Perioperative News and Research

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Personalized prehabilitation reduces the risk of surgical complications

The weeks leading up to a major surgery can be a time of uncertainty and worry for patients, many of whom anticipate the need for rehabilition to get back on their feet.

12 Nov 2025

Intraoperative music therapy reduces anesthetic use and physiological stress

A groundbreaking study published in the peer-reviewed journal Music and Medicine demonstrates that intraoperative music therapy significantly reduces the amount of propofol and fentanyl required during laparoscopic cholecystectomy performed under general anesthesia.

27 Oct 2025

Study reveals the success of spinal anesthesia for preterm infants undergoing inguinal hernia surgery

Every year, more than 13 million babies are born prematurely worldwide, and up to one-third of them require surgical repair of inguinal hernias—a procedure that, under general anesthesia, carries significant postoperative risks such as apnea, bradycardia, and desaturation.

24 Oct 2025

Daytime sleepiness in older adults linked to cognitive decline after surgery

People 60 and older who are excessively sleepy during the day may have more problems with memory and thinking after surgery, suggests a study presented at the ANESTHESIOLOGY 2025 annual meeting.

13 Oct 2025

Study finds prolonged fasting common among infants before anesthesia

Most children - including nearly 80% of infants - go without clear liquids before surgery for at least twice as long as guidelines recommend, according to an analysis of data on more than 70,000 children presented at the ANESTHESIOLOGY 2025 annual meeting.

13 Oct 2025

Older non-English speakers face higher delirium risk after surgery

Older patients who primarily speak a language other than English may face a greater risk of developing delirium after surgery in U.S. hospitals, according to new research presented at the ANESTHESIOLOGY 2025 annual meeting. The

12 Oct 2025

Fentanyl-stimulant overdose deaths surge among older adults

Overdose deaths in adults age 65 and older from fentanyl mixed with stimulants, such as cocaine and methamphetamines, have surged 9,000% in the past eight years, matching rates found among younger adults, according to research presented at the ANESTHESIOLOGY 2025 annual meeting.

12 Oct 2025

Researchers identify a central controller of mitochondrial dynamics in disease

A key switch for cellular energy balance has been discovered in cells: it could potentially become the target of new therapies for diseases ranging from Parkinson's to rare disorders caused by defects in the cell's powerhouses, the mitochondria.

6 Oct 2025

Hippocrates study launches to address post-surgical health inequalities

A £2.8 million grant to combat health inequalities in patients having major surgery has been awarded to a team of clinicians and researchers at UCL and UCLH.

2 Oct 2025

Pediatric lung transplantation shows promising outcomes in China

Lung transplantation has transformed care for patients with end-stage respiratory failure, particularly among adults, where the number of procedures has grown dramatically over recent decades.

25 Sep 2025

Scientists outline how future therapies could change type 1 diabetes care

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

24 Sep 2025

Can high-protein supplements improve cancer recovery?

A systematic review shows high-protein oral nutritional supplements can lower complications and hospital stays in cancer patients, improving recovery outcomes.

16 Sep 2025

Combination immunotherapy prior to surgery shows encouraging results in mesothelioma

Results from an early phase clinical trial presented this week at the World Conference on Lung Cancer Meeting in Barcelona, Spain, and published in the Nature Medicine journal today [Monday, 8th September 2025] show that patients with mesothelioma - a rare cancer of the lining of the lung that may be caused by exposure to asbestos - who received a combination of two immunotherapy drugs, nivolumab and ipilimumab, before surgery had successful surgeries and encouraging early outcomes.

9 Sep 2025

New strategy for difficult-to-treat mesothelioma: Immunotherapy and ctDNA insights

People with operable diffuse pleural mesothelioma may benefit from immunotherapy before and after surgery, based on results of a clinical trial exploring the sequence of treatment and the role of surgery for this difficult to treat cancer.

8 Sep 2025

Adjuvant chemo-immunotherapy may benefit patients with resected stage IB–IIIA NSCLC, trial suggests

Interim results from the NADIM ADJUVANT Phase III trial, led by the Spanish Lung Cancer Group (GECP), suggest that adjuvant chemo-immunotherapy may reduce the risk of recurrence in patients with completely resected stage IB–IIIA non-small cell lung cancer (NSCLC) while maintaining an acceptable safety profile.

8 Sep 2025

Frailty and microbial imbalance drive GI complications in bladder cancer surgery

Gastrointestinal (GI) complications, such as postoperative ileus (POI) and intra-abdominal infections (IAI), remain a major concern after radical cystectomy for bladder cancer.

8 Sep 2025

Overweight status may offer survival benefits after major surgery in older adults

Older adults who are overweight may face a lower risk of death in the first 30 days following major elective surgery compared with those who have a normal body mass index (BMI), new research suggests.

26 Aug 2025

Study supports pre-surgery use of GLP-1 RAs for weight reduction

Overweight patients waiting for operations could safely use a particular type of weight-loss treatment to reduce the risk of surgical complications linked to their obesity, a new study reveals.

12 Aug 2025

Lavender oil could speed recovery after brain surgery

Lavender essential oil aromatherapy improves sleep quality and reduces postoperative delirium in brain surgery patients, offering a natural aid for recovery.

12 Aug 2025

Alcohol withdrawal syndrome increases risks and costs after major surgery

Patients who develop alcohol withdrawal syndrome (AWS) after major surgery face significantly higher risks of complications, longer hospital stays, and increased health care costs, according to a study published in the Journal of the American College of Surgeons (JACS).

28 Jul 2025