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Study: Women less likely than men to have good relief of chronic pain with long-term opioid use

Women, and especially younger women, are much less likely than men to have good relief of chronic, non-cancer pain with long-term opioid use, with only one in five women reporting low levels of pain and high levels of function with chronic opioid therapy in a new study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

9 Oct 2015

New national report on use of antiviral drugs to treat, prevent influenza

A major new national report into the use of antiviral drugs (neuraminidase inhibitors) to treat and prevent influenza has drawn heavily on two pieces of research undertaken at The University of Nottingham.

9 Oct 2015

FDA grants accelerated approval for Keytruda to treat patients with advanced NSCLC

The U.S. Food and Drug Administration today granted accelerated approval for Keytruda (pembrolizumab) to treat patients with advanced (metastatic) non-small cell lung cancer (NSCLC) whose disease has progressed after other treatments and with tumors that express a protein called PD-L1. Keytruda is approved for use with a companion diagnostic, the PD-L1 IHC 22C3 pharmDx test, the first test designed to detect PD-L1 expression in non-small cell lung tumors.

9 Oct 2015

Antioxidants can increase rate of melanoma metastasis in mice

Fresh research at Sahlgrenska Academy has found that antioxidants can double the rate of melanoma metastasis in mice. The results reinforce previous findings that antioxidants hasten the progression of lung cancer. According to Professor Martin Bergö, people with cancer or an elevated risk of developing the disease should avoid nutritional supplements that contain antioxidants.

9 Oct 2015

NanoString Technologies will donate to honor cancer survivors featured in its newest campaign

To honor six cancer survivors featured in its newest international ad campaign, NanoString Technologies, Inc. will donate $6,000 to the American Cancer Society. The “Dear Cancer Researcher” participants courageously shared their personal stories of triumph to help the biotechnology company launch its newest product, nCounter SPRINT™ Profiler, a system that gives researchers the tools and opportunity to think beyond current everyday practice.

From NanoString Technologies 9 Oct 2015

Daclizumab HYP superior to interferon in relapsing–remitting MS

The DECIDE study shows that 4-weekly daclizumab high-yield process reduces disease activity in patients with relapsing–remitting multiple sclerosis more effectively than weekly interferon beta-1a, albeit at the cost of more adverse effects.

8 Oct 2015

Celtaxsys commences acebilustat phase 2 trial in patients with cystic fibrosis in US

Celtaxsys, a clinical stage drug development company focused on advancing care for patients suffering from orphan inflammatory diseases, announced today the commencement of the US arm of an international phase 2 clinical trial for its flagship compound, acebilustat, in patients with cystic fibrosis (CF).

8 Oct 2015

SynAgile announces positive results from Phase 2a trial of continuous intraoral LD/CD therapy

SynAgile Corporation, a privately held pharmaceutical company that develops and commercializes drug delivery systems using its proprietary OraFuse intraoral technology platform, today announced positive results from a proof-of-concept, Phase 2a, open-label clinical trial of continuous intraoral administration of levodopa-carbidopa (LD/CD).

8 Oct 2015

Phase II psoriasis study shows efficacy of Boehringer Ingelheim's BI 655066 over ustekinumab

New results from a Phase II head-to-head psoriasis study showed superior efficacy of Boehringer Ingelheim's investigational biologic compound BI 655066, over ustekinumab. After nine months, 69 percent of patients with moderate-to-severe plaque psoriasis maintained clear or almost clear skin (PASI 90) with BI 655066 in the higher dose group compared to 30 percent of patients on ustekinumab.

8 Oct 2015

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Mallinckrodt plc, a leading specialty biopharmaceutical company, today announced that data from a pilot study for its H.P. Acthar Gel (repository corticotropin injection) will be presented at the American College of Rheumatology 2015 Annual Meeting to be held November 7-11 in San Francisco.

8 Oct 2015

Immune-molecule-based mop-up therapy reduces specific type of breast tumor in mice

Disabling a cancer-causing pathway and administering an immune-molecule-based mop-up therapy eradicated a specific type of breast tumor in mice, according to researchers in the Perelman School of Medicine at the University of Pennsylvania.

8 Oct 2015

Gut microbiome can play significant role in the body's response to gluten

Investigators interested in celiac disease, a chronic gastrointestinal disorder caused by an immunologic response to the ingestion of gluten, have wondered why only 2% to 5% of genetically susceptible individuals develop the disease.

8 Oct 2015

New approach helps create virtual models for treating abdominal aortic aneurysms

Virtual models can be created in the angiography room thanks to an approach developed by researchers at the University of Montreal Hospital Research Centre and the university's departments of radiology, radiation oncology, and nuclear medicine. The latest advances were presented by Dr. Gilles Soulez at the Cardiovascular and Interventional Radiology Society of Europe conference on September 27, 2015.

8 Oct 2015

Genentech becomes Founding Sponsor for OPT-UP clinical study in MS, says ACP

Accelerated Cure Project for Multiple Sclerosis (ACP) announced today that Genentech, Inc., a member of the Roche Group, has become a Founding Sponsor for the Optimizing Treatment - Understanding Progression (OPT-UP) clinical study in multiple sclerosis (MS).

8 Oct 2015

New study shows electronic tracking system helps lower blood transfusions and infection rates

An electronic system that monitors how physicians give blood to patients after an operation has enabled a 22-hospital system with thousands of doctors to significantly reduce the amount of blood transfusions patients receive, cutting costs by $2.5 million over two years and contributing to lower infection rates without harming patients, according to a study presented at the 2015 Clinical Congress of the American College of Surgeons.

8 Oct 2015

Penn study forms basis for new treatment approaches for Sezary syndrome

Sezary syndrome (SS), an aggressive leukemia of mature T cells, is more complicated at a molecular level than ever suspected, according to investigators from the Perelman School of Medicine at the University of Pennsylvania.

8 Oct 2015

Wake Forest Baptist Medical Center announces creation of Technology Development Program

Wake Forest Baptist Medical Center today announced the creation of a Technology Development Program, a $15 million program to develop the ideas, discoveries and inventions of the faculty and staff of the Medical Center into life science technologies having the potential to benefit patients in the community and worldwide.

8 Oct 2015

Limiting consumption of sugary drinks helps combat childhood and adolescent obesity

More than one-third of children in the United States ages 6 to 19 years old are overweight or obese. Over the past 30 years, the number of obese adolescents has more than quadrupled, which also has led to an increase in children diagnosed with diabetes. To combat this trend, Aneesh Tosh, M.D., adolescent medicine physician at University of Missouri Health Care and associate professor of clinical child health at the MU School of Medicine, recommends that sugary drinks be removed from adolescents' diets.

8 Oct 2015

NIBIB-supported bioengineers work to reduce platelet activation and clotting in patients with VADs

A team of NIBIB-supported bioengineers, aerospace scientists, and cardiovascular clinicians are improving the function of the thousands of life-saving ventricular assist devices (VADs) implanted in advanced heart failure patients each year.

8 Oct 2015

Cleaning patient rooms with combination of chemicals and UV light cuts transmission of superbugs

Healthcare facilities continue to battle drug-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA) that loiter on surfaces even after patient rooms have been cleaned and can cause new, sometimes-deadly infections.

8 Oct 2015

Medicine News and Research

Study: Women less likely than men to have good relief of chronic pain with long-term opioid use

New national report on use of antiviral drugs to treat, prevent influenza

FDA grants accelerated approval for Keytruda to treat patients with advanced NSCLC

Antioxidants can increase rate of melanoma metastasis in mice

NanoString Technologies will donate to honor cancer survivors featured in its newest campaign

Daclizumab HYP superior to interferon in relapsing–remitting MS

Celtaxsys commences acebilustat phase 2 trial in patients with cystic fibrosis in US

SynAgile announces positive results from Phase 2a trial of continuous intraoral LD/CD therapy

Phase II psoriasis study shows efficacy of Boehringer Ingelheim's BI 655066 over ustekinumab

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Immune-molecule-based mop-up therapy reduces specific type of breast tumor in mice

Gut microbiome can play significant role in the body's response to gluten

New approach helps create virtual models for treating abdominal aortic aneurysms

Genentech becomes Founding Sponsor for OPT-UP clinical study in MS, says ACP

New study shows electronic tracking system helps lower blood transfusions and infection rates

Penn study forms basis for new treatment approaches for Sezary syndrome

Wake Forest Baptist Medical Center announces creation of Technology Development Program

Limiting consumption of sugary drinks helps combat childhood and adolescent obesity

NIBIB-supported bioengineers work to reduce platelet activation and clotting in patients with VADs

Cleaning patient rooms with combination of chemicals and UV light cuts transmission of superbugs

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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