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CTTV launches new web platform for identifying therapeutic targets

The Centre for Therapeutic Target Validation (CTTV) has launched a new web platform for life-science researchers that helps them identify therapeutic targets for new and repurposed medicines. Today's launch underscores the CTTV's commitment to share its data openly to benefit the broader scientific community.

8 Dec 2015

Penile prostheses benefit men with erectile dysfunction

Most men who receive penile prostheses are very satisfied with the implants, indicating that the intervention is a valid treatment for erectile dysfunction.

8 Dec 2015

Macrophages play key role in maintaining healthy arteries after inflammation

Researchers from the University of Toronto have found that a specific cell type plays a key role in maintaining healthy arteries after inflammation. It's a discovery that could provide treatment options for cardiovascular disease -- one of the leading causes of death in Canada.

8 Dec 2015

NEK7 enzyme acts as on-off switch in innate immune system

UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection.

8 Dec 2015

First targeted treatment to improve survival of high-risk patients with acute myeloid leukemia

Midostaurin added to standard chemotherapy is the first targeted treatment to improve survival of a high-risk, genetically defined subgroup of patients with acute myeloid leukemia (AML), reported Dr. Richard Stone, of Dana-Farber Cancer Institute, on behalf of the Alliance for Clinical Trials in Oncology group, in a plenary session at the 57th American Society of Hematology Annual Meeting and Exposition in Orlando.

8 Dec 2015

Researchers identify genes that act as brakes to stop development of aggressive type of leukaemia

Genes that act as brakes to stop the development of an aggressive form of leukaemia have been identified by researchers.

8 Dec 2015

Dompé’s investigational biotech molecule receives orphan drug designation for treatment of neurotrophic keratitis

The Dompé biopharmaceutical company announced today that the Committee for Orphan Medicinal Products of the European Medicines Agency (EMA) has officially designated recombinant human Nerve Growth Factor (rhNGF) - the investigational biotech molecule developed by Dompé based on research by Nobel Laureate Rita Levi Montalcini - as an orphan drug for the treatment of neurotrophic keratitis.

8 Dec 2015

Innovative DNA technology enables faster and more effective diagnosis of TB cases

Whole Genome Sequencing is a faster, cheaper and more effective way of diagnosing tuberculosis says a new study published in the journal Lancet Respiratory Medicine.

8 Dec 2015

Study: Certain characteristics can lead to therapy-related leukemia in breast cancer survivors

A new analysis indicates that certain characteristics may increase a breast cancer survivor’s risk of developing leukemia after undergoing chemotherapy and/or radiation. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings are a first step toward finding ways to prevent this serious and potentially life-threatening treatment-related complication.

8 Dec 2015

Takeda presents Phase 3 TOURMALINE-MM1 data for multiple myeloma at ASH 2015

Takeda Pharmaceutical Company Limited today announced results from the TOURMALINE-MM1 trial presented at the 57th Annual Meeting and Exposition of the American Society of Hematology (ASH), showing that treatment with NINLARO (ixazomib) capsules is effective in extending progression free survival (PFS) with a manageable tolerability profile in patients with relapsed and/or refractory multiple myeloma.

8 Dec 2015

Phase 1 BelCHOP study shows belinostat and CHOP chemo regimen as first-line treatment for PTCL

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations and a primary focus in Hematology and Oncology, and Onxeo S.A., an innovative company specializing in the development of orphan oncology drugs, today jointly announced the results from their Phase 1 combination trial of belinostat (Beleodaq) with the CHOP (Cyclophosphamide, Hydroxyl-doxorubicin; Vincristine, and Prednisone) chemotherapy regimen as first-line treatment for newly diagnosed peripheral T-cell lymphoma (PTCL).

8 Dec 2015

Motivational interviewing helps curb prescription opioid abuse among older adults with chronic pain

Prescription opioid abuse has reached epidemic proportions, with more than half of patients being treated for chronic pain reportedly misusing their medication at some point.

8 Dec 2015

XARELTO reduces rates of major bleeding, recurrent blood clots in people with deep vein thrombosis

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced the results from their real-world study XALIA showing that, in people with deep vein thrombosis (DVT), the rates of major bleeding and recurrent blood clots for XARELTO (rivaroxaban) in routine clinical practice were generally consistent with those observed in Phase 3 research.

7 Dec 2015

Hybrid Photon Counting (HPC) technology based on newest ASIC platform for X-ray imaging

DECTRIS Ltd. has announced its Hybrid Photon Counting (HPC) technology based on the newest IBEX ASIC platform for X-ray medical imaging equipment.

7 Dec 2015

New approaches to treating leukemia, lymphoma and myeloma

New, highly targeted treatment approaches for leukemia, lymphoma, and myeloma to be presented today at the 57th American Society of Hematology Annual Meeting and Exposition represent a tremendous expansion of oral and intravenous therapy options for patients with blood cancers.

7 Dec 2015

Yale researchers develop vaccine strategy that reduces risk of flu in cancer patients

Yale Cancer Center researchers have developed a vaccine strategy that reduces the risk of flu infections in cancer patients at highest risk for influenza. The findings were presented Dec. 6 at the 57th annual meeting of the American Society of Hematology in Orlando, Florida.

7 Dec 2015

Risk of dementia decreasing? An interview with Professor Carol Brayne, University of Cambridge

In this analysis we brought together the few European studies that have looked, within geographical areas, at the prevalence or incidence of dementia in the population aged 65 and over.

7 Dec 2015

Age and body fat also contribute to breast cancer risk, say Johns Hopkins researchers

Although several studies suggest that women with denser breast tissue have an increased risk of breast cancer, a new study by Johns Hopkins researchers discredits breast density as a risk factor in and of itself, instead concluding that age and body fat, especially in the upper belly, contribute to the breast cancer seen in many patients.

7 Dec 2015

Cell Therapy Catapult’s 2015 Annual Review highlights key achievements across UK’s health and economy

The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the release of their 2015 Annual Review.

7 Dec 2015

Tips to help lower risk of sports-related concussions

With scholastic sports such as football now in full swing, the potential for head injuries increases. Unfortunately, an estimated 3.8 million recreational and athletic concussions occur annually in the United States, according to the Centers for Disease Control and Prevention.

7 Dec 2015

Medicine News and Research

CTTV launches new web platform for identifying therapeutic targets

Penile prostheses benefit men with erectile dysfunction

Macrophages play key role in maintaining healthy arteries after inflammation

NEK7 enzyme acts as on-off switch in innate immune system

First targeted treatment to improve survival of high-risk patients with acute myeloid leukemia

Researchers identify genes that act as brakes to stop development of aggressive type of leukaemia

Dompé’s investigational biotech molecule receives orphan drug designation for treatment of neurotrophic keratitis

Innovative DNA technology enables faster and more effective diagnosis of TB cases

Study: Certain characteristics can lead to therapy-related leukemia in breast cancer survivors

Takeda presents Phase 3 TOURMALINE-MM1 data for multiple myeloma at ASH 2015

Phase 1 BelCHOP study shows belinostat and CHOP chemo regimen as first-line treatment for PTCL

Motivational interviewing helps curb prescription opioid abuse among older adults with chronic pain

XARELTO reduces rates of major bleeding, recurrent blood clots in people with deep vein thrombosis

Hybrid Photon Counting (HPC) technology based on newest ASIC platform for X-ray imaging

New approaches to treating leukemia, lymphoma and myeloma

Yale researchers develop vaccine strategy that reduces risk of flu in cancer patients

Risk of dementia decreasing? An interview with Professor Carol Brayne, University of Cambridge

Age and body fat also contribute to breast cancer risk, say Johns Hopkins researchers

Cell Therapy Catapult’s 2015 Annual Review highlights key achievements across UK’s health and economy

Tips to help lower risk of sports-related concussions

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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