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Is non-severe SARS-CoV-2 infection characterized by early T cell proliferation?

To date, little evidence has been documented regarding the immune responses after the onset of the symptoms or virus detection. Further, no cross-sectional studies have been conducted that define the time of infection. Thereby, no report is available that explains the relationship between the earliest immune responses to COVID-19 and temporal kinetics. New research deals with this research gap using blood transcriptomics, multiparameter flow cytometry, and T cell receptor (TCR) sequencing methods.

6 Apr 2021

New RNA-sequencing method can help detect numerous modified small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method-- "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

5 Apr 2021

Deep learning algorithms improve diagnostic performance of breast ultrasound

Ultrasound is widely used to detect breast cancer early, but misdiagnosis of benign lesions as malignant tumors sometimes leads to unnecessary biopsies.

5 Apr 2021

FIND announces launch of a request for proposals to expand access to COVID-19 testing services

The Foundation for Innovative New Diagnostics (FIND) announced today the launch of a request for proposals (RFP) to accelerate the development, manufacturing, and market availability of accurate, affordable, quality-assured and easy-to-use SARS-CoV-2 self-tests for use in low- and middle-income countries (LMICs).

5 Apr 2021

Stay-at-home measures may have offered protective effects for youth mental health early in the pandemic

A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, reports that middle schoolers from a predominantly Latinx community, with elevated levels of mental health problems, showed a reduction in symptoms during the early stages of the pandemic.

3 Apr 2021

Study: More than 60% of adult e-cigarette users in the U.S want to quit

More than 60% of U.S. adults who vape are interested in quitting, according to a study published today in JAMA Network Open by MUSC Hollings Cancer Center researchers.

3 Apr 2021

Backed by millions in public and private cash, rapid Covid tests are coming to stores near you

Scientists and lawmakers agree that over-the-counter Covid tests could allow desk workers to settle back into their cubicles and make it easier to reopen schools and travel.

1 Apr 2021

FDA investigates contributing factors for reported infections from reprocessed urological endoscopes

Today, the U.S. Food and Drug Administration announced it is investigating numerous medical device reports (MDRs) describing patient infections and other possible contamination issues associated with reprocessing urological endoscopes, including cystoscopes, ureteroscopes and cystourethroscopes—devices used to view and access the urinary tract.

1 Apr 2021

Metabolic dysfunction found in mouse models of neurodevelopmental disorders

Mouse models of neurodevelopmental disorders possess unique, sex-specific metabolic dysfunctions, according to a new study in eNeuro.

1 Apr 2021

Temperature difference in the upper and lower respiratory tract influences SARS-CoV-2 replication

A team of researchers from the Institute for Infectious Diseases (IFIK) at the University of Bern and the Federal Institute of Virology and Immunology (IVI) have assessed virus growth and activation of the cellular defense mechanisms in the respiratory tract.

1 Apr 2021

CDC and NIH launch community COVID-19 testing initiative

The Centers for Disease Control and Prevention, in collaboration with the National Institutes of Health, has launched an innovative community health initiative called "Say Yes! COVID Test" starting in Pitt County, North Carolina, and coming soon to Chattanooga/Hamilton County Tennessee.

31 Mar 2021

Study looks at U.S. mammography screening rates during the COVID-19 pandemic

In looking at the broader impact of the COVID-19 pandemic on health and wellbeing, public health experts are examining screening rates for cancer.

31 Mar 2021

Study finds dramatic increases in rates of insomnia, sleep apnea among US military members

Insomnia and obstructive sleep apnea have increased dramatically among active-duty military members over a 14-year period, 2005 through 2019.

31 Mar 2021

Study of twins reveals differences in adaptive immunity towards SARS-CoV-2

Twins may look alike on the outside, but not so much on the inside. That's one takeaway from a new preprint study posted to the medRxiv server where Brazilian researchers observed different T-cell responses in two pairs of identical twins exposed to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One twin who was reinfected with SARS-CoV-2 four months after had low recognition of CD4+ and CD8+ T-cell epitopes.

31 Mar 2021

New tool could help children with medical complexities avoid long hospitalizations

Too often, contends UMass Lowell faculty researcher Brenna Morse, children with complex chronic medical conditions spend days in the hospital undergoing tests for what could be a simple diagnosis.

30 Mar 2021

FDA waiver broadens the use of chlamydia and gonorrhea test at more point-of-care settings

Today, the U.S. Food and Drug Administration announced it is allowing the use of the Binx Health IO CT/NG Assay at point-of-care settings, such as in physician offices, community-based clinics, urgent care settings, outpatient health care facilities and other patient care settings, operating under a CLIA Certificate of Waiver, Certificate of Compliance or Certificate of Accreditation.

30 Mar 2021

Researchers develop novel test that screens for SARS-CoV-2 variants of concern

A team of scientists from the United States has recently developed a single-tube duplex molecular assay for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants containing E484K and N501Y spike mutations.

30 Mar 2021

New diagnostic test can detect COVID-19 virus even when it mutates

A team of scientists led by Nanyang Technological University, Singapore (NTU Singapore) has developed a diagnostic test that can detect the virus that causes COVID-19 even after it has gone through mutations.

30 Mar 2021

New approach can help identify patients at risk for esophageal cancer

A combination of esophageal brushing and extensive genetic sequencing of the sample collected can detect chromosome alterations in people with Barrett's Esophagus, identifying patients at risk for progressing to esophageal cancer, according to a new study by researchers at the Johns Hopkins Kimmel Cancer Center and Case Western Reserve University.

29 Mar 2021

Simulation course increases physician confidence up to 125% while improving knowledge, cognitive and technical skills

The American Society for Reproductive Medicine (ASRM) publishes the first validation study on the ASRM Embryo Transfer Simulator, showing significant improvements in Embryo Transfer competence.

From VirtaMed 29 Mar 2021

Diagnostic News and Research

Is non-severe SARS-CoV-2 infection characterized by early T cell proliferation?

New RNA-sequencing method can help detect numerous modified small RNAs

Deep learning algorithms improve diagnostic performance of breast ultrasound

FIND announces launch of a request for proposals to expand access to COVID-19 testing services

Stay-at-home measures may have offered protective effects for youth mental health early in the pandemic

Study: More than 60% of adult e-cigarette users in the U.S want to quit

Backed by millions in public and private cash, rapid Covid tests are coming to stores near you

FDA investigates contributing factors for reported infections from reprocessed urological endoscopes

Metabolic dysfunction found in mouse models of neurodevelopmental disorders

Temperature difference in the upper and lower respiratory tract influences SARS-CoV-2 replication

CDC and NIH launch community COVID-19 testing initiative

Study looks at U.S. mammography screening rates during the COVID-19 pandemic

Study finds dramatic increases in rates of insomnia, sleep apnea among US military members

Study of twins reveals differences in adaptive immunity towards SARS-CoV-2

New tool could help children with medical complexities avoid long hospitalizations

FDA waiver broadens the use of chlamydia and gonorrhea test at more point-of-care settings

Researchers develop novel test that screens for SARS-CoV-2 variants of concern

New diagnostic test can detect COVID-19 virus even when it mutates

New approach can help identify patients at risk for esophageal cancer

Simulation course increases physician confidence up to 125% while improving knowledge, cognitive and technical skills

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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