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VALIDATE Network’s TB vaccine work receives $1.5 million funding boost

The Oxford-run VALIDATE Network has received $1.5 million in funding for its tuberculosis vaccine work from the Bill & Melinda Gates Foundation.

23 Aug 2021

FDA-approved antiplatelet drug shows potential as new, low-cost heart failure therapy

Sarpogrelate, an antiplatelet medication, has potential as a new heart failure therapy and, according to researchers, could potentially decrease health care costs associated with cardiovascular disease, according to preliminary animal research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2021.

23 Aug 2021

ICL fluorescent label homogenously penetrates the glioblastoma brain tumors

Fluorescent indocarbocyanine lipid (ICL) shows much better distribution within glioblastoma brain tumors compared to fluorescent phospholipids, according to a study published in ACS Nano.

23 Aug 2021

Pecan-enriched diets can improve a person's cholesterol levels, study shows

While the proper pronunciation of pecan remains a subject of debate, University of Georgia researchers have shown the tree nut can dramatically improve a person's cholesterol levels.

23 Aug 2021

FDA approves COVID-19 mRNA vaccine that uses fundamental Penn technology

The U.S. Food and Drug Administration has given the first full approval to a COVID-19 mRNA vaccine, which uses modified mRNA technology invented and developed by scientists in the Perelman School of Medicine at the University of Pennsylvania, whose years of research in mRNA science laid a critical piece of the foundation for the largest global vaccination campaign in history.

23 Aug 2021

Study finds unacceptably alarming rise in gestational diabetes among U.S. women

The rate of gestational diabetes has shot up 30 percent in young U.S. women over the past decade and more than doubled in U.S. women who identify as Asian-Indian compared with non-Hispanic White women, reports a new Northwestern Medicine study published in JAMA.

23 Aug 2021

Drinking, smoking throughout the first trimester of pregnancy associated with higher stillbirth risk

Drinking alcohol and smoking tobacco cigarettes throughout the first trimester of pregnancy is associated with nearly three times the risk of late stillbirth (at 28 or more weeks), compared to women who neither drink or smoke during pregnancy or quit both before the end of the first trimester, according to a study funded by the National Institutes of Health.

23 Aug 2021

New study reveals unique immune responses to SARS-CoV-2, Ebola and respiratory syncytial virus using B cell repertoire analysis

A new study has been published on the bioRxiv* preprint server, which takes a long-read repertoire amplification approach to better understand, compare and contrast B cell responses to emerging or endemic viruses.

23 Aug 2021

Researchers identify eight primary factors that increase GI bleeding risk after heart attack

Researchers at Karolinska Institutet in Sweden have identified eight primary factors that increase the risk of a common bleeding complication after heart attack. Some of these factors are already known, but using machine learning techniques, the researchers have found additional predictors, such as smoking, blood pressure and blood glucose.

23 Aug 2021

Study uses computational modeling of coronavirus spike proteins to examine dynamics responsible for immunogenicity and immune escape

A new study published on the bioRxiv* preprint server focused on the development of dynamic computational models for a large subset of S proteins of SARS-CoV, MERS-CoV, and SARS-CoV-2.

23 Aug 2021

Exercise reduces severity of symptoms in patients with atrial fibrillation

A six-month exercise programme helps maintain normal heart rhythm and reduces the severity of symptoms in patients with atrial fibrillation, according to late breaking research presented at ESC Congress 2021.

23 Aug 2021

Drinking alcohol at a young age associated with accelerated arterial stiffening

Drinking alcohol during adolescence to young adulthood is associated with accelerated arterial stiffening, a precursor to cardiovascular disease. That's the finding of a study presented at ESC Congress 2021.

23 Aug 2021

Pandemic unveils growing suicide crisis for communities of color

Rafiah Maxie has been a licensed clinical social worker in the Chicago area for a decade. Throughout that time, she'd viewed suicide as a problem most prevalent among middle-aged white men.

23 Aug 2021

As temperatures rise, so do the health risks for California’s farmworkers

Leoncio Antonio Trejo Galdamez, 58, died in his son's arms on June 29 after spending the day laying irrigation pipes in California's Coachella Valley. News of his death reverberated through the largely Latino community near the Mexican and Arizona borders — another casualty in a dangerous business.

23 Aug 2021

Study finds significant increase in opioid-associated cardiac arrests

A nationwide US study has shown that the rate of opioid-related cardiac arrests has steeply risen and is now on par with the rate of cardiac arrest from other causes. The research is presented at ESC Congress 2021.

23 Aug 2021

Researchers use residues in wastewater to study illicit drug consumption

At the start of the COVID-19 pandemic, stay-at-home orders and other restrictions drastically affected how people lived and worked, resulting in social isolation and economic instability. Now, researchers show that some people turned to a variety of drugs for relief. Using wastewater analysis, the team identified a spike in consumption of easily abused prescription opioids and anti-anxiety sedatives, while some illicit drug use plummeted, between March and June 2020.

23 Aug 2021

Study investigates the effects of calycosin on breast cancer cell progression

Aging-US published "Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1" which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited proliferation, migration, and invasion by T47D and MCF-7 breast cancer cells by downregulating basic leucine zipper ATF-like transcription factor expression.

23 Aug 2021

Visual imagination motivates people to engage in pleasurable and achievement-oriented activities

People struggling to motivate themselves to engage in activities that are good for them should tap into their imagination to visualize themselves carrying out the activity, according to new research from The University of Western Australia.

23 Aug 2021

Masimo PVi may provide useful information for monitoring the volume status in spontaneously breathing hemodialysis patients

Masimo announced today the findings of a study published in the Turkish Journal of Emergency Medicine in which Drs. Seda Dağar and Hüseyin Uzunosmanoğlu at the Kecioren Training and Research Hospital in Ankara, Turkey investigated the role that noninvasive, continuous Masimo PVi® might play in monitoring volume status and volume changes in spontaneously breathing patients undergoing hemodialysis.

23 Aug 2021

Curia to expand U.S. commercial manufacturing capability

Curia, formerly AMRI, a leading contract research, development and manufacturing organization, today announced plans to expand its commercial manufacturing capacity at its Rensselaer, New York facility.

From Curia 23 Aug 2021

Research News and Research

VALIDATE Network’s TB vaccine work receives $1.5 million funding boost

FDA-approved antiplatelet drug shows potential as new, low-cost heart failure therapy

ICL fluorescent label homogenously penetrates the glioblastoma brain tumors

Pecan-enriched diets can improve a person's cholesterol levels, study shows

FDA approves COVID-19 mRNA vaccine that uses fundamental Penn technology

Study finds unacceptably alarming rise in gestational diabetes among U.S. women

Drinking, smoking throughout the first trimester of pregnancy associated with higher stillbirth risk

New study reveals unique immune responses to SARS-CoV-2, Ebola and respiratory syncytial virus using B cell repertoire analysis

Researchers identify eight primary factors that increase GI bleeding risk after heart attack

Study uses computational modeling of coronavirus spike proteins to examine dynamics responsible for immunogenicity and immune escape

Exercise reduces severity of symptoms in patients with atrial fibrillation

Drinking alcohol at a young age associated with accelerated arterial stiffening

Pandemic unveils growing suicide crisis for communities of color

As temperatures rise, so do the health risks for California’s farmworkers

Study finds significant increase in opioid-associated cardiac arrests

Researchers use residues in wastewater to study illicit drug consumption

Study investigates the effects of calycosin on breast cancer cell progression

Visual imagination motivates people to engage in pleasurable and achievement-oriented activities

Masimo PVi may provide useful information for monitoring the volume status in spontaneously breathing hemodialysis patients

Curia to expand U.S. commercial manufacturing capability

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