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Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Within the brain and other parts of the nervous system, synapses are key junctional points in between neurons (the nerve cells) where critical signals are transmitted. More specifically, the "glutamatergic" synapses are the prime "excitatory" synapse junctions that neurons use to activate each other and are known to have broad diversity in size and shape.

7 Oct 2021

Massage can enhance healing and strength of muscles, study finds

Massage has been used to treat sore, injured muscles for more than 3,000 years, and today many athletes swear by massage guns to rehabilitate their bodies. But other than making people feel good, do these "mechanotherapies" actually improve healing after a severe injury? According to a new study from researchers at Harvard's Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineering and Applied Sciences (SEAS), the answer is "yes."

7 Oct 2021

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues. The findings appeared on Oct. 6, 2021, in Science Advances.

7 Oct 2021

Protecting the ozone layer could prevent cancer cases and other diseases in the U.S

An international agreement to protect the ozone layer is expected to prevent 443 million cases of skin cancer and 63 million cataract cases for people born in the United States through the end of this century, according to new research.

7 Oct 2021

Teaching magic tricks to kids with ADHD can enhance their feelings of self-esteem and confidence

Teaching magic tricks to children with disabilities can enhance their feelings of self-esteem and confidence, a study has shown.

7 Oct 2021

Mouse brain atlas may help understand the complex circuits of the human brain

The circuits of the human brain contain more than 100 billion neurons, each linked to many other neurons via thousands of synaptic connections, resulting in a three-pound organ that is profoundly more complex than the sum of its innumerable parts.

7 Oct 2021

Study illuminates how BRD4 protein directs the spatial organization of DNA within cell nucleus

New research is advancing understanding of certain cancers and complex congenital disorders by illuminating how BRD4, a protein that scientists have studied for years, directs the spatial organization of DNA within the nucleus of the cell, a function critical for stem cell differentiation into muscle cells.

7 Oct 2021

Specialized cells that keep the heart beating have ability to regenerate after birth, study reveals

Specialized cells that conduct electricity to keep the heart beating have a previously unrecognized ability to regenerate in the days after birth, a new study in mice by UT Southwestern researchers suggests.

7 Oct 2021

After 5 months, Pfizer-BioNTech COVID vaccine remains highly protective against hospitalization and death

The study "Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study" is published in the journal The Lancet.

7 Oct 2021

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

A new study published on the medRxiv* preprint server focused on a patient with a persistent symptomatic viral infection for over a year. Researchers amplified sub-genomic transcripts for the E gene (sgE) using nasopharyngeal samples of the patient infected with SARS-CoV-2 over the course of 335 days.

6 Oct 2021

Heroin overdose deaths more likely to occur shortly after hospital discharge

Drug-related deaths are four times more likely to occur in the two days after hospital discharge than at any other time among users of opioids such as heroin, according to research led by UCL, Public Health England (PHE) and King's College London.

6 Oct 2021

New model can predict the risk of airborne COVID-19 infection in offices and schools

As more UK workers and students return to offices and schools, a new model has been developed to predict the risk of airborne COVID-19 infection in such environments.

6 Oct 2021

Study shows new antibody resistant variants can emerge in patients treated with monoclonal antibodies

A new study, published on the medRxiv* preprint server, suggested that selective pressures induced by the administration of monoclonal antibodies (Bamlanivimab) may require increased genomic surveillance to identify and control the spread of therapy-induced variants.

6 Oct 2021

Tiny bubbles show promise for reducing inflammation

Scientists hope that tiny sacs of material excreted by cells - so-called extracellular vesicles - can be used to deliver drugs inside the body. Researchers at Karolinska Institutet now show that these nano-bubbles can transport protein drugs that reduce inflammation caused by different diseases.

6 Oct 2021

Scientists make inroads into creating an atlas of the mouse brain

It takes billions of cells to make a human brain, and scientists have long struggled to map this complex network of neurons.

6 Oct 2021

Racial disparities in lung cancer survival rates can be mitigated by providing equal treatment access

Although Black lung cancer patients are more likely to die from their disease than white patients, they have better outcomes than whites when treated with immunotherapies that are now considered the best standard of care.

6 Oct 2021

Neuroscientists unveil detailed atlas of brain cells

When you clicked to read this story, a band of cells across the top of your brain sent signals down your spine and out to your hand to tell the muscles in your index finger to press down with just the right amount of pressure to activate your mouse or track pad.

6 Oct 2021

Novel proteomics approach predicts severe COVID-19 outcomes

Researchers in the United States, Canada, and the UK have developed a potential new approach to predicting severe and critical outcomes among patients with coronavirus disease 2019 (COVID-19).

6 Oct 2021

Machine learning and high-powered microscopes provide detailed snapshots of cells' inner machinery

Open any introductory biology textbook, and you'll see a familiar diagram: A blobby-looking cell filled with brightly colored structures – the inner machinery that makes the cell tick.

6 Oct 2021

COVID-19 lockdown restrictions may increase preterm stillbirths

Researchers in Australia have reported that pregnant women in Melbourne were more likely to have a preterm stillbirth during the period when coronavirus disease 2019 (COVID-19) lockdown restrictions were imposed on the city, than they were during the corresponding period one and two years prior.

6 Oct 2021

Research News and Research

Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Massage can enhance healing and strength of muscles, study finds

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Protecting the ozone layer could prevent cancer cases and other diseases in the U.S

Teaching magic tricks to kids with ADHD can enhance their feelings of self-esteem and confidence

Mouse brain atlas may help understand the complex circuits of the human brain

Study illuminates how BRD4 protein directs the spatial organization of DNA within cell nucleus

Specialized cells that keep the heart beating have ability to regenerate after birth, study reveals

After 5 months, Pfizer-BioNTech COVID vaccine remains highly protective against hospitalization and death

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

Heroin overdose deaths more likely to occur shortly after hospital discharge

New model can predict the risk of airborne COVID-19 infection in offices and schools

Study shows new antibody resistant variants can emerge in patients treated with monoclonal antibodies

Tiny bubbles show promise for reducing inflammation

Scientists make inroads into creating an atlas of the mouse brain

Racial disparities in lung cancer survival rates can be mitigated by providing equal treatment access

Neuroscientists unveil detailed atlas of brain cells

Novel proteomics approach predicts severe COVID-19 outcomes

Machine learning and high-powered microscopes provide detailed snapshots of cells' inner machinery

COVID-19 lockdown restrictions may increase preterm stillbirths

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