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Benznidazole has significant antiparasitic activity, but does not reduce progression of Chagas cardiomyopathy

A 40 to 80 day treatment with the antiparasitic medication benznidazole significantly reduced parasite activity in the blood, but not progression, of serious heart problems over a 5-year period among patients with established Chagas disease (CD) cardiomyopathy, results of the BENEFIT trial show.

1 Sep 2015

Abbott reports positive results of ABSORB Japan study comparing efficacy of fully dissolving heart stent to XIENCE

Abbott (NYSE: ABT) announced today positive one-year clinical results from ABSORB Japan, a multi-center, randomized trial comparing the safety and effectiveness of Abbott's fully dissolving Absorb™ heart stent to XIENCE ®, Abbott's market-leading, permanent drug eluting stent.

1 Sep 2015

ASV therapy used to treat central sleep apnoea in heart failure patients increases mortality

Adaptive servo-ventilation (ASV) therapy increases mortality and should not be used to treat central sleep apnoea in heart failure patients with reduced ejection fraction, the SERVE-HF trial shows.

1 Sep 2015

Scientists elucidate chemical process behind eosinophilic esophagitis

Scientists from the D'Or Institute of Research and Education, the Federal University of Rio de Janeiro and the Yale University School of Medicine have elucidated the chemical process behind a mysterious gastrointestinal disease that is becoming more frequent every day: the eosinophilic esophagitis (EoE), also known as the "asthma of the esophagus".

1 Sep 2015

Newly discovered prion causes Multiple System Atrophy

Multiple System Atrophy (MSA), a neurodegenerative disorder with similarities to Parkinson's disease, is caused by a newly discovered type of prion, akin to the misfolded proteins involved in incurable progressive brain diseases such Creutzfeldt-Jakob Disease (CJD), according to two new research papers led by scientists at UC San Francisco.

1 Sep 2015

Northwestern University receives $11.7 million NCI grant to use nanotechnology for cancer treatments

Northwestern University, a leader in cancer nanotechnology research, has received a five-year, $11.7 million grant from the National Cancer Institute to use nanotechnology to develop next-generation cancer treatments.

1 Sep 2015

Researchers discover that vitamin D may play significant role in preventing AMD among women

Vitamin D has been studied extensively in relation to bone health as well as cancer. Now, a team led by a researcher at the University at Buffalo has discovered that vitamin D may play a significant role in eye health, specifically in the possible prevention of age-related macular degeneration, or AMD, among women who are more genetically prone to developing the sight-damaging disease.

1 Sep 2015

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Bile duct cancer is rare and is usually detected too late. Often only extensive liver surgery can help or, in rare cases, liver transplantation. But which patients will benefit from surgery and which will not, because their risk of cancer recurrence is too high? With the oncogene MACC1 as a biomarker, physicians for the first time have a tool to decide which treatment option is best for patients with Klatskin carcinoma, one type of bile duct cancer.

1 Sep 2015

Penn Medicine hospitals named among HRC Foundation's 'Leader in LGBT Healthcare Equality' list

The Hospital of the University of Pennsylvania, Pennsylvania Hospital, Penn Presbyterian Medical Center, and Chester County Hospital were announced among the 2015 class of the Human Rights Campaign (HRC) Foundation's "Leader in LGBT Healthcare Equality" list, and the first to be announced in the organization's rolling admissions in 2015.

1 Sep 2015

New $6.25 million NIH grant to help investigators launch research center to slow and stop HIV

A new five-year, $6.25 million grant from the National Institutes of Health will help investigators from Northwestern University, the University of Chicago and others across the city of Chicago work together to slow and stop HIV.

1 Sep 2015

Repetitive transcranial magnetic stimulation can alleviate FOG, improve motor skills in PD patients

About 50% of patients with Parkinson's disease (PD) experience freezing of gait (FOG), an inability to move forward while walking. This can affect not only mobility but also balance. In a new study published in Restorative Neurology and Neuroscience, researchers report that repetitive transcranial magnetic stimulation (rTMS) can reduce FOG and improve other motor skills in PD patients.

1 Sep 2015

Performance Health's 2015 Scientific Advisory Committee meeting focuses on evidence-based practice

Performance Health held its 17th annual Scientific Advisory Committee meeting (known as TRAC) in Vancouver, Canada. Seventeen researchers and clinicians, representing five countries and expertise in physical therapy, chiropractic, exercise science, athletic training, and massage therapy, presented their research on Performance Health products, including TheraBand, Biofreeze and Cramer brands.

1 Sep 2015

New report highlights need for accurate diagnosis and management of bipolar I disorder

A new report launched today, ‘Paying the ultimate price’, highlights the urgent need for accurate diagnosis and management of bipolar I disorder in order to address a significant burden on society, patients and carers.

1 Sep 2015

Jersey Shore to break ground on HOPE Tower to provide new healing outpatient experience for the community

Jersey Shore University Medical Center, part of the Meridian Health family, is preparing to break ground this fall on the HOPE Tower Project - a $265 million dollar building development on the hospital's east campus that will provide a new healing outpatient experience for the community. HOPE Tower's expected date of completion is early 2018.

1 Sep 2015

Multiple HIV-1 variants at the beginning of infection impact viral load setpoints

HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to a paper published today in the journal Nature Medicine.

1 Sep 2015

New way to understand how transcranial magnetic stimulation can give relief for severe depression

A group of UK scientists have found a way of understanding how transcranial magnetic stimulation (TMS) can give relief to severely depressed patients. TMS is used as an alternative to Electro-Convulsive Therapy (ECT), but it is not known how it achieves its therapeutic effect. Understanding how it works may open the door to better, more targeted treatment for depression and other conditions.

31 Aug 2015

Study: Depressed patients three times more likely to experience frequent chest pain

Depressed patients have more frequent chest pain even in the absence of coronary artery disease, according to results from the Emory Cardiovascular Biobank presented at ESC Congress today by Dr Salim Hayek, a cardiologist at Emory University School of Medicine in Atlanta, Georgia, US.

31 Aug 2015

Prolonged television watching associated with twice the risk of fatal pulmonary embolism

Prolonged television watchers have a higher risk of fatal pulmonary embolism, a condition associated with long haul flights, reveals research presented at ESC Congress today by Mr Toru Shirakawa, public health research fellow in the Department of Social Medicine at Osaka University in Japan.

31 Aug 2015

Leadless cardiac pacemakers could overcome complications of conventional transvenous pacemakers

A leadless cardiac pacemaker showed "good safety and reliable function" during the initial six months of follow-up in the LEADLESS II study, investigators reported during a Hot Line presentation at the ESC congress 2015.

31 Aug 2015

LCZ696 reduces aortic systolic blood pressure, pulse pressure in hypertensive patients

The combination drug valsartan/sacubitril known as LCZ696 significantly reduced aortic systolic blood pressure and pulse pressure compared to the standard angiotensin receptor blocker (ARB) olmesartan in patients with hypertension, according to results of the PARAMETER study.

31 Aug 2015

Medicine News and Research

Benznidazole has significant antiparasitic activity, but does not reduce progression of Chagas cardiomyopathy

Abbott reports positive results of ABSORB Japan study comparing efficacy of fully dissolving heart stent to XIENCE

ASV therapy used to treat central sleep apnoea in heart failure patients increases mortality

Scientists elucidate chemical process behind eosinophilic esophagitis

Newly discovered prion causes Multiple System Atrophy

Northwestern University receives $11.7 million NCI grant to use nanotechnology for cancer treatments

Researchers discover that vitamin D may play significant role in preventing AMD among women

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Penn Medicine hospitals named among HRC Foundation's 'Leader in LGBT Healthcare Equality' list

New $6.25 million NIH grant to help investigators launch research center to slow and stop HIV

Repetitive transcranial magnetic stimulation can alleviate FOG, improve motor skills in PD patients

Performance Health's 2015 Scientific Advisory Committee meeting focuses on evidence-based practice

New report highlights need for accurate diagnosis and management of bipolar I disorder

Jersey Shore to break ground on HOPE Tower to provide new healing outpatient experience for the community

Multiple HIV-1 variants at the beginning of infection impact viral load setpoints

New way to understand how transcranial magnetic stimulation can give relief for severe depression

Study: Depressed patients three times more likely to experience frequent chest pain

Prolonged television watching associated with twice the risk of fatal pulmonary embolism

Leadless cardiac pacemakers could overcome complications of conventional transvenous pacemakers

LCZ696 reduces aortic systolic blood pressure, pulse pressure in hypertensive patients

Everything there is to know about biosimilars eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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