Research News and Research

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Experimental drug combination extends survival in mice with lung cancer, study finds

A combination of experimental drugs increased the attack of immune cells on non-small cell lung cancer (NSCLC) to extend survival in mice, a new study found.

5 Aug 2021

Mutation in a single gene may be responsible for non-obstructive azoospermia in men

Mutation in a single gene appears to account for a form of male infertility in which men fail to produce sperm, according to an international study funded in part by the National Institutes of Health.

5 Aug 2021

UAB researchers identify potential therapeutic target for ovarian cancer

A gene called DOT1L appears to play a role in progression and severity of ovarian cancer, and inhibitors of the DOT1L enzyme may offer a new therapeutic approach for the disease, University of Alabama at Birmingham researchers say in a study published in the journal Oncogenesis.

5 Aug 2021

Mobile interventional stroke team travels to patients for providing faster access to surgical treatment

Stroke patients were almost twice as likely to be functionally independent - mobile and able to perform daily tasks - at 90 days post-stroke if they were treated by a specialized mobile stroke team that traveled to them to perform mechanical clot removal, compared to those who were transferred to a thrombectomy stroke center, according to research conducted within the Mount Sinai Health System and published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.

5 Aug 2021

Researchers use AI to assess metastatic potential of melanoma cells

Using artificial intelligence (AI), researchers from UT Southwestern have developed a way to accurately predict which skin cancers are highly metastatic.

5 Aug 2021

Postpartum sleep deprivation associated with accelerated biological aging

When new mothers complain that all those sleepless nights caring for their newborns are taking years off their life, they just might be right, UCLA research published this summer in the journal Sleep Health suggests.

5 Aug 2021

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Frequent, rapid testing for COVID-19 is critical to controlling the spread of outbreaks, especially as new, more transmissible variants emerge.

5 Aug 2021

New DNA writing technique can precisely and efficiently edit bacterial genomes

Biological engineers at MIT have devised a new way to efficiently edit bacterial genomes and program memories into bacterial cells by rewriting their DNA.

5 Aug 2021

Low glycemic diet results in important improvements for people with diabetes

For people with diabetes, sticking to a low glycemic diet results in small but important improvements in blood sugar levels, cholesterol, weight and other risk factors, finds a study published by The BMJ today.

5 Aug 2021

Poor motor function from around age 65 associated with increased mortality risk

Increasing poor physical (motor) function from around age 65 is associated with an increased risk of death, finds research published by The BMJ today.

5 Aug 2021

KHN’s ‘What the Health?’: Delta blues

The U.S. is experiencing another surge of covid-19, particularly in Southern states where vaccination rates are generally lower than in other regions. But partisan fights rage on over what role government should play in trying to tamp down the highly contagious delta variant.

5 Aug 2021

CHEST releases new clinical guidelines for management of venous thromboembolism

The American College of Chest Physicians recently released new clinical guidelines for venous thromboembolism management, "Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel," that provides 29 recommendations on 17 Patients, Interventions, Comparators, Outcomes (PICO) questions, four of which have not been addressed previously.

5 Aug 2021

E-cigarette use during pregnancy poses health risk for offspring all the way into adulthood

The use of e-cigarettes (vaping) during pregnancy poses a significant health risk for the offspring, impairing blood vessel function even into adulthood, according to a new study by researchers at West Virginia University's School of Medicine.

5 Aug 2021

Research reveals undertreatment of headaches in racial and socioeconomic groups

Significant disparities exist in diagnosing and treating headaches by race, socioeconomic level, and insurance status, despite the fact that headaches afflict nearly all racial and ethnic groups at the same rate, according to research led by UT Southwestern Medical Center faculty.

5 Aug 2021

Research explores how cancer cells develop resistance to chemotherapy

Cancer cells sometimes develop resistance to the cytotoxic drugs used in chemotherapy. Figuring out why the treatment isn't working and why it may even defeat its own purpose is therefore important to understand.

5 Aug 2021

A correlation study between time-from-vaccine and SARS-CoV-2 breakthrough infections

A new retrospective study compares the incidence rates of breakthrough infections between different time points at which individuals were vaccinated.

5 Aug 2021

Vaccinia-based COVID-19 vaccines confer immunity in hamster model

In a paper recently uploaded to the preprint server bioRxiv* by Kulkarni et al. (August 3, 2021), the potential of vaccinia virus-based vaccines expressing the full-length SARS-CoV-2 spike protein is examined in mice and Syrian hamsters. The findings report that the vaccine generates high titers of neutralizing antibodies with good activity towards SARS-CoV-2 variants of concern.

5 Aug 2021

New study examines B cell receptor repertoires in COVID-19 patients

In a paper recently uploaded to the preprint server bioRxiv* by Kim et al. (August 2, 2021), the B cell receptor repertoire of 1,060 COVID-19 patients is compared to that of an equal number of healthy volunteers in a novel manner, utilizing computational deep-learning-based protein embedding techniques, which demonstrate a resolution capable of tracking the changes in immunity in an individual over the course of infection.

5 Aug 2021

Neural network model unravels why people with autism have difficulty interpreting facial expressions

People with autism spectrum disorder have difficulty interpreting facial expressions.

5 Aug 2021

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Modified mRNA combined with lipid nanoparticles may be beneficial in boosting adaptive immunity against SARS-CoV-2. Research led by Botond Z. Igyártó from Thomas Jefferson University’s Department of Microbiology and Immunology in Pennsylvania recently found that the lipid nanoparticles induce protective adaptive immune responses with antibody titers against lethal doses of the virus.

5 Aug 2021

Research News and Research

Experimental drug combination extends survival in mice with lung cancer, study finds

Mutation in a single gene may be responsible for non-obstructive azoospermia in men

UAB researchers identify potential therapeutic target for ovarian cancer

Mobile interventional stroke team travels to patients for providing faster access to surgical treatment

Researchers use AI to assess metastatic potential of melanoma cells

Postpartum sleep deprivation associated with accelerated biological aging

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

New DNA writing technique can precisely and efficiently edit bacterial genomes

Low glycemic diet results in important improvements for people with diabetes

Poor motor function from around age 65 associated with increased mortality risk

KHN’s ‘What the Health?’: Delta blues

CHEST releases new clinical guidelines for management of venous thromboembolism

E-cigarette use during pregnancy poses health risk for offspring all the way into adulthood

Research reveals undertreatment of headaches in racial and socioeconomic groups

Research explores how cancer cells develop resistance to chemotherapy

A correlation study between time-from-vaccine and SARS-CoV-2 breakthrough infections

Vaccinia-based COVID-19 vaccines confer immunity in hamster model

New study examines B cell receptor repertoires in COVID-19 patients

Neural network model unravels why people with autism have difficulty interpreting facial expressions

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

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