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New book suggests ways to reduce medical reversals

Medical reversal—when accepted medical interventions are abandoned because they are found to be ineffective—is the "most important problem in medicine today," according to the authors of a new book: Ending Medical Reversal.

8 Oct 2015

UCSD researchers develop new microbiome analysis platform

The human microbiome -- the total collection of bacteria, viruses and other microorganisms living in and on your body -- has been linked to a variety of health and disease states, including obesity, allergies, asthma, and a rapidly growing list of other conditions. But as researchers try to sort out the complex relationship between microbial populations and human health and use that information to diagnose or treat disease, they are generating a deluge of microbial sequence data that first needs to be organized and analyzed.

8 Oct 2015

CAMH study: More than half of workers with depression do not perceive a need for treatment

More than half of workers who reported symptoms of depression did not perceive a need for treatment, according to a study from the Centre for Addiction and Mental Health (CAMH) in Toronto.

8 Oct 2015

High levels of satiety hormone leptin contribute to cardiovascular disease in obese individuals

While high levels of the satiety hormone leptin don't help obese individuals lose weight, they do appear to directly contribute to their cardiovascular disease, researchers report.

8 Oct 2015

Head injury patients do not benefit from brain cooling therapy

Head injury patients do not benefit from a therapy that involves cooling their bodies to reduce brain swelling, research has found.

8 Oct 2015

Smoking cessation medication 46% effective in women

The most effective prescription drug used to quit smoking initially helps women more than men, according to a Yale School of Medicine study. The study, published Oct. 7 by the journal Nicotine and Tobacco Research, found that varenicline, marketed as Chantix, was more effective earlier in women, and equally effective in women and men after one year.

8 Oct 2015

Claritas Genomics announces launch of Claritas Clinical Exome, novel diagnostic test

Claritas Genomics, Inc., announced the launch of its Claritas Clinical Exome, at the Annual Meeting of the American Society of Human Genetics running 10/6 – 10/10 in Baltimore, MD. This novel diagnostic test is the first to exploit the strengths of multiple DNA sequencing platforms simultaneously to deliver confirmed results for a patient’s clinical whole exome within 4 weeks, compared to the industry standard of 12 weeks or more. Patients with rare disease typically seek a diagnosis for 8-12 years, receiving 3-5 separate tests at a high cost.

7 Oct 2015

Genocea announces positive data in Phase 2 trial evaluating GEN-003 for the treatment of genital herpes

Genocea Biosciences, Inc. (NASDAQ:GNCA), a biopharmaceutical company developing T cell-directed vaccines and immunotherapies, has announced positive results from a planned interim analysis of data collected six months after dosing from its ongoing Phase 2 dose optimization trial evaluating GEN-003 for the treatment of genital herpes. At its best performing dose of 60 µg per protein / 75 µg of Matrix-M2TM adjuvant, GEN-003 demonstrated a statistically significant 58 percent reduction from baseline in the viral shedding rate (p < 0.0001), the primary endpoint of the study.

7 Oct 2015

Myriad Genetics and Tufts Health Plan sign agreement to cover Prolaris® for members with localized prostate cancer

Myriad Genetics, Inc. (NASDAQ: MYGN) has announced that it has signed a three-year contract with Tufts Health Plan through which the plan will provide coverage of Prolaris® for members diagnosed with localized prostate cancer. Prolaris is the first and only biopsy test validated against prostate cancer specific mortality.

7 Oct 2015

Interim data from long-term extension Tecfidera® (dimethyl fumarate) study

Biogen (NASDAQ: BIIB) will, this week, present data at the 31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) in Barcelona, Spain, demonstrating the efficacy and safety of TECFIDERA® (dimethyl fumarate) across a broad range of people with relapsing-remitting multiple sclerosis (RRMS).

7 Oct 2015

Cell Therapy Catapult launches Cell History File

The Cell Therapy Catapult, the organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the availability of the Cell History File (CHF) template document. The Cell History File template has been developed in conjunction with the UK’s Medicines and Healthcare products Regulatory Agency (MHRA), the Human Tissue Authority (HTA) and other cell therapy developers and manufacturers from academia and industry.

7 Oct 2015

Researchers find way to make social media more effective for improving exercise habits in people

Can the Web make people more fit? It's a question hot on the minds of everyone from health insurers to gym owners to public health officials. Although millions of dollars a year are being spent designing promotional ads and social media campaigns, they clearly aren't working: more than 43 percent of Americans get insufficient levels of daily exercise, and nearly a third are obese.

7 Oct 2015

Brain metastases evolve ‘clinically actionable’ mutations

Brain metastatic disease shows branched evolution from the primary tumour, suggest preliminary findings from the largest massively parallel sequencing study of paired samples performed so far.

7 Oct 2015

Houston Methodist-led research team one step closer to developing technologies to fix broken bones

A collaborative research team led by scientists at Houston Methodist is one step closer to developing technologies that could help mend broken bones faster. The Department of Defense awarded close to $6 million to the Houston Methodist Research Institute for an initiative aimed at studying two new materials to repair complex fractures in long bones.

7 Oct 2015

Use of chest CT scans for hospital emergency-room patients with blunt trauma can be reduced: Study

Use of computed tomography (CT) scans of the chest for hospital emergency-room patients with blunt trauma could be reduced by more than one-third without compromising detection of major injury, concludes a new study led by a UC San Francisco physician.

7 Oct 2015

UT Southwestern's William P. Clements Jr. University Hospital receives UHC's Rising Star Quality Leadership award

UT Southwestern Medical Center's William P. Clements Jr. University Hospital has received a national Rising Star Quality Leadership award from the University HealthSystem Consortium for its quality and safety efforts.

7 Oct 2015

Penn Medicine announces $375,000 in new grants to support BRCA-focused research projects

Penn Medicine's Basser Center for BRCA announced $375,000 in new grant funding to support BRCA-focused research projects across the nation. The grants are aimed at advancing the care of patients living with BRCA1 and BRCA2 mutations.

7 Oct 2015

UC Davis researchers awarded $15.5 million to develop world's first total-body PET scanner

A UC Davis research team has been awarded $15.5 million to build the world's first total-body positron emission tomography (PET) scanner, which could fundamentally change the way cancers are tracked and treated and put the university on the nation's leading edge of molecular imaging.

7 Oct 2015

Innovative one-year project aims to bridge gap between healthcare education and clinical practice

Caring for patients in an acute care setting in a hospital requires a team approach and involves a multitude of healthcare professionals including nurses, attending physicians, residents, case managers, pharmacists, and clinical psychologists to name a few. Each of these professions enters into practice with different skills sets, knowledge and professional identities that contribute to patient care. Yet, in many circumstances, barriers exist between disciplines that can obstruct a team-based system.

7 Oct 2015

New guidance statement on palliative care to be presented at 2015 Palliative Care in Oncology Symposium

A new guidance statement from the American Society of Clinical Oncology and the American Academy of Hospice and Palliative Medicine is being presented for the first time at the 2015 Palliative Care in Oncology Symposium in Boston.

7 Oct 2015

Medicine News and Research

New book suggests ways to reduce medical reversals

UCSD researchers develop new microbiome analysis platform

CAMH study: More than half of workers with depression do not perceive a need for treatment

High levels of satiety hormone leptin contribute to cardiovascular disease in obese individuals

Head injury patients do not benefit from brain cooling therapy

Smoking cessation medication 46% effective in women

Claritas Genomics announces launch of Claritas Clinical Exome, novel diagnostic test

Genocea announces positive data in Phase 2 trial evaluating GEN-003 for the treatment of genital herpes

Myriad Genetics and Tufts Health Plan sign agreement to cover Prolaris® for members with localized prostate cancer

Interim data from long-term extension Tecfidera® (dimethyl fumarate) study

Cell Therapy Catapult launches Cell History File

Researchers find way to make social media more effective for improving exercise habits in people

Brain metastases evolve ‘clinically actionable’ mutations

Houston Methodist-led research team one step closer to developing technologies to fix broken bones

Use of chest CT scans for hospital emergency-room patients with blunt trauma can be reduced: Study

UT Southwestern's William P. Clements Jr. University Hospital receives UHC's Rising Star Quality Leadership award

Penn Medicine announces $375,000 in new grants to support BRCA-focused research projects

UC Davis researchers awarded $15.5 million to develop world's first total-body PET scanner

Innovative one-year project aims to bridge gap between healthcare education and clinical practice

New guidance statement on palliative care to be presented at 2015 Palliative Care in Oncology Symposium

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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