Nuclear Magnetic Resonance (NMR) News and Research

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Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Dietary components that impact anti-tumor immunity.

28 Nov 2023

Is there a causal link between polyunsaturated fatty acids and osteoarthritis?

The causal effects of polyunsaturated fatty acids (PUFAs) on knee and hip osteoarthritis (OA).

17 Nov 2023

Avocado a day may keep diabetes at bay, suggests nutritional biomarker study

New research in The Journal of Nutrition links avocado consumption with lower diabetes risk, revealing specific metabolomic biomarkers that indicate potential for reduced fasting glucose and insulin levels.

5 Nov 2023

Novel GLP-1 receptor agonists offer hope for long-lasting diabetes treatment

In a study published in Scientific Reports, researchers engineer long-lasting GLP-1 receptor agonists by fusing GLP-1 with an HSA-binding protein. These chimeric molecules show promise for the treatment of type 2 diabetes due to their stability, functionality, and high affinity for the GLP-1 receptor and human serum albumin.

22 Oct 2023

New insights into coronavirus E channel could lead to antiviral drugs

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

13 Oct 2023

Low-molecular weight human interleukin-1β antagonist discovered

Researchers described the detection of a human interleukin-1β antagonist with low molecular weight that disrupts interactions with the interleukin-1 receptor type I receptor.

11 Sep 2023

Clovibactin - a game-changing novel antibiotic with no resistance

Researchers reported the discovery of a new antibiotic, clovibactin.

6 Sep 2023

Early life high fructose exposure is associated with increased prevalence of adolescent anxiety disorders

Researchers investigated whether exposure to high fructose in early life directly affects essential microglia function.

4 Sep 2023

Study suggests whole egg consumption has benefits over egg white consumption in young, healthy adults

Researchers investigated the impacts of different egg-based diets on healthy young individuals' immune, hematologic, and metabolic clinical profiles.

30 Aug 2023

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

This recent study identifies new urinary biomarkers for detecting acute COVID-19 using spectroscopic analysis. The findings reveal that these biomarkers could offer valuable tools for early diagnosis, understanding the severity of the disease, and possibly contribute to endogenous immunological defense mechanisms against SARS-CoV-2.

29 Aug 2023

New powerful antibiotic isolated from bacteria could combat multi-resistant 'superbugs'

A new powerful antibiotic, isolated from bacteria that could not be studied before, seems capable to combat harmful bacteria and even multi-resistant 'superbugs'.

22 Aug 2023

Study sheds light on how SARS-CoV-2 virus switches between replication and packaging

Immediately after the infection of a cell in the throat or lungs, the SARS-CoV-2 virus works very hard to replicate, using the human cell's metabolic pathways to produce its proteins and make sure that its genetic material (the RNA genome) is copied.

21 Aug 2023

Synergistic winter flounder antimicrobial peptides unveil new path to enhanced bactericidal therapy

The synergistic action of six winter flounder (WF) antimicrobial peptides (AMPs) against bacterial pathogens.

14 Aug 2023

Researchers convert β-Pinene into renewable feedstock for sustainable paracetamol and ibuprofen

Researchers have developed scalable processes to convert β-pinene into 4-IPEC, a feedstock for synthesizing sustainable versions of paracetamol and ibuprofen.

19 Jul 2023

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.

9 Jul 2023

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn.

23 Jun 2023

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens.

13 Jun 2023

Peptidomimetic antibiotics may be effective against resistant bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

1 Jun 2023

Arctic avengers: New microbial strains unleashed in the fight against plastic pollution

Researchers discover new microbial strains that can break down biodegradable plastic films.

31 May 2023

Swiss researchers identify plastic-degrading microbial strains in the Alps and Arctic region

Finding, cultivating, and bioengineering organisms that can digest plastic not only aids in the removal of pollution, but is now also big business.

13 May 2023