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New biological technique may provide better, longer-lasting joint function

According to the Agency for Healthcare Research and Quality, more than 300,000 total hip replacements are performed in the United States each year. The procedure reduces pain and restores mobility. However, for younger, more active patients, an artificial hip has a limited lifetime and usually requires restricted activity.

23 Feb 2016

MDI Biological Laboratory scientist identifies potential drug therapy to reverse peripheral nerve damage

The Mount Desert Island Biological Laboratory has announced that assistant professor Sandra Rieger, Ph.D., has identified two drugs that could potentially be used to reverse peripheral nerve damage, or peripheral neuropathy, resulting from chemotherapy treatment for ovarian, breast, lung, pancreas and other cancers. The drugs also have potential applications for the treatment of peripheral nerve damage caused by diabetes, traumatic injuries and other conditions.

23 Feb 2016

Black, white Americans cope with pain differently

Researchers led by Adam T. Hirsh of the School of Science at Indiana University-Purdue University Indianapolis report that black and white Americans cope with pain differently and that blacks employ pain coping strategies more frequently than whites. The IUPUI review and analysis of 19 studies is the first to examine the entire published literature and quantify the relationship between race and the use of pain-coping strategies.

23 Feb 2016

Giving feedbacks to GPs could cut unnecessary prescriptions of antibiotics

Sending general practitioners (GPs) in England a letter giving feedback on their antibiotic prescribing habits could cut unnecessary prescriptions of antibiotics, according to the first nationwide randomised trial of its kind involving over 1500 GP practices, published in The Lancet.

23 Feb 2016

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Pfizer Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication expanding the use of IBRANCE (palbociclib) 125mg capsules, Pfizer’s metastatic breast cancer therapy.

23 Feb 2016

Researchers Pinpoint Potential Enzyme For T-Cell Leukemia Treatment

For the first time, researchers at Boston University have shown that T-cell leukemia cells use a particular cycle, called the TCA or Kreb cycle, to support their growth and survival.

23 Feb 2016

Cardiac clot-busting drug decreases mortality in hemorrhagic stroke patients

Reporting on the results of a phase III international clinical trial, Johns Hopkins Medicine physicians say use of a cardiac clot-busting drug to treat strokes that cause brain bleeding safely decreased the death rate in patients by 10 percent, compared to a control group receiving saline.

23 Feb 2016

Pitt experts lead gene therapy clinical trial in Parkinson's disease patients

Experts at the University of Pittsburgh School of Medicine are leading the second arm of a clinical trial using gene therapy to relieve the symptoms of tremor and mobility impairment in patients with Parkinson's disease.

23 Feb 2016

Uninsured children subject to more insufficient levels of care, finds USC researchers

Researchers at the Keck School of Medicine at the University of Southern California (USC) examined medical home trends in children's primary care from 2003 to 2012 and found that while this specific healthcare model has improved children's primary care overall, certain aspects of children's patient care experience have worsened. Moreover, upon analyzing various at-risk profiles, the team found that uninsured children were subject to more insufficient levels of care.

23 Feb 2016

UA College of Pharmacy assistant professor developing dry powder inhalers to treat pulmonary diseases

Heidi M. Mansour, PhD, assistant professor in the University of Arizona College of Pharmacy, is working to develop advanced dry powder inhalers to treat and prevent pulmonary diseases.

23 Feb 2016

Losing just 5% of weight has significant health benefits for patients with obesity

For patients with obesity trying to lose weight, the greatest health benefits come from losing just 5 percent of their body weight, according to a new study at Washington University School of Medicine in St. Louis.

23 Feb 2016

UCSF study finds specific molecular-genetic mechanism that links sleep and seasonal depression

A newly discovered human gene mutation appears to contribute both to unusual sleep patterns and to heightened rates of seasonal depression, according to new research from UC San Francisco.

23 Feb 2016

Light-to-moderate drinking can be good for your heart

Drinking a little alcohol every day may be part of a healthy lifestyle, according to Imre Janszky, a professor of social medicine at the Norwegian University of Science and Technology. He says alcohol does more good than harm for your heart when consumed in moderation.

23 Feb 2016

SIFT 4G software can lead to faster genome analysis

An international team of scientists, led by researchers from A*STAR's Genome Institute of Singapore (GIS) and the Bioinformatics Institute (BII), have developed SIFT 4G (SIFT for Genomes) - a software that can lead to faster genome analysis.

23 Feb 2016

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Namandje Bumpus, Ph.D., and Jordan Green, Ph.D., of the Johns Hopkins University School of Medicine are among 105 winners of Presidential Early Career Awards for Scientists and Engineers, which were announced by the White House on Feb. 18.

23 Feb 2016

Study identifies new mechanism for controlling HIV replication

Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus.

23 Feb 2016

Increasing medication adherence: an interview with Dr Alejandro (Alex) Jaimes

Adherence applies to multiple levels of healthcare. Before a drug goes on the market it has to undergo testing in clinical trials: participants take the study drug and report how well the drug works, along with any side effects.

22 Feb 2016

Patient enrollment completed in vepoloxamer Phase 3 study for treatment of sickle cell disease

Mast Therapeutics, Inc., a biopharmaceutical company developing novel, clinical-stage therapies for sickle cell disease and heart failure today announced that it has completed patient enrollment in its Phase 3 clinical study of vepoloxamer for the treatment of patients with sickle cell disease experiencing vaso-occlusive crisis, known as the EPIC study.

22 Feb 2016

Diabetes researchers develop novel technique to monitor insulin resistance

Diabetes researchers at Sweden's Karolinska Institutet have developed a novel technique that makes it possible to monitor insulin resistance in a non-invasive manner over time in mice. The new method, presented in the journal Scientific Reports, can be used to assess insulin resistance during progression and intervention of metabolic diseases.

22 Feb 2016

Understanding risk factors that contribute to childhood obesity

As the rate of obesity in the U.S. population has risen dramatically, more and more children are becoming overweight at younger and younger ages. Understanding the factors that contribute to childhood obesity and identifying ways to prevent its development are critical to stemming the historically high prevalence of childhood obesity and of associated health problems like type 2 diabetes.

22 Feb 2016

Medicine News and Research

New biological technique may provide better, longer-lasting joint function

MDI Biological Laboratory scientist identifies potential drug therapy to reverse peripheral nerve damage

Black, white Americans cope with pain differently

Giving feedbacks to GPs could cut unnecessary prescriptions of antibiotics

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Researchers Pinpoint Potential Enzyme For T-Cell Leukemia Treatment

Cardiac clot-busting drug decreases mortality in hemorrhagic stroke patients

Pitt experts lead gene therapy clinical trial in Parkinson's disease patients

Uninsured children subject to more insufficient levels of care, finds USC researchers

UA College of Pharmacy assistant professor developing dry powder inhalers to treat pulmonary diseases

Losing just 5% of weight has significant health benefits for patients with obesity

UCSF study finds specific molecular-genetic mechanism that links sleep and seasonal depression

Light-to-moderate drinking can be good for your heart

SIFT 4G software can lead to faster genome analysis

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Study identifies new mechanism for controlling HIV replication

Increasing medication adherence: an interview with Dr Alejandro (Alex) Jaimes

Patient enrollment completed in vepoloxamer Phase 3 study for treatment of sickle cell disease

Diabetes researchers develop novel technique to monitor insulin resistance

Understanding risk factors that contribute to childhood obesity

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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