cell disease, a genetic blood disorder that causes deformed and dysfunctional red blood cells, affects an estimated 70,000 to 100,000 Americans, while malaria affects approximately 1,500 Americans annually and 190 to 311 million people worldwide.

6 Dec 2010

Cell Therapeutics announces new pixantrone EOS follow up results

Cell Therapeutics, Inc. today announced new pixantrone end of study follow up results from the Company's pivotal phase III PIX301 trial, which results form the basis for the Company's recent Marketing Authorization Application currently under review by the European Medicines Agency.

6 Dec 2010

Immunomedics reports results of milatuzumab-based combination treatments for NHL patients

Immunomedics, Inc., a biopharmaceutical company primarily focused on the development of monoclonal antibody-based products for the targeted treatment of cancer, autoimmune and other serious diseases, today reported that combination treatment with milatuzumab, the first humanized anti-CD74 antibody in clinical testing, and veltuzumab, a second-generation humanized anti-CD20 antibody, resulted in therapeutic responses in heavily pretreated and rituximab-refractory non-Hodgkin's lymphoma patients.

6 Dec 2010

Cyclacel reports preclinical data of CYC065 for treatment of cancer, other serious diseases

Cyclacel Pharmaceuticals, Inc., a biopharmaceutical company developing oral therapies that target the various phases of cell cycle control for the treatment of cancer and other serious diseases, announced today the presentation of new preclinical data for CYC065, a novel, orally-available, cell cycle kinase inhibitor. The data were reported at a poster presentation at the 52nd Annual Meeting of the American Society of Hematology in Orlando, Florida.

6 Dec 2010

ACAAI allergist experts available to comment on new food allergy guidelines

Food allergy experts from the American College of Allergy, Asthma and Immunology are available to comment as the National Institute of Allergy and Infectious Diseases releases the Guidelines for the Diagnosis and Management of Food Allergy on December 6. The ACAAI was one of more than 30 professional organizations, federal agencies and lay organizations who collaborated on the development of these recommendations.

6 Dec 2010

Study compares efficacy of two treatments for iron overload caused by chronic transfusion therapy

Monthly blood transfusions combined with daily medication to remove the resulting excess iron remains the best approach for reducing the risk of recurrent strokes in young patients with sickle cell anemia, according to a preliminary analysis of a multicenter trial that includes St. Jude Children's Research Hospital.

6 Dec 2010

Oral levetiracetam may be effective in stopping neonatal seizures

Seizures that occur in the first few weeks of life are a major predictor of future adverse neurological outcomes. Currently approved antiepileptic drugs (AEDs) are effective in stopping seizures in less than 50% of these neonatal cases. The approved therapies can also have undesirable side effects.

6 Dec 2010

Research reveals new standard treatment options for various forms of lymphoma

The next generation of drug therapies and enhanced treatment approaches for various forms of lymphoma are evolving as researchers continue to better understand how these cancers progress. Research will be presented today at the 52nd Annual Meeting of the American Society of Hematology introducing promising new options for the standard treatment of advanced asymptomatic follicular lymphoma, mantle cell lymphoma, and early, unfavorable (referring to patients with clinical stage I or II disease and one or more risk factors) Hodgkin disease.

6 Dec 2010

Hospital News and Research

No evidence of toxicity in hemophilia B patients enrolled in gene therapy trial

Screening for CCDC40 gene mutations may help determine risk for congenital heart defects

Today's Op-Eds: ObamaCare and FEHBP; California prisons; and workhorse Medicaid

NovaBay Pharmaceuticals, Galderma expand their multi-year collaboration agreement

ConvaTec Healthcare offers $1,870,000,000 in Senior Secured Notes, Senior Notes

Elsevier announces title change for Cancer Genetics and Cytogenetics journal

MBH receives prestigious 2010 Healthcare IT Summit Innovation Award

Genentech announces Phase II study results of RG1678 for treatment of schizophrenia

New research focusing on VTE presented at ASH Annual Meeting

Preclinical study results for Syk, JAK inhibitor program presented at ASH 2010

Incidence of EPTS in children with TBI more than twice the rate in adults: Study

Amgen announces final study results of Nplate in adults with chronic ITP

Research highlighting treatment for pediatric SCD, malaria presented at ASH 2010

Cell Therapeutics announces new pixantrone EOS follow up results

Immunomedics reports results of milatuzumab-based combination treatments for NHL patients

Cyclacel reports preclinical data of CYC065 for treatment of cancer, other serious diseases

ACAAI allergist experts available to comment on new food allergy guidelines

Study compares efficacy of two treatments for iron overload caused by chronic transfusion therapy

Oral levetiracetam may be effective in stopping neonatal seizures

Research reveals new standard treatment options for various forms of lymphoma

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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