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Prox1 gene plays a critical role in formation and maintenance of lymphatic system

A century after the valves that link the lymphatic and blood systems were first described, St. Jude Children's Research Hospital scientists have detailed how those valves form and identified a gene that is critical to the process.

15 Nov 2011

Researchers examine optimal timing for carotid artery stenting after TIA or stroke

A recent study found no significant difference in the outcome for patients who received carotid artery stenting (CAS) at more than 30 days post-transient ischemic attack (TIA) or stroke versus those who received CAS at 30 days or less post-event.

15 Nov 2011

State roundup: Md.'s medical home; N.Y. malpractice action; Texas nursing homes

Instead of a doctor seeing patients mostly when they're sick - and the physician is getting paid for that visit or service - this program gives financial rewards to practices that use a team of doctors, nurses and other staff to treat the whole person on a continuing basis, not just for one illness. ... The state initiative is among dozens of public and private experiments across the country that are trying to fundamentally change the way doctors practice medicine.

15 Nov 2011

New non-invasive measurement may predict people at risk of heart failure

A new study from researchers at the Perelman School of Medicine at the University of Pennsylvania and collaborators at various institutions, presented at the 2011 American Heart Association Scientific Sessions, shows that a novel, non-invasive measurement of arterial wave reflections may be able to predict who is most at risk for heart failure.

15 Nov 2011

Lentigen, UH Case Medical Center initiate LG631 Phase I trial in glioblastoma

University Hospitals (UH) Case Medical Center, Case Western Reserve University School of Medicine and Lentigen Corporation announced today the initiation of a novel Phase I clinical trial of LG631 gene therapy for the protection of hematopoietic stem cells (HSCs) from the dose limiting toxicity of chemotherapy with Temodar.

15 Nov 2011

Possible link between norovirus and food allergies

Researchers at the Medical College of Wisconsin have found a possible link between norovirus, a virus that causes "stomach flu" in humans, and food allergies.

15 Nov 2011

Mary Ann Liebert to launch Disruptive Science and Technology

Mary Ann Liebert, Inc., publishers announces the launch of Disruptive Science and Technology, a highly innovative, bimonthly peer-reviewed journal that seeks to publish game-changing research that has the potential to significantly improve human health, well-being, and productivity.

14 Nov 2011

New clues about connections among fat, inflammation and insulin resistance

In a new study, scientists report that they substantially curbed weight gain, improved metabolism, and improved the efficacy of insulin in mice by engineering them to express a specific human enzyme in their fat tissue. Although the obesity prevention came at the significant cost of widespread inflammation, the research offers new clues about the connections among obesity, insulin resistance and type 2 diabetes, and inflammation.

14 Nov 2011

Link between hysterectomy and early menopause among younger women

In a finding that confirms what many obstetricians and gynecologists suspected, Duke University researchers report that younger women who undergo hysterectomies face a nearly two-fold increased risk for developing menopause early.

14 Nov 2011

Fetal stem cells play an important role in inducing maternal cardiac repair

Researchers from Mount Sinai School of Medicine have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury.

14 Nov 2011

Herat risk screening inadequate in high school sports physicals: Study

Following incidents of deaths of high school athletes who collapse suddenly during practice or a game, new guidelines for screening prep athletes for hidden heart problems before the start of a season had been in place since 1996. About one of every 30,000 to 50,000 high school athletes dies each year from cardiac arrest.

14 Nov 2011

Fiber from whole grains reduces risk of bowel cancer: Study

The researchers from Britain and the Netherlands found that the more total dietary fiber and cereal fiber people consumed, the lower their colorectal cancer risk. For example, people who consumed an extra 90 grams of fiber from whole grains a day also had a 20 percent lower risk of colorectal cancer, according to the British Medical Journal review.

14 Nov 2011

Sugary drinks raise risk of heart disease in women: Study

A new study shows that women who take sugared beverages every day may be raising their risk for heart disease, even if their habit is not packing on the pounds. The researchers say the drinks could be anything - sweet tea, soda, or coffee drinks that look like desserts.

14 Nov 2011

Sexual and physical abuse of girls raises risk of heart disease: Study

A new study finds that women who have experienced repeated episodes of sexual abuse during childhood or adolescence appear to have a 62% greater risk for heart disease. Further, severe physical abuse was also associated with a 45% increased risk for cardiovascular or CV events

14 Nov 2011

Bayer and J&J’s blood thinner drug triumphs at late phase clinical trial

Drug makers Bayer AG and Johnson & Johnson’s new blood clot preventing drug can provide life-saving benefits at very low doses in patients who suffer from acute coronary syndrome finds a new clinical trial.

14 Nov 2011

Stem cell bandage human clinical trial for torn meniscal cartilage

The company behind a pioneering stem cell bandage, believed to be the world's first adult and autologous (patient's own) stem cell treatment designed to heal torn meniscal cartilage, can now take the technology to human clinical trials thanks to an investment from one of the UK's most successful entrepreneurs.

14 Nov 2011

Study confirms impact of high-quality CPR on improving sudden cardiac arrest survival rates

ZOLL Medical Corporation, a manufacturer of medical devices and related software solutions, announced today that results from the CIRC trial were presented at the American Heart Association (AHA) 2011 Resuscitation Science Symposium (ReSS) this weekend in Orlando.

14 Nov 2011

Fears about ICD shock during sex leads to performance problems in heart patients

Adults with congenital heart disease and implanted cardioverter defibrillators (ICDs) often have a high level of fear and anxiety about the device delivering a shock during sex - resulting in sexual performance problems, according to research (Abstract 14165) presented at the American Heart Association's Scientific Sessions 2011.

14 Nov 2011

Cadence proposes $75M underwritten public offering of common stock

Cadence Pharmaceuticals, Inc. today announced its intention to offer and sell $75 million worth of shares of its common stock in an underwritten public offering.

14 Nov 2011

Bone-marrow derived cells do not improve heart function after attack

NIH-funded trial shows that therapy with bone-marrow derived cells does not improve heart function after six months; future clinical benefits still possible.

14 Nov 2011