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Toxins in Danish mushroom are effective against cancer cells

Researchers at the University of Copenhagen have explored the active principles of a Danish mushroom and found that some of the substances it contains are particularly toxic towards cancer cells. The goal is to synthesise and refine substances in the mushroom that may be useful in future drug development.

9 Dec 2011

Galectin Therapeutics to initiate GM-CT-01 Phase 1/2 combination study in advanced MM

Galectin Therapeutics, the Cancer Centre at the Cliniques universitaires Saint-Luc and the Ludwig Institute for Cancer Research (LICR) announced today that they will initiate a Phase 1/2 safety and efficacy trial testing a novel treatment combination in patients with advanced metastatic melanoma.

9 Dec 2011

Toyota's lean approach might be beneficial to medical procedures

Japanese vehicle manufacturer, Toyota, is well-known for developing the principles of so-called "lean manufacturing". Research published in the International Journal of Technology Management suggests that the lean approach might also be beneficial to medical procedures, making hospitals more efficient and cut waiting lists.

9 Dec 2011

First Edition: December 8, 2011

In today's headlines, reports about the HHS decision on the Plan B morning after pill, as well as the latest progress reports from Capitol Hill on the payroll tax break extension and the doc fix.

8 Dec 2011

Race, ethnicity, and insurance status influence follow-up care

According to the results of a new study published in the Journal of the American College of Surgeons, African-Americans, Hispanics and uninsured patients use fewer post-hospitalization services after traumatic injury, including home health care, skilled nursing care, and rehabilitation.

8 Dec 2011

Zoledronic acid increases bone mineral density, reduces recurrence in postmenopausal breast cancer

The addition of zoledronic acid to adjuvant endocrine therapy increased bone mineral density and reduced the risk for disease recurrence among postmenopausal women with early hormone receptor-positive breast cancer, according to new data from the ZO-FAST trial.

8 Dec 2011

Cubist, Adolor announce results of initial tender offer

Cubist Pharmaceuticals, Inc. and Adolor Corporation today announced the results of Cubist's initial tender offer to purchase all of the outstanding shares of common stock of Adolor.

8 Dec 2011

Heart patients may experience fewer traumas with new invention

Heart patients may experience "a lot less" trauma with a new invention to mend leaky valves with minimum cutting, says inventor James Gammie, MD, an associate professor at the University of Maryland (UM) School of Medicine.

8 Dec 2011

NSU's College of Dental Medicine to provide care for persons with special needs

Nova Southeastern University's (NSU) College of Dental Medicine recently received a two-year, $437, 616 grant from the DentaQuest Foundation to train practicing dentists in Florida to provide care for persons with special needs.

8 Dec 2011

Two new research studies to help colicky infant and their parents

The wail of a colicky baby can send parents into near panic and cause sleepless nights for all. Now, two innovative research studies are being conducted at the new UT Physicians Colic Clinic at The University of Texas Health Science Center at Houston (UTHealth) to help both crying babies and their worried parents.

8 Dec 2011

Montefiore recognized among Leapfrog's 2011 Top Hospitals list

Montefiore Medical Center was recognized yesterday as one of the nation's 2011 Top Hospitals by The Leapfrog Group, a coalition of public and private purchasers of employee health coverage dedicated to improving healthcare safety, quality and affordability. Of the 65 hospitals chosen from nearly 1200 nationwide that participated in the annual survey, Montefiore was one of only two hospitals named from New York State.

8 Dec 2011

Treating 'brain tsunamis' could stop many victims of major head injury from further damage

Treating 'brain tsunamis' or 'killer waves' could stop many victims of major head injury from suffering additional brain damage, a study published in Lancet Neurology has found.

8 Dec 2011

Massive and consistent changes in inflammatory gene expression seen in trauma, burns

Serious traumatic injuries, including major burns, set off a "genomic storm" in human immune cells, altering around 80 percent of the cells' normal gene expression patterns. In a report to appear in the December Journal of Experimental Medicine, members of a nationwide research collaborative describe the initial results of their investigation into the immune system response to serious injury, findings which have overturned some longstanding assumptions.

8 Dec 2011

Cedars-Sinai neurosurgeon seals off wide-neck aneurysm with new device

As Stephanie Weiss was coming to grips with the news she had two large and three small aneurysms in her brain, the Los Angeles independent travel consultant was told there was no minimally invasive way to treat at least one of the defects: a wide-neck aneurysm. She would have to undergo open-brain surgery.

8 Dec 2011

BCX4945 proves effective at clearing malaria infections

An antimalarial agent developed by researchers at Albert Einstein College of Medicine of Yeshiva University proved effective at clearing infections caused by the malaria parasite most lethal to humans - by literally starving the parasites to death. The novel research, carried out on a small number of non-human primates, could bolster efforts to develop more potent therapies against one of the world's leading killers.

8 Dec 2011

ISARIC aims to prepare clinical research community for next influenza pandemic

An international consortium aimed at ensuring that the clinical research community is better prepared for the next influenza pandemic or other rapidly emerging public health threat is launched today by leading funders of medical research from across the globe.

8 Dec 2011

Euthymics presents EB-1020 preclinical data on ADHD at ACNP annual meeting

Euthymics Bioscience, Inc. today announced that it has presented preclinical data demonstrating that EB-1020, a next-generation product candidate for adult attention deficit/hyperactivity disorder (ADHD), may be effective for treating ADHD without the burden of drug abuse liability.

8 Dec 2011

Women & Infants the first to offer digital breast tomosynthesis in southeastern New England

There is still a one in eight lifetime risk that a woman will develop breast cancer, and the best tool against the disease remains early detection. Now, Women & infants Hospital of Rhode Island has taken the breast cancer battle to the next level with the installation of the most advanced imaging technology available, called digital breast tomosynthesis.

8 Dec 2011

State roundup: Aetna suing over Mich. BCBS hospital deals; ACLU threatens Ohio abortion suit

The latest challenge was a lawsuit filed Tuesday in Detroit's federal court by insurance giant Aetna, one of the nation's largest health plans, with 35 million members. The suit alleges a violation of federal antitrust laws, claiming the Blues raised rates for Michigan consumers over the last four years and used the money to reward hospitals with higher payments if they charged Blues' competitors the same or higher rates.

8 Dec 2011

Researchers sequence entire transcriptome of mouse neural retina

The population of Eric Morrow's seminar "Neurogenetics and Disease" comprises mainly undergraduates who were skipping down the halls of their elementary schools when the first drafts of human genome sequences were published. When Morrow, assistant professor of biology, recently asked the class how to find the mutation behind a disease, a hand shot up in the back of the class to signal the answer: "Sequence the patient's genome."

8 Dec 2011