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Small minority of cancer cells contribute to growth and metastasis of tumours

New research shows that a small minority of cancer cells in neuroendocrine tumours of the pancreas contribute to the overall growth and metastasis of the tumour. This discovery was made by a research group at Lund University, in collaboration with researchers at Karolinska Institutet, in Sweden.

3 Feb 2016

Flexible duty hours safe for patients and beneficial for surgical residents

A new landmark national study led by Northwestern Medicine showed allowing surgical residents the flexibility to work longer hours in order to stay with their patients through the end of an operation or stabilize them during a critical event did not pose a greater risk to patients.

3 Feb 2016

Height affects risk of major non-communicable diseases

Height is largely genetically determined, but in recent decades the height of children and adults has steadily increased throughout the world: In adulthood the children are almost always significantly taller than their parents.

3 Feb 2016

New study finds steep decline in basic science publications

A new study has found a steep decline in the number of scholarly papers about basic science published in leading medical journals in the last 20 years.

3 Feb 2016

Study finds no evidence of genetic overlap between schizophrenia risk and subcortical brain volumes

Over the last decade, important contributions to our understanding of schizophrenia have come from two different types of studies. Neuroimaging studies have found that certain parts of the brain, such as the hippocampus and amygdala, are smaller in people with schizophrenia - a devastating psychiatric illness with high heritability.

3 Feb 2016

Pluripotent stem cells could serve as valuable model for understanding Andersen's syndrome

Successful reprogramming of muscle cells derived from biopsies of patients with Andersen's syndrome (AS) led to the formation of induced pluripotent stem (iPS) cells that can serve as a valuable model for understanding the cause of this rare disorder and discovering novel therapies.

3 Feb 2016

New approach to investigate how neurodevelopment influences diseases in adulthood

The Research Training Group, which builds on translational research training programmes and research structures such as the Molecular Medicine degree programme and the Interdisciplinary Centre for Clinical Research, will work on areas where basic research and clinical practice overlap. It will bring together 20 doctoral candidates from the natural sciences and 28 from medicine.

3 Feb 2016

New gene cut-and-paste methods help correct disease-causing mutation in animal model

For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected.

3 Feb 2016

New drug cocktail may show promise in NSCLC patients

A drug approved by the Food and Drug Administration for melanoma in combination with a common cholesterol-lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sinai.

3 Feb 2016

New Brown School study examines health-related quality of life for breast cancer survivors

Breast cancer takes a daunting toll on all women, but it hits younger women especially hard, finds a new study from the Brown School at Washington University in St. Louis.

3 Feb 2016

Genetic profiling ‘feasible’ for paediatric cancer patients

Research published in JAMA Oncology demonstrates that tumour and germline molecular profiling is feasible in paediatric cancer patients and can have actionable findings.

2 Feb 2016

MYB-QKI fusion gene that drives pediatric low-grade gliomas poses a triple threat

Oncology researchers have discovered that an abnormal fused gene that drives pediatric brain tumors poses a triple threat, operating simultaneously through three distinct biological mechanisms—the first such example in cancer biology.

2 Feb 2016

Immunological changes during pregnancy may influence response to influenza vaccination

In a study to be presented on Feb. 5 in an oral concurrent session at 1:15 p.m. EST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in Atlanta, researchers will present findings from a study titled, T-follicular helper (Thf) cell expansion varies by trimester after influenza vaccination in pregnancy.

2 Feb 2016

Use of antenatal steroids during late preterm delivery prevents neonatal respiratory complications

In a study to be presented on Feb. 4 in the oral plenary session at 8 a.m. EST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in Atlanta, researchers with the Eunice Kennedy Shriver National Institute of Child Health and Human Development and Maternal-Fetal Medicine Units Network found that the administration of antenatal steroids in pregnancies at risk for late preterm delivery prevents respiratory and other neonatal complications.

2 Feb 2016

Researchers use new method to assess quality of colonoscopies performed in outpatient facilities

Colonoscopies are now a routine preventive diagnostic test for millions of Americans each year. While rates are low, complications like perforation, bleeding, and anesthesia-related heart failure can occur. Yale School of Medicine researchers have now developed a quality measure that uses follow-up hospital visits to track the variation in colonoscopy quality among outpatient facilities.

2 Feb 2016

New process for altering ingredients in sunscreen enables the body to produce vitamin D

For the first time researchers have developed a process for altering the ingredients in a sunscreen that does not impact its sun protection factor (SPF), but does allow the body to produce vitamin D. The findings, published in the peer reviewed journal PLOS ONE, has led to the production of a new sunscreen called Solar D.

2 Feb 2016

New way to more efficiently deliver CRISPR/Cas9 therapeutic to mice with Tyrosinemia type I

University of Massachusetts Medical School researchers have found a way to more efficiently delivery a CRISPR/Cas9 therapeutic to adult mice with the metabolic disease Tyrosinemia type I that may also prove to be safer for use in humans.

2 Feb 2016

Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

The mechanisms underlying the stability and plasticity of neural circuits in the hippocampus, the part of the brain responsible for spatial memory and the memory of everyday facts and events, has been a major focus of study in the field of neuroscience. Understanding precisely how a "healthy" brain stores and processes information is crucial to preventing and reversing the memory failures associated with Alzheimer's disease (AD), the most common form of late-life dementia.

2 Feb 2016

Coordinated specialty care more cost-effective for young people with first episode psychosis

New analysis from a mental health care study shows that "coordinated specialty care" (CSC) for young people with first episode psychosis is more cost-effective than typical community care. Cost-effectiveness analysis in health care is a way to compare the costs and benefits of two or more treatment options.

2 Feb 2016

Study reveals increased mortality risk following hypertensive disease of pregnancy

In a study to be presented on Feb. 5 at 8 a.m. EST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in Atlanta, researchers will present findings from a study titled, Long-term mortality risk following hypertensive disease of pregnancy (HDP).

2 Feb 2016

Medicine News and Research

Small minority of cancer cells contribute to growth and metastasis of tumours

Flexible duty hours safe for patients and beneficial for surgical residents

Height affects risk of major non-communicable diseases

New study finds steep decline in basic science publications

Study finds no evidence of genetic overlap between schizophrenia risk and subcortical brain volumes

Pluripotent stem cells could serve as valuable model for understanding Andersen's syndrome

New approach to investigate how neurodevelopment influences diseases in adulthood

New gene cut-and-paste methods help correct disease-causing mutation in animal model

New drug cocktail may show promise in NSCLC patients

New Brown School study examines health-related quality of life for breast cancer survivors

Genetic profiling ‘feasible’ for paediatric cancer patients

MYB-QKI fusion gene that drives pediatric low-grade gliomas poses a triple threat

Immunological changes during pregnancy may influence response to influenza vaccination

Use of antenatal steroids during late preterm delivery prevents neonatal respiratory complications

Researchers use new method to assess quality of colonoscopies performed in outpatient facilities

New process for altering ingredients in sunscreen enables the body to produce vitamin D

New way to more efficiently deliver CRISPR/Cas9 therapeutic to mice with Tyrosinemia type I

Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

Coordinated specialty care more cost-effective for young people with first episode psychosis

Study reveals increased mortality risk following hypertensive disease of pregnancy

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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