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Innovative nanofluidic device detects single proteins at their naturally high concentrations

In the evolving world of precision medicine, the need for methods that can measure biomolecules with supreme accuracy and specificity is paramount. Recognizing this, Associate Professor Yan Xu of the Graduate School of Engineering at Osaka Metropolitan University and his international research team have made a great stride in this direction. They have developed an innovative nanofluidic device capable of capturing single proteins stochastically and detecting them digitally at their naturally high concentrations. This breakthrough could potentially lay the foundation for the future of personalized disease prevention and treatment.

26 Jun 2023

Discovery of new biomarkers could lead to early detection of bladder cancer

A University of Houston biomedical engineer and his team are reporting the discovery of new biomarkers for early detection of bladder cancer (BC), among the most common cancers diagnosed in men in the U.S.

27 Apr 2023

Riboswitch may be the key to advance gene therapy, regenerative medicine

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

30 Mar 2023

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

Cedars-Sinai investigators found that women who developed mood and anxiety disorders associated with pregnancy and childbirth had specific altered proteins circulating in their bloodstream in the third trimester.

23 Feb 2023

Wearable technology could improve doctors' ability to administer precise medication doses

For some of the powerful drugs used to fight infection and cancer, there's only a small difference between a healing dose and a dose that's large enough to cause dangerous side effects.

7 Dec 2022

Aptamer Group opens new facilities to meet the increasing demand for Optimer technology

Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, announces that it has opened its new facilities in York Science Park, UK, that will enable it to meet the increasing demand for Optimer technology.

From Aptamer Group 30 Nov 2022

A novel molecularly imprinted polypyrrole electrode for diagnosing COVID-19

A recent study examines the interaction between the SARS-CoV-2 spike glycoprotein through the use of a molecularly imprinted polypyrrole electrode.

12 Oct 2022

Many diverse nanopore research directions and applications beyond DNA sequencing

In a recent Nature Nanotechnology study, researchers describe diverse applications of nanopore-based technology beyond deoxyribonucleic acid (DNA) sequencing. More specifically, the current research focuses on the advancements of this technology within chemistry, biophysics, and nanoscience.

29 Sep 2022

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Researchers developed a high-throughput, rapid antigen SARS-CoV-2 spike protein detection test using allonamers, a new type of aptamers that carry out allosteric regulation instead of catalytic activity.

28 Sep 2022

What is the efficacy of bioelectronic masks for the detection of respiratory infectious diseases like COVID-19?

In a new study, researchers demonstrated the detection of respiratory infectious diseases using bioelectronic masks.

21 Sep 2022

Highly sensitive mask can detect respiratory viruses in the air within 10 minutes

Scientists have created a face mask that can detect common respiratory viruses, including influenza and the coronavirus, in the air in droplets or aerosols.

19 Sep 2022

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

New anticoagulant platform holds promise as a revolutionary advancement over the current blood thinners

While blood clotting is important to prevent blood loss and for our immunity, coagulation also can cause health issues and even death. Currently, one in four people worldwide dies from diseases and conditions caused by blood clots.

15 Jul 2022

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

24 May 2022

Emerging DNA-based sensors are promising tools for food safety

In a recent study published in the journal TrAC Trends in Analytical Chemistry, researchers discussed the current trends, challenges, and future of the deoxyribonucleic acid (DNA)-based sensors in real-time and rapid food contaminants analysis.

18 May 2022

Researchers develop treatment that suppresses mutational escape of SARS-CoV-2

Researchers from Xiamen University have created a new treatment that is less likely to be affected by mutations in the receptor-binding domain of SARS-CoV-2.

17 May 2022

Deoxyribonucleic acid nanostructure sensor found to rapidly detect and inhibit SARS-CoV-2

Researchers reported on a three-layer designer deoxyribonucleic acid (DNA) nanostructure (DDN) strategy-based sensor designed by them for rapid and accurate SARS-CoV-2 detection and inhibition.

9 May 2022

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

In a recent article published in the journal Proceedings of the National Academy of Sciences (PNAS), researchers reviewed the present-day therapeutic landscape of coronavirus disease 2019 (COVID-19) and addressed future opportunities to overcome challenges that hinder drug development and improve the global preparedness for future pandemics.

10 Apr 2022

Researchers design RNA molecules for delivering therapies directly to beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 diabetes.

7 Apr 2022

Sustainable material-based biosensors for SARS-CoV-2 detection

Researchers conducted a brief review on biosensors based on sustainable materials for SARS-CoV-2 detection.

15 Mar 2022