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Testosterone cause of sex differences in the occurrence of Parkinson’s disease, new research suggests

Men are twice as likely as women to develop Parkinson's disease, a nervous system disorder characterized by tremors and difficulty moving. New research to be presented at Cardiovascular, Renal and Metabolic Diseases: Physiology and Gender suggests that the difference in risk may be due to the presence of the male sex hormone testosterone.

19 Nov 2015

New study identifies patient-reported barriers to quality end-of-life care among ethnic minorities

A new study identifies six main patient-reported barriers to receiving quality end-of-life (EOL) care among ethnic minority populations. The biggest barrier is lack of sufficient financial resources and insurance, according to the article published in Journal of Palliative Medicine, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

19 Nov 2015

New technique improves accuracy of CRISPR/Cas9 gene editing system

A new CRISPR/Cas9 technology developed by scientists at the University of Massachusetts Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.

19 Nov 2015

New insulin pill shows promise as novel form of therapy for diabetes

An insulin pill being developed by researchers at UC Santa Barbara may in the near future give another blood sugar management option to those who suffer from diabetes. The novel drug delivery technology may also apply to a wide spectrum of other therapies.

19 Nov 2015

Role of biomarkers in drug development and regulatory decision making

Biomarkers in Medicine, a leading MEDLINE-indexed journal, has published a special focus issue exploring the increasingly important role of biomarkers in both drug development and regulatory decision making.

19 Nov 2015

Scientists, chefs explore ways to help people with neurologically-related taste impairments enjoy food again

Two women, seated at a table, told their stories in quiet tones. A group of chefs, some standing, others seated, leaned forward eagerly, clearly interested in what these two women had to say. They peppered the women with questions: did food taste better cold or hot? Was texture an issue? Did a glass of wine before dinner help or hurt the flavor experience? The women have taken chemotherapy for their cancer. One of them -- Gina Mullin -- will be taking chemotherapy every three weeks for the rest of her life. Both of them tell heartbreaking stories about a side effect of chemotherapy that gets swept under the rug: food tastes terrible.

19 Nov 2015

IMB scientists unravel complex regulatory mechanism involved in brain development

Scientists at the Institute of Molecular Biology in Mainz have unraveled a complex regulatory mechanism that explains how a single gene can drive the formation of brain cells. The research, published in The EMBO Journal, is an important step towards a better understanding of how the brain develops. It also harbors potential for regenerative medicine.

19 Nov 2015

International task force aims to develop new approach to cancer prevention and treatment

Advancements in precision medicine have led to many new targeted cancer therapies for cancer patients. These treatments focus on using agents that target one or two genes that contribute to tumor development. The approach tends to be more effective against cancer cells and less toxic toward normal cells than standard chemotherapeutic regimens.

19 Nov 2015

Clinical study shows new Ebola vaccine stimulates strong immune responses in adults

A clinical trial of a new Ebola vaccine (ChAd3-EBO-Z) that resulted from an unprecedented global consortium assembled at the behest of the World Health Organization has found that it is well tolerated and stimulates strong immune responses in adults in Mali, West Africa and in the US, according to a study published in the latest issue of the journal Lancet Infectious Disease.

19 Nov 2015

New article examines women's perceptions of relationship in Fifty Shades of Grey

Examining women's perceptions of the relationship between Christian and Anastasia in the popular movie Fifty Shades of Grey is a safe and valuable way to discuss healthy and unhealthy relationship dynamics, including the warning signs of intimate partner violence. Young women expressed mixed views, describing parts of the movie relationship as exciting and romantic and other aspects as controlling, manipulative, and emotionally abusive in a new study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

19 Nov 2015

Potential treatment strategy for glycogen storage disease

Researchers from the Duke-NUS Graduate Medical School Singapore and Duke Medicine have identified a potential treatment strategy for an often-fatal inherited glycogen storage disease.

18 Nov 2015

Gamma interferon may have potential to prevent Ebola infection

The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on developing vaccines, but there is still a need for antiviral therapies to protect health care workers and local populations in the event of future outbreaks.

18 Nov 2015

Med Data Quest collaborates with WuXi AppTec to tackle oncology informatics challenges

Med Data Quest, a pioneering medical informatics total solution provider, today celebrates its successful collaboration with the Oncology Business Unit of the CRO giant WuXi AppTec, delivering the world's first mobile App OncoWuXi that was launched in October for customers to access WuXi oncology tumor models and capabilities more quickly and easily for cancer drug discovery and translational research.

18 Nov 2015

Duchenne muscular dystrophy could directly affect muscle stem cells

A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.

18 Nov 2015

Serum phosphorus levels can help predict risk of ESRD in African Americans with CKD

An increase in serum phosphorus levels in African Americans with chronic kidney disease (CKD) is associated with faster progression to kidney failure, known as end-stage renal disease (ESRD), according to new research presented at ASN Kidney Week 2015 November 3-8 in San Diego, CA. Previously confirmed in primarily Caucasian populations, the Indiana University School of Medicine study confirms serum phosphorus is linked to ESRD risk in African Americans.

18 Nov 2015

Exercise, healthy lifestyle habits may cut prostate cancer risk by up to 68%

A study that tracked tens of thousands of midlife and older men for more than 20 years has found that vigorous exercise and other healthy lifestyle habits may cut their chances of developing a lethal type of prostate cancer by up to 68 percent.

18 Nov 2015

Mount Sinai Roosevelt to be renamed as Mount Sinai West

The Mount Sinai Health System today announced that Mount Sinai Roosevelt will be renamed as Mount Sinai West. The hospital will continue to be the premier health care provider on the West Side of Manhattan, with all services continuing, the same insurances accepted and the same number of people employed.

18 Nov 2015

Scientists develop potent compound that promotes wakefulness, remedies sleep disorder narcolepsy

Hiroshi Nagase, a Professor at the International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, collaborated with Masashi Yanagisawa (Professor / Director of WPI-IIIS) and successfully developed a potent compound that promotes wakefulness and remedies the sleep disorder narcolepsy in model animals.

18 Nov 2015

URI researcher developing novel vaccine delivery system to improve nicotine vaccine effectiveness

Xinyuan Chen, an assistant professor of biomedical and pharmaceutical sciences, joined URI's College of Pharmacy after seven years at Massachusetts General Hospital in Boston, bringing with him a $1.08 million career development grant from the National Institute of Drug Abuse and a $432,000 grant from the National Institute of Allergy and Infectious Disease.

18 Nov 2015

Use of azithromycin early reduces risk of recurrent, severe LRTI among young children

Among young children with histories of recurrent severe lower respiratory tract illness (LRTI), the use of azithromycin early during an apparent RTI compared with placebo significantly reduced the risk of experiencing progression to severe LRTI, according to a study in the November 17 issue of JAMA.

18 Nov 2015

Medicine News and Research

Testosterone cause of sex differences in the occurrence of Parkinson’s disease, new research suggests

New study identifies patient-reported barriers to quality end-of-life care among ethnic minorities

New technique improves accuracy of CRISPR/Cas9 gene editing system

New insulin pill shows promise as novel form of therapy for diabetes

Role of biomarkers in drug development and regulatory decision making

Scientists, chefs explore ways to help people with neurologically-related taste impairments enjoy food again

IMB scientists unravel complex regulatory mechanism involved in brain development

International task force aims to develop new approach to cancer prevention and treatment

Clinical study shows new Ebola vaccine stimulates strong immune responses in adults

New article examines women's perceptions of relationship in Fifty Shades of Grey

Potential treatment strategy for glycogen storage disease

Gamma interferon may have potential to prevent Ebola infection

Med Data Quest collaborates with WuXi AppTec to tackle oncology informatics challenges

Duchenne muscular dystrophy could directly affect muscle stem cells

Serum phosphorus levels can help predict risk of ESRD in African Americans with CKD

Exercise, healthy lifestyle habits may cut prostate cancer risk by up to 68%

Mount Sinai Roosevelt to be renamed as Mount Sinai West

Scientists develop potent compound that promotes wakefulness, remedies sleep disorder narcolepsy

URI researcher developing novel vaccine delivery system to improve nicotine vaccine effectiveness

Use of azithromycin early reduces risk of recurrent, severe LRTI among young children

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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