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Transgenic rat model may provide new insights into cerebral amyloid angiopathy

In a report in The American Journal of Pathology investigators describe the generation of a successful novel transgenic rat model that accumulates amyloid specifically in brain blood vessels and strongly mimics many of the associated detrimental changes that are observed in humans - a condition known as cerebral amyloid angiopathy, which is also commonly observed in Alzheimer disease.

13 Nov 2018

Multidisciplinaryresearch teams selected to study age-related brain disorders

Could our blood hold the molecular secrets to a fountain of youth, preventing age-related brain disorders? Are brain aging and Alzheimer's disease caused by a failure of interconnected systems in our bodies, triggering a domino-like cascade of disease? Can targeting the red blood cells and blood vessels jointly keep our brains healthy and prevent dementia?

12 Nov 2018

Mild exposure to single blast can induce meaningful pathogenic effects, study shows

As many as 300,000 United States service members deployed to Iraq and Afghanistan since 2001 have suffered traumatic brain injury due to explosions. The vast majority of these blast-induced traumatic brain injuries, or bTBIs, were classified as mild.

12 Nov 2018

Salk researchers receive $19.2 million to unravel mysteries of age-related cognitive decline

A team of Salk Institute researchers led by President Rusty Gage has been awarded $19.2 million over eight years by the American Heart Association-Allen Initiative in Brain Health and Cognitive Impairment to investigate mechanisms underlying Alzheimer's disease and aging-related cognitive decline and uncover new therapies.

12 Nov 2018

Scientists solve 125-year-old mystery of the brain, uncover potential treatment for epilepsy

Scientists at the Virginia Tech Carilion Research Institute have solved a 125-year-old mystery of the brain, and, in the process, uncovered a potential treatment for acquired epilepsy.

9 Nov 2018

Sussex scientists develop a piece of hardware to show how brains function

Scientists at the University of Sussex have developed a piece of hardware to demonstrate how our brains function, as part of a growing range of equipment which uses DIY and 3D printable models to open up access to science education.

9 Nov 2018

Neuroscientists receive $16.75 million from BRAIN Initiative to decipher the brain's visual system

The BRAIN Initiative has awarded $16.75 million to a team of neuroscientists charged with deciphering the primary visual cortex, a few hundred million brain cells that play a key role in making sense of what the eye sees.

9 Nov 2018

Targeting one brain region with alternating current could decrease symptoms of chronic pain

For the first time, researchers at the UNC School of Medicine showed they could target one brain region with a weak alternating current of electricity, enhance the naturally occurring brain rhythms of that region, and significantly decrease symptoms associated with chronic lower back pain.

9 Nov 2018

Researchers elucidate new rules of connectivity of neurons in the neocortex

As the adage goes "neurons that fire together, wire together," but a new paper published today in Neuron demonstrates that, in addition to response similarity, projection target also constrains local connectivity.

9 Nov 2018

Learning familiar faces through social interactions reduces variability in face recognition

A Dartmouth study finds that recognition of faces varies by where they appear in the visual field and this variability is reduced by learning familiar faces through social interactions.

9 Nov 2018

Studying sensory neurons could provide new insights to treat ALS

Virginia Tech Carilion Research Institute scientists have shown that mutations in specific genes that destroy motor neurons and thereby cause the devastating effects of amyotrophic lateral sclerosis-- also known as ALS or Lou Gehrig's disease -- also attack sensory neurons.

9 Nov 2018

Maximal longevity in species can be better explained by number of neurons in the brain

Scientists have thought that the main determinant of maximal longevity in warm-blooded animals--which varies from as little as 2 to as many as 211 years--is a species' metabolic rate, which is inversely related to body size. It follows that at 2 years of life, small animals with high metabolic rates are already old, but large animals with low metabolic rates are still young.

9 Nov 2018

GW study examines impact of nervous system on non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease, the accumulation of fat in the liver of people who drink little or no alcohol, affects 1 in 3 Americans. NAFLD is a significant risk factor for Type 2 diabetes, insulin resistance, and hepatic carcinoma, and incidence of the disease is increasing with the growing obesity epidemic in the United States.

8 Nov 2018

Study of gaze fixation in monkeys reveals role of dopamine neurons in response inhibition

A University of Tsukuba-led study of gaze fixation in monkeys and their refusal to redirect the gaze onto a target in return for a reward reveals that dopamine neurons are key to inhibiting preplanned actions.

8 Nov 2018

Study could provide novel treatment strategy for potentially blinding problem

An enzyme known to help our liver get rid of ammonia also appears to be good at protecting our retina, scientists report.

8 Nov 2018

Interaction strength and time delays can change how synchronization appears and develops

In physical, biological and technological systems, the time that a system's components take to influence each other can affect the transition to synchronization, an important finding that improves understanding of how these systems function, according to a study led by Georgia State University.

8 Nov 2018

New prosthetic hand system restores 'feeling' to a person with upper limb amputation

Arizona State University researcher James Abbas is part of a multi-institutional research team that has developed a new prosthetic hand system with a fully implanted, wirelessly controlled neurostimulator that has restored "feeling" to a person with a hand amputation.

7 Nov 2018

Nasal delivery of leptin hormone may help ease breathing problems during sleep

Experimenting with mice, Johns Hopkins Medicine researchers have added to evidence that a hormone best known for helping regulate hunger and body weight might also ease breathing problems experienced during sleep more effectively when given through the nose.

7 Nov 2018

Rats and humans share ability to selectively forget distracting memories

Our ability to selectively forget distracting memories is shared with other mammals, suggests new research from the University of Cambridge.

7 Nov 2018

Researchers develop electroencephalography-based test to objectively measure pain

If you've ever visited the emergency department with appendicitis, or you're one of the 100 million U.S. adults who suffer from chronic pain, you're familiar with a row of numbered faces, with expressions from smiling to grimacing, used to indicate pain levels.

6 Nov 2018

Neurons News and Research

Transgenic rat model may provide new insights into cerebral amyloid angiopathy

Multidisciplinaryresearch teams selected to study age-related brain disorders

Mild exposure to single blast can induce meaningful pathogenic effects, study shows

Salk researchers receive $19.2 million to unravel mysteries of age-related cognitive decline

Scientists solve 125-year-old mystery of the brain, uncover potential treatment for epilepsy

Sussex scientists develop a piece of hardware to show how brains function

Neuroscientists receive $16.75 million from BRAIN Initiative to decipher the brain's visual system

Targeting one brain region with alternating current could decrease symptoms of chronic pain

Researchers elucidate new rules of connectivity of neurons in the neocortex

Learning familiar faces through social interactions reduces variability in face recognition

Studying sensory neurons could provide new insights to treat ALS

Maximal longevity in species can be better explained by number of neurons in the brain

GW study examines impact of nervous system on non-alcoholic fatty liver disease

Study of gaze fixation in monkeys reveals role of dopamine neurons in response inhibition

Study could provide novel treatment strategy for potentially blinding problem

Interaction strength and time delays can change how synchronization appears and develops

New prosthetic hand system restores 'feeling' to a person with upper limb amputation

Nasal delivery of leptin hormone may help ease breathing problems during sleep

Rats and humans share ability to selectively forget distracting memories

Researchers develop electroencephalography-based test to objectively measure pain

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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