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Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Many public health warnings have been issued against alcohol consumption, even in small quantities, though the evidence for such strict limits is controversial. The current study, published in the MDPI journal Nutrients, is a narrative review focused on clearing up some of the confusion associated with alcoholic drinks.

4 Jan 2023

Why do some people develop persistent lung sequelae after severe COVID-19?

Clinical presentation following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from mild self-limiting illness to severe respiratory failure. Many studies have analyzed the early acute phases of coronavirus disease 2019(COVID-19), but few focused on the longer-term sequelae following infection.

2 Jan 2023

Using the gut microbiome to understand and treat respiratory diseases

Researchers review the role of the gut microbiome in certain respiratory diseases.

22 Dec 2022

Review on nanoparticles usage for treating thrombosis induced by SARS-CoV-2 infections

Researchers provided an overview of nanomedicine strategies to treat coronavirus disease 2019 (COVID-19)-induced thrombosis.

21 Dec 2022

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Myocardial infarction is an ischemic disease in which a coronary artery supplying blood to the heart muscle is stenotic or obstructed, resulting in cardiac tissue necrosis.

16 Dec 2022

Correlating circulating adipokine levels with COVID-19 severity

Researchers determine whether plasma adipokine levels were associated with COVID-19-related systemic inflammation and severity.

14 Dec 2022

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

In a recent study posted to bioRxiv*, researchers in the United States assessed the impact of metabolic diseases on coronavirus disease 2019 (COVID-19) vaccine immunogenicity in a mouse model.

13 Dec 2022

Study suggests persistent inflammatory response triggered by SARS-CoV-2 may be responsible for observed sequelae in PASC patients

Researchers assessed the association of enhanced migratory or activated CD8+ T cell and reduced avidity reactive cellular response due to post-acute COVID-19 syndrome (PASC).

13 Dec 2022

Severe COVID-19 causes aging-like changes in the human brain

Severe COVID-19 triggers aging-like changes in the brain's frontal cortex region that results in cognitive deficits.

11 Dec 2022

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma.

9 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Researchers investigated the immunological mechanisms behind the decreasing efficacy of COVID-19 vaccines by evaluating the durability and magnitude of neutralizing antibodies and memory B and T cell responses to booster doses of mRNA COVID-19 vaccine.

8 Dec 2022

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.

5 Dec 2022

Detection of filoviruses by the innate immune system

In a new study, researchers examined how the innate immune system detects filoviruses.

1 Dec 2022

Study on mpox epidemiology in New York during summer 2022

Researchers presented a summary of their experience of identifying, managing, and vaccinating monkeypox (MPX) virus (MPXV)-infected individuals in New York during the summer season of 2022.

30 Nov 2022

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Researchers investigated whether severe COVID-19 patients exhibited inflammation and immune activation three months after hospitalization and explored the associations among COVID-19 severity, long COVID, and immune activation.

30 Nov 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Powerful imaging tool creates 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions

Gross anatomy reveals three-dimensional shapes of pathology at a large scale. Histology, in contrast, reveals the microscopic anatomy of biological structures. But that magnification comes at a cost - histology shows only two-dimensional shapes because it studies small, flat slices of stained tissue.

29 Nov 2022

Pediatric acute myeloid leukemia genetic subtypes with poor outcomes show increased inflammatory cytokine signaling

Researchers used ribonucleic acid (RNA) sequence data to understand the association between inflammatory cytokines and poor outcomes of pediatric Acute Myeloid Leukemia (pAML).

29 Nov 2022

Glycan signatures in rheumatic diseases and their associated functional implications

A new paper examines the understanding of glycosylation in an array of rheumatic diseases and indicates the potential for therapeutic interventions using the same mechanism.

28 Nov 2022

Necrosis News and Research

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Why do some people develop persistent lung sequelae after severe COVID-19?

Using the gut microbiome to understand and treat respiratory diseases

Review on nanoparticles usage for treating thrombosis induced by SARS-CoV-2 infections

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Correlating circulating adipokine levels with COVID-19 severity

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

Study suggests persistent inflammatory response triggered by SARS-CoV-2 may be responsible for observed sequelae in PASC patients

Severe COVID-19 causes aging-like changes in the human brain

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Detection of filoviruses by the innate immune system

Study on mpox epidemiology in New York during summer 2022

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Powerful imaging tool creates 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions

Pediatric acute myeloid leukemia genetic subtypes with poor outcomes show increased inflammatory cytokine signaling

Glycan signatures in rheumatic diseases and their associated functional implications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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