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Diabetes drug’s new weight loss formula fuels cost-benefit debate

The long list of side effects that follow ads for the newer expensive drugs to treat Type 2 diabetes sometimes include an unusual warning: They might cause weight loss. That side effect is one that many people — especially those with Type 2 diabetes, which is associated with obesity — may desperately want.

30 Jul 2021

Bus stop by bus stop, Denver-area officials microtarget vaccine hesitancy

John Letson had seen too many apocalyptic movies to feel comfortable getting a covid-19 vaccine initially.

30 Jul 2021

Amid covid booster debate, West Virginia to check immunity of vaccinated nursing home residents

West Virginia raced ahead of the country last winter to get people in nursing homes vaccinated against covid-19, but with cases and hospitalizations on the rise again, state officials want to know whether immunity levels are falling for residents who had their shots.

30 Jul 2021

BNT162b2 vaccine shows high efficacy at six months

The Pfizer/BioNTech vaccine appears to be highly effective in protecting against the SARS-CoV-2 infection, including its relatively resistant beta variant B.1.351.

30 Jul 2021

Prior SARS-CoV-2 infection enhances Johnson and Johnson Ad26.COV2.S vaccine immunogenicity

A new study reports that the Johnson and Johnson vaccine against COVID-19 shows enhanced efficacy when administered to individuals with pre-existing antibodies.

30 Jul 2021

Cash vouchers provide greater incentive for COVID-19 vaccines than lotteries

A new study focuses on cash vs lottery incentives to increase the acceptance of COVID-19 vaccines among unvaccinated adults in the USA.

30 Jul 2021

Next generation automation lab achieves huge productivity gains

Eli Lilly and Company and their industry partners, including sample management specialists – Ziath, are speeding the discovery of new medicines through the fully automated Lilly Life Sciences Studio lab in San Diego, USA.

From Ziath Ltd 30 Jul 2021

In-silico prediction of effective drug combinations for the treatment of SARS-CoV-2 infection

A new study published on the bioRxiv preprint server has developed the first computational model, i.e., a signaling network model, that can predict effective repurposed drug combinations to treat different phases of COVID-19 disease. This study has focused on identifying drugs for the treatment of early- and late-stage severe disease.

30 Jul 2021

Scientists suspect Lambda SARS-CoV-2 variant most dangerous

A new study published on the bioRxiv* preprint server used molecular phylogenetic analysis to study the evolutionary trait of the Lambda variant.

30 Jul 2021

Large nanodiscs simulate viral entry into host cells

In a paper recently uploaded to the journal Frontiers in Biotechnology by Padmanabha Das et al. (June 12th, 2020), a method of producing significantly larger homogenous nanodiscs up to 90 nm in diameter is described, and the advantages and applications of such nanodiscs are explored: better replicating the actual curvature and membrane symmetry of a real cell membrane, and allowing much larger or multiple membrane proteins to be loaded simultaneously.

30 Jul 2021

Study reveals cellular basis of antigen-specific response to Pfizer-BioNTech’s COVID-19 vaccine

Researchers in the United States have provided important insights into the antigen-specific cellular response and evolving humoral (antibody) response to messenger RNA- (mRNA) based vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

29 Jul 2021

Study compares the impacts of various race-free equations on kidney disease diagnoses

Equations that estimate individuals' kidney function currently include an adjustment for race. A study appearing in an upcoming issue of JASN compares various race-free equations and their expected impacts on kidney disease diagnoses.

29 Jul 2021

Study supports UK’s decision to extend second COVID-19 vaccination to 12 weeks

Findings from a study conducted in the UK support the country’s decision to extend the dosing interval of coronavirus disease 2019 (COVID-19) vaccination from 3 weeks to 12 weeks in order to prioritize the first dose for those at high risk of severe disease and death.

29 Jul 2021

Research finds associations between COVID-19 and persistent cognitive deficits

Much has been learned about SARS-CoV-2, the virus that causes the novel coronavirus, since the beginning of the COVID-19 pandemic. However, questions remain about the long-term impact of the virus on our bodies and brains.

29 Jul 2021

New insights into participation of underrepresented communities in Alzheimer’s clinical trials

A significant hurdle in developing therapeutics and care models for Alzheimer's disease that work for people of all ethnic and racial backgrounds is the recruitment and retention of traditionally underrepresented groups in clinical trials.

29 Jul 2021

Drug combination could make curative surgery possible for some liver cancer patients

A combination of the kinase-inhibitor drug cabozantinib and the immunotherapy drug nivolumab can make curative surgery possible in some liver cancer patients who would normally not be considered surgery candidates.

29 Jul 2021

New study shines light on how plant cells perceive and respond to mechanical forces

Minuscule tunnels through the cell membrane help cells to perceive and respond to mechanical forces, such as pressure or touch. A new study in the journal Science is among the first to directly investigate what one type of these mechanosensitive ion channels is doing in the tip-growing cells in moss and pollen tubes of flowering plants, and how.

29 Jul 2021

Climate change likely to exacerbate human-wildlife conflict

With wildfires spreading across the parched Western U.S., severe floods in Europe and in the coming decade a potential surge in coastal flooding, 2021 could be a pivotal year in how governments, societies and families view the threat of climate change.

29 Jul 2021

Vitamin D supplements are not effective for easing painful IBS symptoms, study reveals

Vitamin D supplements are not an effective treatment for easing painful symptoms of Irritable Bowel Syndrome (IBS), a new study from the University of Sheffield reveals.

29 Jul 2021

ICTER scientists improve the precision of cornea imaging using a non-invasive method

Until recently, researchers could mainly observe the eye cornea through a close microscope contact with living, or dead cells.

29 Jul 2021

Research News and Research

Diabetes drug’s new weight loss formula fuels cost-benefit debate

Bus stop by bus stop, Denver-area officials microtarget vaccine hesitancy

Amid covid booster debate, West Virginia to check immunity of vaccinated nursing home residents

BNT162b2 vaccine shows high efficacy at six months

Prior SARS-CoV-2 infection enhances Johnson and Johnson Ad26.COV2.S vaccine immunogenicity

Cash vouchers provide greater incentive for COVID-19 vaccines than lotteries

Next generation automation lab achieves huge productivity gains

In-silico prediction of effective drug combinations for the treatment of SARS-CoV-2 infection

Scientists suspect Lambda SARS-CoV-2 variant most dangerous

Large nanodiscs simulate viral entry into host cells

Study reveals cellular basis of antigen-specific response to Pfizer-BioNTech’s COVID-19 vaccine

Study compares the impacts of various race-free equations on kidney disease diagnoses

Study supports UK’s decision to extend second COVID-19 vaccination to 12 weeks

Research finds associations between COVID-19 and persistent cognitive deficits

New insights into participation of underrepresented communities in Alzheimer’s clinical trials

Drug combination could make curative surgery possible for some liver cancer patients

New study shines light on how plant cells perceive and respond to mechanical forces

Climate change likely to exacerbate human-wildlife conflict

Vitamin D supplements are not effective for easing painful IBS symptoms, study reveals

ICTER scientists improve the precision of cornea imaging using a non-invasive method

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