Neurodegeneration News and Research

RSS

Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Protein biomarkers in spinal fluid offer promise for early progressive supranuclear palsy diagnosis

Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed.

3 Jul 2024

New insights into brain energy metabolism may lead to neurodegenerative disease therapies

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

3 Jul 2024

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and Inflammation, share key messages from their paper "Sex-Dependent APOE4 Neutrophil-Microglia Interactions Drive Cognitive Impairment in Alzheimer's Disease" published in Nature Medicine.

3 Jul 2024

Study reveals refined carbs heighten inflammation and cardiovascular risk

A study in Nutrients journal finds that both the quantity and quality of carbohydrates impact inflammation and cardiovascular disease (CVD) risk. Higher refined carbohydrate intake is linked to greater inflammation and CVD, emphasizing the need for personalized dietary recommendations.

2 Jul 2024

Study finds promising new target for the treatment of Alzheimer's disease

A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led by researchers at Penn State.

2 Jul 2024

Lifestyle habits linked to faster cognitive decline in new study

A study in Nature Communications links specific lifestyle factors, such as smoking, alcohol consumption, and social contact, to the rate of cognitive decline in European adults.

1 Jul 2024

Penn researchers aim to uncover the underlying biological mechanisms of TBI-related neurodegeneration

A team of researchers led by Penn Medicine will investigate the link between traumatic brain injuries (TBI) and Alzheimer's disease and related dementias (ADRD) over the next five years with a $10 million grant from the National Institute of Neurological Disorders and Stroke (NINDS).

28 Jun 2024

CHARMs: A new hope for prion disease therapy

Drug development is typically slow: the pipeline from basic research discoveries that provide the basis for a new drug to clinical trials to production of a widely available medicine can take decades.

27 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

New link between sulfur metabolites in gut microbiome and neurodegenerative diseases revealed

Neurodegenerative diseases (NDDs), which have no known cures and elusive causes, result in irreversible damage to the brain and nervous system.

16 Jun 2024

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

A recent review outlines the necessary factors for widespread implementation and interpretation of Alzheimer's disease blood-based biomarkers (BBMs) at the population level, emphasizing the potential for early detection and improved diagnosis.

14 Jun 2024

Ashwagandha boosts memory and mood in clinical trial

A clinical trial found that acute and 30-day Ashwagandha supplementation improves cognitive function and mood markers, showing significant benefits in memory, attention, and well-being without adverse effects.

10 Jun 2024

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

Ketones show promise in preventing cognitive decline and neurodegeneration

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester have identified mechanisms in the brain's hippocampal network that are rescued by ketones.

31 May 2024

Memory decline reported by patients and partners may signal early Alzheimer's changes

A new study adds further evidence that when a patient or family member notices signs of persistent memory loss, it's important to speak with a doctor.

30 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Neurodegeneration News and Research

Further Reading

Protein biomarkers in spinal fluid offer promise for early progressive supranuclear palsy diagnosis

New insights into brain energy metabolism may lead to neurodegenerative disease therapies

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Study reveals refined carbs heighten inflammation and cardiovascular risk

Study finds promising new target for the treatment of Alzheimer's disease

Lifestyle habits linked to faster cognitive decline in new study

Penn researchers aim to uncover the underlying biological mechanisms of TBI-related neurodegeneration

CHARMs: A new hope for prion disease therapy

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

New link between sulfur metabolites in gut microbiome and neurodegenerative diseases revealed

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

Ashwagandha boosts memory and mood in clinical trial

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Ketones show promise in preventing cognitive decline and neurodegeneration

Memory decline reported by patients and partners may signal early Alzheimer's changes

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Breakthrough study reveals molecular drivers of Alzheimer's progression

PhoreMost introduces GlueSEEKER platform for discovery of molecular glue degraders

Genes and age reveal new insights into cognitive variability, study finds

Genetic link identified between inflammatory bowel disease and Parkinson's disease

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News