Knee Replacement News and Research

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Women less satisfied with pain control after TKR surgery

Increased pain following surgery has long been linked to anxiety and "catastrophizing," an extreme response to stress. In a new study presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), 97 patients - men and women - who were about to undergo minimally invasive total knee replacement (TKR) surgery, completed a brief survey to quantify their level of anxiety, as well as their typical level of anxiety and potential for catastrophizing. Pain data was then collected for seven days following surgery.

9 Feb 2012

Telephone support can improve outcomes in high-risk TKR patients

Poor emotional health and morbid obesity are associated with less functional gain following total knee replacement (TKR) surgery. In the new study, "Can Telephone Support During Post-TKR Rehabilitation Improve Post-op Function: A Randomized Controlled Trial," presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), approximately 180 patients were categorized by gender, body mass index (BMI) and emotional health.

8 Feb 2012

Study highlights benefits of TKR in elderly patients with osteoarthritis

New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) highlights the benefits of total knee replacement (TKR) in elderly patients with osteoarthritis, including a lower probability of heart failure and mortality.

7 Feb 2012

Anticoagulation drugs can prevent PE, DVT after total joint replacement

Following a total joint replacement, anticoagulation (blood thinning) drugs can prevent Deep Vein Thrombosis (DVT), a blood clot deep within the extremities, or a pulmonary embolism (PE), a complication that causes a blood clot to move to the lungs.

7 Feb 2012

AJRR selects Remedy Informatics to build national hip and knee replacement registry

The American Joint Replacement Registry (AJRR) has selected Remedy Informatics, the leading provider of registries for Life Science, to build a registry to collect data on all primary and revision total joint replacement procedures in the United States. Representatives from AJRR and Remedy Informatics will unveil the new registry at the American Association of Orthopaedic Surgeons (AAOS) Annual Meeting in San Francisco, Feb. 7 – Feb. 11.

7 Feb 2012

ConforMIS adds 22 patents to patient-specific implants and instrumentation systems portfolio

ConforMIS, Inc. today announced it has completed its most productive period to date in the development of its intellectual property with the addition of 22 issued patents to its portfolio since January 2011.

6 Feb 2012

ConforMIS raises $89M in Series E round of funding

Surpassing all previous fundraising rounds, privately-held medical device company ConforMIS, Inc. announced today that it has raised $89 million in a Series E round of funding, with additional funds beyond this amount committed upon meeting certain milestones.

30 Jan 2012

Incidence of knee arthroplasty higher in women, finds study

Researchers in Finland found that annual cumulative incidences of partial and total knee arthroplasty, commonly known as knee replacement surgery, rose rapidly over a 27-year period among 30 to 59 year-olds in that country, with the greatest increase occurring in patients aged 50 to 59 years.

17 Jan 2012

Vejthani Hospital Bangkok offers High Tibial Osteotomy Surgery for osteoarthritis

Vejthani Hospital Bangkok offers a High Tibial Osteotomy Surgery for osteoarthritis at TJR Center. The procedure prolongs the life of a damaged knee, helps relieve pain in the knee and delays the need for a total knee replacement.

28 Dec 2011

Enrollment complete in ThromboGenics, BioInvent TB-402 Phase IIb trial on VTE

ThromboGenics NV and co-development partner BioInvent International announce today that they have completed the enrolment of a 632-patient Phase IIb trial with their novel long-acting anticoagulant TB-402 for the prophylaxis of venous thromboembolism (VTE) after total hip surgery. The trial has recruited patients from 36 centers across Europe.

17 Dec 2011

Patients need less blood after surgery than is widely thought

Patients need less blood after surgery than is widely thought. A new study comparing two plans for giving blood transfusions following surgery showed no ill effects from postponing transfusion until patients develop signs of anemia or their hemoglobin concentration falls below 8 g/dL.

16 Dec 2011

New knee replacement model increases likelihood of early revision surgery

Orthopaedic surgeons face a steep learning curve to get used to new prostheses, and the instruments and methods that go with them, before new total knee replacement procedures are as safe and effective as conventional methods. Patients who undergo the first 15 operations using a new device in a hospital are 48 percent more likely to need early revision surgery, than patients undergoing an operation to fit a prosthesis previously used in the hospital.

15 Dec 2011

ISIS-FXIRx reduces Factor XI activity without bleeding in healthy volunteers

Isis Pharmaceuticals, Inc. announced today positive results from a Phase 1 study with ISIS-FXIRx. The results demonstrated that treatment with ISIS-FXIRx produced dose-dependent statistically significant reductions of up to 78 percent in Factor XI activity.

13 Dec 2011

Factors associated with increased risk of in-hospital falls after total hip or knee replacement surgery

Investigators from Hospital for Special Surgery have identified factors that are associated with an increased risk of in-hospital falls after total hip or knee replacement surgery.

5 Dec 2011

Vejthani Hospital offers Computer Assisted Replacement Surgery on knee arthroplasty

Vejthani Hospital Bangkok offers Computer Assisted Replacement Surgery on knee arthroplasty, the intelligent medical surgery software at TJR Center of Vejthani Hospital.

3 Dec 2011

Xarelto (rivaroxaban) shows success as blood thinner in acute coronary syndrome

A new anti-blood clotting drug – Xarelto (rivaroxaban) has shown clinical success. It may help people with “acute coronary syndrome” lower their risk of death, subsequent heart attack or stroke, a new study finds. Acute coronary syndrome is term that includes people with angina or prior history of heart attack.

15 Nov 2011

Stem cell bandage human clinical trial for torn meniscal cartilage

The company behind a pioneering stem cell bandage, believed to be the world's first adult and autologous (patient's own) stem cell treatment designed to heal torn meniscal cartilage, can now take the technology to human clinical trials thanks to an investment from one of the UK's most successful entrepreneurs.

14 Nov 2011

Opioid-dependent patients have worse outcomes before knee replacement surgery

Patients who are dependent on opioids (narcotic pain relievers) for pain management before knee replacement surgery have much more difficulty recovering, a study recently published in the Journal of Bone and Joint Surgery (JBJS) has found.

13 Nov 2011

Sports participation may increase risk of knee osteoarthritis

According to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago, participating in certain sports such as soccer, as well as elite long distance running, weight lighting and wrestling may increase the risk of developing knee osteoarthritis.

7 Nov 2011

Nearly 6.5M younger Americans to be diagnosed with knee OA in next ten years

Based on current trends, nearly 6.5 million Americans between the ages of 35 and 84 are expected to be diagnosed with knee osteoarthritis in the next 10 years, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago.

7 Nov 2011