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Unproven OS benefits from surrogate endpoint-based cancer drug approvals

The majority of cancer drugs recently approved by the US Food and Drug Administration on the basis of a surrogate endpoint either have an unknown effect on overall survival or have failed to show a survival benefit, say the authors of a research letter.

28 Oct 2015

IMBRUVICA (ibrutinib) wins Prix Galien USA 2015 Award in Best Pharmaceutical Agent category

Today, IMBRUVICA (ibrutinib) was awarded the prestigious Prix Galien USA 2015 Award in the category of Best Pharmaceutical Agent. The Prix Galien Award is considered to be the industry's highest accolade and recognizes the vital technical, scientific and clinical research skills necessary to develop medicines.

28 Oct 2015

Your job may be having effect on your waistline

Your job could be having an effect on your waistline, suggests new research published in Social Science & Medicine - and it could be bad or good news depending on the sort of control you have over your work.

28 Oct 2015

Conversational hypnosis may do better job than pills for relaxing patients before surgery

Anxious patients heading into surgery often receive medication to ease their fears, but a few calming words from their physicians might actually be more effective medicine. In fact, "conversational hypnosis" as the approach is known, may do a better job than pills for relaxing patients before anesthesia and surgery, suggests research being presented at the ANESTHESIOLOGY 2015 annual meeting.

28 Oct 2015

New studies analyse life expectancy, causes of death and child mortality in different regions of China

Two new studies, published in The Lancet, reveal for the first time how health in different regions of China has changed in recent decades.

28 Oct 2015

Study shows restoring testosterone production in men does not impact their fertility

Restoring testosterone production in men may be as effective as replacing it, without compromising their fertility. Two phase III clinical trials show that a drug that restores the body’s natural production of testosterone has no negative effect on a man’s sperm count while a topical testosterone gel causes a significant drop.

28 Oct 2015

New generation of incretin-based medicines allows coordinated action against diabesity

The new generation of incretin-based medicines will allow a coordinated action against the combination diabetes/obesity, also known as diabesity, in some cases with only a single weekly dose, and with the likelihood of additional beneficial effects on other health complications related to this condition, such as cardiovascular and neurodegenerative diseases.

28 Oct 2015

Study demonstrates efficacy of everolimus in treating nonfunctional neuroendocrine tumours of the lung

The results of the international, multicenter, Phase 3 RADIANT-4 study clearly demonstrate the efficacy of the agent everolimus in treating nonfunctional neuroendocrine tumours of lung or gastrointestinal origin.

28 Oct 2015

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor progression than cancer patients who did not receive the drug, according to results presented October 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego. This is the first study in humans to associate opioid blockade with improved survival.

28 Oct 2015

Study suggests potential new way to block cancer-causing gene

A new study suggests a potential new way to block one of the most common cancer-causing genes, without causing severe side effects.

28 Oct 2015

Study finds overall decreasing trend in leading causes of death

An analysis of deaths in the United States between 1969 and 2013 finds an overall decreasing trend in the age-standardized death rate for all causes combined and for heart disease, cancer, stroke, unintentional injuries, and diabetes, although the rate of decrease appears to have slowed for heart disease, stroke, and diabetes, according to a study in the October 27 issue of JAMA.

28 Oct 2015

New method to grow 3D pancreatic cancer organoid may help test drug responses and personalized treatments

The development of a new method to grow three-dimensional organoid cultures of pancreatic tumors directly from patients' surgical tissue offers a promising opportunity for testing targeted therapies and drug responses and personalizing treatments in a rapid, cost-effective manner.

28 Oct 2015

Risk of depression recurrence significantly lower for people with complete symptom resolution

People who have had an episode of major depression are at high risk for having another episode. Now, researchers at University of California, San Diego School of Medicine have found that the risk of recurrence is significantly lower for people with complete, rather than partial depressive symptom resolution.

28 Oct 2015

Watching too much TV increases risk of death

On average, 80% of American adults watch 3.5 hours of television per day and multiple observational studies have demonstrated a link between TV viewing and poorer health. In this new study published in the December issue of the American Journal of Preventive Medicine, investigators reported an association between increasing hours of television viewing per day and increasing risk of death from most of the major causes of death in the United States.

28 Oct 2015

Virginia Tech researchers study how specific cytokine influences gene expression patterns in T helper cells

Environment can make all the difference in behavior - even at the cellular level. Scientists at the Virginia Tech Carilion Research Institute have discovered even a small shift in environmental factors can change how a cell in the immune system matures.

28 Oct 2015

Lithium chloride could offer effective treatment against osteoarthritis

Bioengineers from Queen Mary University of London have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment against osteoarthritis by disrupting the length of the cells' antennae called primary cilia.

28 Oct 2015

Infections with Lone star ticks appear to be surging but deaths are not, new study reveals

A mild disease spread by the aggressive Lone star tick that is now colonizing large swaths of the United States is being mistaken for Rocky Mountain spotted fever, according to a new study from scientists at the U.S. Centers for Disease Control and Prevention.

28 Oct 2015

Pittcon will exhibit at the Bioconference clinical diagnostics and research virtual conference

Pittcon is pleased to announce its participation in the “Clinical Diagnostics & Research” virtual conference from November 11 to 12, 2015. Clinicians, researchers, medical experts, and professionals from around the world convene for this free web-conference to learn and interact with a community of like-minded colleagues.

From Pittcon 27 Oct 2015

MedStar Washington Hospital Center's Ebola Response Team recognized with 2015 Patient Safety Award

MedStar Washington Hospital Center's Ebola Response Team has been honored with the 2015 Patient Safety Award from the District of Columbia Hospital Association. The award recognizes the team's outstanding efforts in its Ebola-related plans and training to care for potential or confirmed patients with the Ebola virus.

27 Oct 2015

Insulin plays a much stronger role in regulating release of dopamine

Insulin, the hormone essential to all mammals for controlling blood sugar levels and a feeling of being full after eating, plays a much stronger role than previously known in regulating release of dopamine, a neurotransmitter that helps control the brain's reward and pleasure centers, new studies by researchers at NYU Langone Medical Center show.

27 Oct 2015

Medicine News and Research

Unproven OS benefits from surrogate endpoint-based cancer drug approvals

IMBRUVICA (ibrutinib) wins Prix Galien USA 2015 Award in Best Pharmaceutical Agent category

Your job may be having effect on your waistline

Conversational hypnosis may do better job than pills for relaxing patients before surgery

New studies analyse life expectancy, causes of death and child mortality in different regions of China

Study shows restoring testosterone production in men does not impact their fertility

New generation of incretin-based medicines allows coordinated action against diabesity

Study demonstrates efficacy of everolimus in treating nonfunctional neuroendocrine tumours of the lung

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Study suggests potential new way to block cancer-causing gene

Study finds overall decreasing trend in leading causes of death

New method to grow 3D pancreatic cancer organoid may help test drug responses and personalized treatments

Risk of depression recurrence significantly lower for people with complete symptom resolution

Watching too much TV increases risk of death

Virginia Tech researchers study how specific cytokine influences gene expression patterns in T helper cells

Lithium chloride could offer effective treatment against osteoarthritis

Infections with Lone star ticks appear to be surging but deaths are not, new study reveals

Pittcon will exhibit at the Bioconference clinical diagnostics and research virtual conference

MedStar Washington Hospital Center's Ebola Response Team recognized with 2015 Patient Safety Award

Insulin plays a much stronger role in regulating release of dopamine

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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