Stent News and Research

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A stent is a small mesh tube that’s used to treat narrowed or weakened arteries in the body.

You may have a stent placed in an artery as part of a procedure called angioplasty (AN-jee-oh-plas-tee). Angioplasty can restore blood flow through narrowed or blocked arteries. Stents help prevent arteries from becoming narrowed or blocked again in the months or years after treatment with angioplasty. You may also have a stent placed in a weakened artery to improve blood flow and to help prevent the artery from bursting.

Stents are usually made of metal mesh, but sometimes they’re made of fabric. Fabric stents, also called stent grafts, are used in larger arteries. Some stents are coated with medicines that are slowly and continuously released into the artery. These medicines help prevent the artery from becoming blocked again.

Landmark trial shows drug-eluting balloon as effective option for in-stent restenosis

Results from the first randomized clinical trial in the United States to compare a sirolimus-eluting balloon (DEB) to control group consisting of drug-eluting stent (DES) and balloon angioplasty (BA) for the treatment of bare-metal and DES in-stent restenosis (ISR) deemed DEB to be noninferior to conventional therapies.

28 Oct 2025

Cutting balloon angioplasty proves noninferior to intravascular lithotripsy in treating calcified coronary lesions

Results from the first randomized controlled trial to directly compare the safety and efficacy of cutting balloon (CB) angioplasty to intravascular lithotripsy (IVL) prior to drug-eluting stent (DES) implantation for the treatment of calcified coronary artery disease found CB to be noninferior to IVL.

28 Oct 2025

Sirolimus-eluting balloon strategy matches drug-eluting stents in large international PCI trial

New study results from a large international all-comer population of percutaneous coronary intervention (PCI) candidates found that utilizing a strategy of sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine drug-eluting stent (DES) implantation as part of the treatment for de novo coronary artery disease.

27 Oct 2025

Psychological distress after a heart attack emerges as a critical risk factor for heart health

Many people experience one or more types of psychological distress, including depression, anxiety, psychosocial stress or post-traumatic stress disorder (PTSD), after a heart attack, which can affect their physical recovery and long-term heart health, according to a new American Heart Association scientific statement, published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

22 Sep 2025

Heart attacks in women under age 65 are caused by factors other than clogged arteries

A new Mayo Clinic study finds that many heart attacks in people under 65 - especially women - are caused by factors other than clogged arteries, challenging long-standing assumptions about how heart attacks occur in younger populations.

15 Sep 2025

No advantage found in modulating antiplatelet therapy intensity after complex stenting

There was no benefit to modulating the intensity of antiplatelet therapy compared with standard antiplatelet therapy in high-risk patients who had undergone complex stenting procedures, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

4 Sep 2025

Trial compares the use of blood thinners after stenting in patients with acute coronary syndromes

Noninferiority was not demonstrated for death and ischemic events between P2Y12 inhibitor monotherapy and dual antiplatelet therapy (DAPT) given for 12 months after stenting in patients with acute coronary syndromes (ACS), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

3 Sep 2025

Intravenous cangrelor provides rapid platelet inhibition in cardiogenic shock

Compared with crushed ticagrelor, intravenous cangrelor provided immediate, effective platelet inhibition, with no increase in major bleeding and lower mortality rates in patients with acute myocardial infarction and cardiogenic shock, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Early aspirin discontinuation safe after complete revascularization in acute MI

Among low-risk patients with acute MI who underwent early complete revascularization and received one month of dual antiplatelet therapy (DAPT), P2Y12 inhibitor monotherapy was noninferior to continued DAPT for adverse cardiovascular and cerebrovascular events, while reducing bleeding risk.

3 Sep 2025

AI scans arteries and predicts risk after heart attack better than traditional review

Researchers found that AI applied to OCT imaging can standardize detection of thin-cap fibroatheroma (TCFA) and identify post–heart attack patients at higher two-year risk. Whole-segment AI analysis outperformed lesion-focused human review, offering stronger prognostic value and reassurance for low-risk patients.

2 Sep 2025

Miniature camera and AI reveal hidden dangers inside the coronary arteries

Measurements with a miniature camera inside the coronary arteries can accurately predict whether someone will suffer a recurrent heart attack.

1 Sep 2025

Adding aspirin raises cardiovascular events in high-risk CCS patients on anticoagulants

Adding aspirin increased the risk of cardiovascular events, death and major bleeding in high-risk patients with chronic coronary syndrome (CCS) who had prior stenting and were receiving long-term chronic oral anticoagulation (OAC), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1 Sep 2025

Research finds no added benefit from routine CT imaging after left main coronary intervention

Routine coronary computed tomography (CCT)-based follow-up after percutaneous coronary intervention (PCI) of the left main coronary artery did not reduce death, myocardial infarction (MI), unstable angina or stent thrombosis compared with symptom-based follow-up, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Exercise-based cardiac rehab benefits atrial fibrillation

Exercise-based cardiac rehabilitation lessens the severity, frequency, and recurrence of the most common form of irregular heart rhythm, atrial fibrillation, or AF for short, finds a pooled data analysis of the available research, published online in the British Journal of Sports Medicine.

30 Jul 2025

Brain-computer interfaces signal a new era in neurosurgery and neurorehabilitation

Brain-computer interface (BCI) technology is opening an unprecedented chapter in human-machine integration by establishing direct communication between the brain and external devices.

10 Jun 2025

P2Y12 inhibitors linked to lower rates of cardiovascular events compared to aspirin

Giving a P2Y12 inhibitor anti-clotting drug to patients with coronary artery disease is associated with lower rates of cardiovascular death, heart attack and stroke compared with traditional aspirin, with no increased risk of major bleeding, finds a study published by The BMJ today.

5 Jun 2025

Stenting improves long term outcomes in CTO PCI patients

In patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI), stenting demonstrated improved long-term survival and fewer cardiac arrests at one year.

2 May 2025

AI-based imaging performs equally well as ultrasound in guiding heart procedures

Patients with narrowing of at least 50% in three major coronary arteries did equally well when treated with a minimally invasive stent placement guided either by ultrasound-based imaging or by a novel, artificial-intelligence-powered (AI), non-invasive imaging technique derived from angiography, researchers reported at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

In sharp contrast to earlier studies, patients with severe triple-vessel heart disease fared equally well whether they underwent open-heart bypass surgery (CABG) or a less invasive procedure called PCI (percutaneous coronary intervention) at five years of follow-up, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Bentracimab reverses ticagrelor's antiplatelet effects during surgery and bleeding events

A drug developed as an antidote to the antiplatelet agent ticagrelor safely and effectively reversed ticagrelor's antiplatelet effects in patients undergoing urgent surgery or experiencing major bleeding, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

29 Mar 2025

Stent News and Research

Further Reading

Landmark trial shows drug-eluting balloon as effective option for in-stent restenosis

Cutting balloon angioplasty proves noninferior to intravascular lithotripsy in treating calcified coronary lesions

Sirolimus-eluting balloon strategy matches drug-eluting stents in large international PCI trial

Psychological distress after a heart attack emerges as a critical risk factor for heart health

Heart attacks in women under age 65 are caused by factors other than clogged arteries

No advantage found in modulating antiplatelet therapy intensity after complex stenting

Trial compares the use of blood thinners after stenting in patients with acute coronary syndromes

Intravenous cangrelor provides rapid platelet inhibition in cardiogenic shock

Early aspirin discontinuation safe after complete revascularization in acute MI

AI scans arteries and predicts risk after heart attack better than traditional review

Miniature camera and AI reveal hidden dangers inside the coronary arteries

Adding aspirin raises cardiovascular events in high-risk CCS patients on anticoagulants

Research finds no added benefit from routine CT imaging after left main coronary intervention

Exercise-based cardiac rehab benefits atrial fibrillation

Brain-computer interfaces signal a new era in neurosurgery and neurorehabilitation

P2Y12 inhibitors linked to lower rates of cardiovascular events compared to aspirin

Stenting improves long term outcomes in CTO PCI patients

AI-based imaging performs equally well as ultrasound in guiding heart procedures

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

Bentracimab reverses ticagrelor's antiplatelet effects during surgery and bleeding events

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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